Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Gabriel R. Fries"'
Autor:
Thiago Wendt Viola, Christina Danzer, Victor Mardini, Claudia Szobot, João Henrique Chrusciel, Laura Stertz, Joy M. Schmitz, Consuelo Walss-Bass, Gabriel R. Fries, Rodrigo Grassi-Oliveira
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The investigation of the effects of prenatal cocaine exposure (PCE) on offspring has been inconsistent, with few studies investigating biological outcomes in humans. We profiled genome-wide DNA methylation (DNAm) of umbilical cord blood (UCB
Externí odkaz:
https://doaj.org/article/c7d1593095db41d287d401ecfeae2dc5
Autor:
Salahudeen Mirza, Camila N. C. Lima, Alexandra Del Favero-Campbell, Alexandre Rubinstein, Natasha Topolski, Brenda Cabrera-Mendoza, Emese H. C. Kovács, Hilary P. Blumberg, Jenny Gringer Richards, Aislinn J. Williams, John A. Wemmie, Vincent A. Magnotta, Jess G. Fiedorowicz, Marie E. Gaine, Consuelo Walss-Bass, Joao Quevedo, Jair C. Soares, Gabriel R. Fries
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Suicide attempt (SA) risk is elevated in individuals with bipolar disorder (BD), and DNA methylation patterns may serve as possible biomarkers of SA. We conducted epigenome-wide association studies (EWAS) of blood DNA methylation associated
Externí odkaz:
https://doaj.org/article/2ae4abdb7cb24c3186a4d6c90040d50b
Autor:
Emily F. Mendez, Sandra L. Grimm, Laura Stertz, Damian Gorski, Sai V. Movva, Katherine Najera, Karla Moriel, Thomas D. Meyer, Gabriel R. Fries, Cristian Coarfa, Consuelo Walss-Bass
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionHuman-derived induced pluripotent stem cell (iPSC) models of brain promise to advance our understanding of neurotoxic consequences of drug use. However, how well these models recapitulate the actual genomic landscape and cell function, as
Externí odkaz:
https://doaj.org/article/e69ef664aef746999f9747cf0a007401
Autor:
Salahudeen Mirza, Gabriel R. Fries
Publikováno v:
Brazilian Journal of Psychiatry (2023)
Externí odkaz:
https://doaj.org/article/23e088ce26614c1eb33f047c59614552
Autor:
Sandra L. Grimm, Emily F. Mendez, Laura Stertz, Thomas D. Meyer, Gabriel R. Fries, Tanmay Gandhi, Rupa Kanchi, Sudhakar Selvaraj, Antonio L. Teixeira, Thomas R. Kosten, Preethi Gunaratne, Cristian Coarfa, Consuelo Walss-Bass
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2023)
IntroductionTo understand mechanisms and identify potential targets for intervention in the current crisis of opioid use disorder (OUD), postmortem brains represent an under-utilized resource. To refine previously reported gene signatures of neurobio
Externí odkaz:
https://doaj.org/article/30ce589188ff4ac08d007ac66ff28274
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Genome-wide screenings of “essential genes”, i.e., genes required for an organism or cell survival, have been traditionally conducted in vitro in cancer cell lines, limiting the translation of results to other tissues and non-cancerous c
Externí odkaz:
https://doaj.org/article/d9cf2efa29c942eaae1b7096d29c776d
Autor:
Ning O. Zhao, Natasha Topolski, Massimo Tusconi, Erika M. Salarda, Christopher W. Busby, Camila N.N.C. Lima, Anilkumar Pillai, Joao Quevedo, Tatiana Barichello, Gabriel R. Fries
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 21, Iss , Pp 100441- (2022)
Bipolar disorder (BD) is a severe psychiatric disorder affecting approximately 1–3% of the population and characterized by a chronic and recurrent course of debilitating symptoms. An increasing focus has been directed to discover and explain the fu
Externí odkaz:
https://doaj.org/article/35eb54cd9dcd46878c3751284638c77e
Autor:
Lucca Pizzato Tondo, Thiago Wendt Viola, Gabriel R. Fries, Bruno Kluwe-Schiavon, Leonardo Mello Rothmann, Renata Cupertino, Pedro Ferreira, Alexandre Rosa Franco, Scott D. Lane, Laura Stertz, Zhongming Zhao, Ruifeng Hu, Thomas Meyer, Joy M. Schmitz, Consuelo Walss-Bass, Rodrigo Grassi-Oliveira
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract White matter (WM) abnormalities in patients with cocaine use disorder (CUD) have been studied; however, the reported effects on the human brain are heterogenous and most results have been obtained from male participants. In addition, biologi
Externí odkaz:
https://doaj.org/article/5e8c57109d434cb0a66f0fda1c82cff9
Autor:
Angelica Cerveira de Baumont, Mauricio Scopel Hoffmann, Andressa Bortoluzzi, Gabriel R. Fries, Patrícia Lavandoski, Lucas K. Grun, Luciano S. P. Guimarães, Fátima T. C. R. Guma, Giovanni Abrahão Salum, Florencia M. Barbé-Tuana, Gisele G. Manfro
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Evidence on the relationship between genetics and mental health are flourishing. However, few studies are evaluating early biomarkers that might link genes, environment, and psychopathology. We aimed to study telomere length (TL) and epigene
Externí odkaz:
https://doaj.org/article/9b464780231e441eb7f7ca69eb08079a
Autor:
Giselli Scaini, Samira S. Valvassori, Alexandre P. Diaz, Camila N. Lima, Deborah Benevenuto, Gabriel R. Fries, Joao Quevedo
Publikováno v:
Brazilian Journal of Psychiatry, Vol 42, Iss 5, Pp 536-551 (2020)
Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed states, often associated with functional impairment. Although effective pharmacological and
Externí odkaz:
https://doaj.org/article/bab686c2a2c947dd8b49957b8dd4267b