Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gabriel Núñez‐Vivanco"'
Autor:
Alejandro Valdés-Jiménez, Daniel Jiménez-González, Aytug K. Kiper, Susanne Rinné, Niels Decher, Wendy González, Miguel Reyes-Parada, Gabriel Núñez-Vivanco
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The identification of similar three-dimensional (3D) amino acid patterns among different proteins might be helpful to explain the polypharmacological profile of many currently used drugs. Also, it would be a reasonable first step for the design of no
Externí odkaz:
https://doaj.org/article/197170dac86541658f2b64ec95dd9c6f
Autor:
Juan Pablo González-Gutiérrez, Hernán Armando Pessoa-Mahana, Patricio Ernesto Iturriaga-Vásquez, Miguel Iván Reyes-Parada, Nicolas Esteban Guerra-Díaz, Martin Hodar-Salazar, Franco Viscarra, Pablo Paillali, Gabriel Núñez-Vivanco, Marcos Antonio Lorca-Carvajal, Jaime Mella-Raipán, María Carolina Zúñiga
Publikováno v:
Molecules, Vol 24, Iss 20, p 3808 (2019)
Nicotinic acetylcholine receptors (nAChRs), serotonin transporters (SERT) and dopamine transporters (DAT) represent targets for the development of novel nicotinic derivatives acting as multiligands associated with different health conditions, such as
Externí odkaz:
https://doaj.org/article/54b84d602fb54176b3b2e06d275c291c
Autor:
Gabriel Núñez-Vivanco, Angélica Fierro, Pablo Moya, Patricio Iturriaga-Vásquez, Miguel Reyes-Parada
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200637 (2018)
The study of binding site similarities can be relevant to understand the interaction of different drugs at several molecular targets. The increasing availability of protein crystal structures and the development of novel algorithms designed to evalua
Externí odkaz:
https://doaj.org/article/7b5a8916c3d64e4f868707fda299f4de
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3174 (2019)
Discovering conserved three-dimensional (3D) patterns among protein structures may provide valuable insights into protein classification, functional annotations or the rational design of multi-target drugs. Thus, several computational tools have been
Externí odkaz:
https://doaj.org/article/e31ba9fb812e40ad8ddb7d947fab0ee5
Autor:
Florencia Spirito, Paula Meli, M. Fernanda Reyes, Gabriel Núñez‐Vivanco, Zoe Beloff, Josefina L. De Paepe
Publikováno v:
Austral Ecology.
Autor:
Julio Caballero, Gabriel Núñez-Vivanco, José Luis Velázquez-Libera, Alejandro Valdés-Jiménez, Fabio Durán-Verdugo
Publikováno v:
Bioinformatics. 36:2912-2914
Motivation Root mean square deviation (RMSD) is one of the most useful and straightforward features for structural comparison between different conformations of the same molecule. Commonly, protein-ligand docking programs have included some utilities
Autor:
Gabriel Núñez-Vivanco, Gonzalo E. Torres, Gabriela Hidalgo, Jose A. Pino, Miguel Reyes Parada, Habibeh Khoshbouei
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
The dopamine transporter (DAT) plays a crucial role in the regulation of brain dopamine (DA) homeostasis through the re-uptake of DA back into the presynaptic terminal. In addition to re-uptake, DAT is also able to release DA through a process referr
Publikováno v:
Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th edition.
Most of drugs interact with more than one molecular target. This fact typically would be seen like as an undesired feature of a pharmacological treatment, however, current trends in drug discovery has put hope and several efforts in the improved effi
Autor:
Gabriel Núñez-Vivanco, Alejandro Valdés-Jiménez, David Ramírez, Ingo Dreyer, Carlos Peña-Varas, Hussam Hassan Nour-Eldin, Lily Arrué, Paola Borrego-Muñoz, Melissa Alegría-Arcos
Publikováno v:
Valdes-Jimenez, A, Pena-Varas, C, Borrego-Munoz, P, Arrue, L, Alegria-Arcos, M, Nour-Eldin, H, Dreyer, I, Nunez-Vivanco, G & Ramirez, D 2021, ' PSC-db : A Structured and Searchable 3D-Database for Plant Secondary Compounds ', Molecules, vol. 26, no. 4, 1124 . https://doi.org/10.3390/molecules26041124
Molecules
Molecules, Vol 26, Iss 1124, p 1124 (2021)
Volume 26
Issue 4
Molecules
Molecules, Vol 26, Iss 1124, p 1124 (2021)
Volume 26
Issue 4
Plants synthesize a large number of natural products, many of which are bioactive and have practical values as well as commercial potential. To explore this vast structural diversity, we present PSC-db, a unique plant metabolite database aimed to cat
Autor:
Bárbara Arévalo, Susanne Rinné, Gabriel Núñez-Vivanco, Miguel Reyes-Parada, Wendy González, Vladimir Yarov-Yarovoy, Mauricio Bedoya, Aytug K. Kiper, José Márquez-Montesinos, Niels Decher, David Ramírez
Publikováno v:
Biophysical Journal. 120:248a