Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gabriel Schweighauser"'
Autor:
Anna Khimchenko, Christos Bikis, Alexandra Pacureanu, Simone E. Hieber, Peter Thalmann, Hans Deyhle, Gabriel Schweighauser, Jürgen Hench, Stephan Frank, Magdalena Müller‐Gerbl, Georg Schulz, Peter Cloetens, Bert Müller
Publikováno v:
Advanced Science, Vol 5, Iss 6, Pp n/a-n/a (2018)
Abstract There have been great efforts on the nanoscale 3D probing of brain tissues to image subcellular morphologies. However, limitations in terms of tissue coverage, anisotropic resolution, stain dependence, and complex sample preparation all hind
Externí odkaz:
https://doaj.org/article/3a7fc29e6df04d5780837b23feb6542d
Autor:
Paula P Navarro, Amanda J Lewis, Tim Moors, Jürgen Hench, Wilma D.J. van de Berg, Jing Wang, Vincenzo Bonifati, Andreas Staempfli, Markus Britschgi, Annemieke J.M. Rozemuller, Frederik Großerüschkamp, Henning Stahlberg, Stephan Frank, Evelien Huisman, Klaus Gerwert, Daniel Niedieker, Wilfred F. J. van IJcken, Yvonne de Gier, Rosmarie Sütterlin, Gabriel Schweighauser, Angela Ingrassia, Kenneth N. Goldie, Joerg Hoernschemeyer, Anne De Paepe, Sarah H Shahmoradian, Matthias E. Lauer, Johannes Erny, Alexandra Graff-Meyer, Christel Genoud, Marialuisa Quadri, Bernd Bohrmann, Daniel Castaño-Díez, Samir F. El-Mashtoly
Publikováno v:
Shahmoradian, S H, Lewis, A J, Genoud, C, Hench, J R, Moors, T E, Navarro, P P, Castaño-Díez, D, Schweighauser, G, Graff-Meyer, A, Goldie, K N, Sütterlin, R, Huisman, E, Ingrassia, A, Gier, Y D, Rozemuller, A J M, Wang, J, Paepe, A D, Erny, J, Staempfli, A, Hoernschemeyer, J, Großerüschkamp, F, Niedieker, D, el-Mashtoly, S F, Quadri, M, van IJcken, W F J, Bonifati, V, Gerwert, K, Bohrmann, B, Frank, S, Britschgi, M, Stahlberg, H, van de Berg, W D J & Lauer, M E 2019, ' Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes ', Nature Neuroscience, vol. 22, no. 7, pp. 1099-1109 . https://doi.org/10.1038/s41593-019-0423-2
Nature Neuroscience, 22(7), 1099-+. Nature Publishing Group
Nature Neuroscience, 22(7), 1099-1109. Nature Publishing Group
Nature Neuroscience, 22(7), 1099-+. Nature Publishing Group
Nature Neuroscience, 22(7), 1099-1109. Nature Publishing Group
Parkinson's disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological hallmarks are Lewy bodies and Lewy neurites: neuronal inclusions immunopositive for the protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b1dc002c6518905c4185595a0f3b06
https://research.vumc.nl/en/publications/06f8f039-13aa-44ee-a512-b049e4ba1194
https://research.vumc.nl/en/publications/06f8f039-13aa-44ee-a512-b049e4ba1194
Autor:
Paula P Navarro, Alexandra Graff-Meyer, Jürgen Hench, Matthias E. Lauer, Bernd Bohrmann, Yvonne de Gier, Gabriel Schweighauser, Annemieke J.M. Rozemuller, Henning Stahlberg, Stephan Frank, Christel Genoud, Daniel Castaño-Díez, Sarah H Shahmoradian, Markus Britschgi, Amanda J Lewis, Wilma D.J. van de Berg
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, 8(1):18046. Nature Publishing Group
Navarro, P P, Genoud, C, Castaño-Díez, D, Graff-Meyer, A, Lewis, A J, de Gier, Y, Lauer, M E, Britschgi, M, Bohrmann, B, Frank, S, Hench, J, Schweighauser, G, Rozemuller, A J M, van de Berg, W D J, Stahlberg, H & Shahmoradian, S H 2018, ' Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles ', Scientific Reports, vol. 8, no. 1, 18046 . https://doi.org/10.1038/s41598-018-36223-4
Scientific Reports
Scientific Reports, 8(1):18046. Nature Publishing Group
Navarro, P P, Genoud, C, Castaño-Díez, D, Graff-Meyer, A, Lewis, A J, de Gier, Y, Lauer, M E, Britschgi, M, Bohrmann, B, Frank, S, Hench, J, Schweighauser, G, Rozemuller, A J M, van de Berg, W D J, Stahlberg, H & Shahmoradian, S H 2018, ' Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles ', Scientific Reports, vol. 8, no. 1, 18046 . https://doi.org/10.1038/s41598-018-36223-4
Scientific Reports
Corpora amylacea are cell-derived structures that appear physiologically in the aged human brain. While their histological identification is straightforward, their ultrastructural composition and microenvironment at the nanoscale have remained unclea
Autor:
Natalia Chicherova, Luigi Mariani, Hans Deyhle, Bert Müller, Philipp Janz, Carola A. Haas, Anna Khimchenko, Alexander Rack, Christos Bikis, Simone E. Hieber, Peter Thalmann, Georg Schulz, Jürgen Hench, Gabriel Schweighauser
Publikováno v:
DEVELOPMENTS IN X-RAY TOMOGRAPHY X
Phase-contrast micro-tomography using synchrotron radiation has yielded superior soft tissue visualization down to the sub-cellular level. The isotropic spatial resolution down to about one micron is comparable to the one of histology. The methods, h
Autor:
Peter Cloetens, Magdalena Müller-Gerbl, Christos Bikis, Jürgen Hench, Alexandra Pacureanu, Georg Schulz, Simone E. Hieber, Anna Khimchenko, Peter Thalmann, Hans Deyhle, Gabriel Schweighauser, Bert Müller, Stephan Frank
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 5(6)
There have been great efforts on the nanoscale 3D probing of brain tissues to image subcellular morphologies. However, limitations in terms of tissue coverage, anisotropic resolution, stain dependence, and complex sample preparation all hinder achiev
Autor:
Georg Schulz, Bekim Osmani, Gabriel Schweighauser, Magdalena Müller-Gerbl, Jürgen Hench, Peter Cloetens, Bert Müller, Alexandra-Teodora Joita-Pacureanu, Simone E. Hieber, Peter Thalmann, Hans Deyhle, Anna Khimchenko, Christos Bikis, Natalia Chicherova
Publikováno v:
Developments in X-Ray Tomography XI.
Brain tissues have been an attractive subject for investigations in neuropathology, neuroscience, and neurobiol- ogy. Nevertheless, existing imaging methodologies have intrinsic limitations in three-dimensional (3D) label-free visualisation of extend
Autor:
Sarah H. Shahmoradian, Amanda J. Lewis, Christel Genoud, Jürgen Hench, Tim Moors, Paula P. Navarro, Daniel Castaño-Díez, Gabriel Schweighauser, Alexandra Graff-Meyer, Kenneth N. Goldie, Rosmarie Sütterlin, Evelien Huisman, Angela Ingrassia, Yvonne de Gier, Annemieke J.M. Rozemuller, Jing Wang, Anne De Paepe, Johannes Erny, Andreas Staempfli, Joerg Hoernschemeyer, Frederik Großerüschkamp, Daniel Niedieker, Samir F. El-Mashtoly, Marialuisa Quadri, Wilfred F.J. van IJcken, Vincenzo Bonifati, Klaus Gerwert, Bernd Bohrmann, Stephan Frank, Markus Britschgi, Henning Stahlberg, Wilma D. J. van de Berg, Matthias E. Lauer
Publikováno v:
Biorxiv. Cold Spring Harbor Laboratory Press
Biorxiv
Sharamoradian, S, Britschgi, M, Stahlberg, H, van de Berg, WDJ & Lauer, M 2017, ' Lewy pathology in Parkinson's disease consists of a crowded organellar membranous medley ', Biorxiv .
Biorxiv
Sharamoradian, S, Britschgi, M, Stahlberg, H, van de Berg, WDJ & Lauer, M 2017, ' Lewy pathology in Parkinson's disease consists of a crowded organellar membranous medley ', Biorxiv .
SummaryParkinson’s disease, the most common age-related movement disorder, is a progressive neurodegenerative disease with unclear etiology. Key neuropathological hallmarks are Lewy bodies and Lewy neurites, which are neuronal inclusions that are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a478964199a15d6cd71c877c3585f2
https://doi.org/10.1101/137976
https://doi.org/10.1101/137976
Autor:
Anna Khimchenko, Georg Schulz, Natalia Chicherova, Hans Deyhle, Jürgen Hench, Bert Müller, Simone E. Hieber, Christos Bikis, Gabriel Schweighauser
Publikováno v:
SPIE Proceedings.
Our body is hierarchically organized down to individual cells. Cutting-edge clinical imaging facilities reach a spatial resolution of a fraction of a millimeter, living cells invisible. A decade ago, post-mortem X-ray imaging by means of synchrotron
Autor:
Simone E. Hieber, Peter Thalmann, Georg Schulz, Gabriel Schweighauser, Christos Bikis, Jürgen Hench, Marie-Christine Zdora, Alexander Hipp, Hans Deyhle, Bert Müller, Irene Zanette, Anna Khimchenko
Publikováno v:
Developments in X-Ray Tomography X
X-ray imaging in absorption contrast mode is well established for hard tissue visualization. However, performance for lower density materials is limited due to a reduced contrast. Our aim is three-dimensional (3D) characterization of micro-morphology
Autor:
Jürgen Hench, Alexander Rack, Irene Zanette, Georg Schulz, Gabriel Schweighauser, Christos Bikis, Simone E. Hieber, Peter Thalmann, Hans Deyhle, Marie-Christine Zdora, Bert Müller, Anna Khimchenko, Natalia Chicherova
Publikováno v:
Developments in X-Ray Tomography X
Cell visualization and counting plays a crucial role in biological and medical research including the study of neurodegenerative diseases. The neuronal cell loss is typically determined to measure the extent of the disease. Its characterization is ch