Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Gabriel N, Aughey"'
Autor:
Gabriel N. Aughey
Publikováno v:
Biology Open, Vol 12, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/06c8fc9bf7d748669a731c8c06b0c5f9
Autor:
Colin D McClure, Amira Hassan, Gabriel N Aughey, Khushbakht Butt, Alicia Estacio-Gómez, Aneisha Duggal, Chee Ying Sia, Annika F Barber, Tony D Southall
Publikováno v:
eLife, Vol 11 (2022)
The ability to control transgene expression, both spatially and temporally, is essential for studying model organisms. In Drosophila, spatial control is primarily provided by the GAL4/UAS system, whilst temporal control relies on a temperature-sensit
Externí odkaz:
https://doaj.org/article/dcdad00f61fb41b3849a67a46ff4af8a
Autor:
Amira Hassan, Pablo Araguas Rodriguez, Stefan K Heidmann, Emma L Walmsley, Gabriel N Aughey, Tony D Southall
Publikováno v:
eLife, Vol 9 (2020)
Condensin complexes are essential for mitotic chromosome assembly and segregation during cell divisions, however, little is known about their functions in post-mitotic cells. Here we report a role for the condensin I subunit Cap-G in Drosophila neuro
Externí odkaz:
https://doaj.org/article/a906388da72d428c8515582db36a41f5
During neuronal development, extensive changes to chromatin states occur to regulate lineage-specific gene expression. The molecular factors underlying the repression of non-neuronal genes in differentiated neurons are poorly characterised. The Mi2/N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8301d083b4168b16080be50c998a7f6c
http://hdl.handle.net/10044/1/102780
http://hdl.handle.net/10044/1/102780
Publikováno v:
eLife, Vol 7 (2018)
During development eukaryotic gene expression is coordinated by dynamic changes in chromatin structure. Measurements of accessible chromatin are used extensively to identify genomic regulatory elements. Whilst chromatin landscapes of pluripotent stem
Externí odkaz:
https://doaj.org/article/bd352654e2b54b73a315422bfae47a47
Autor:
Krista Grimes, Esteban J. Beckwith, William H. Pearson, Jake Jacobson, Surabhi Chaudhari, Gabriel N. Aughey, Gerald Larrouy-Maumus, Tony D. Southall, Marc S. Dionne
Immune activation drives metabolic change in most animals. Immune-induced metabolic change is most conspicuous as a driver of pathology in serious or prolonged infection, but it is normally expected to be important to support immune function and reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7819fac8d88dd1782406071539863cfc
https://doi.org/10.1101/2022.11.25.517956
https://doi.org/10.1101/2022.11.25.517956
Autor:
Gabriel N. Aughey, Stuart J. Grice, Qing-Ji Shen, Yichi Xu, Chia-Chun Chang, Ghows Azzam, Pei-Yu Wang, Luke Freeman-Mills, Li-Mei Pai, Li-Ying Sung, Jun Yan, Ji-Long Liu
Publikováno v:
Biology Open, Vol 3, Iss 11, Pp 1045-1056 (2014)
The essential metabolic enzyme CTP synthase (CTPsyn) can be compartmentalised to form an evolutionarily-conserved intracellular structure termed the cytoophidium. Recently, it has been demonstrated that the enzymatic activity of CTPsyn is attenuated
Externí odkaz:
https://doaj.org/article/8ac2f8470e1a4573a8bbc4dc84920784
Autor:
Tony D. Southall, Jessica Perochon, André B. Medina, Gabriel N. Aughey, Yachuan Yu, Julia B. Cordero
Publikováno v:
Nature cell biology
Coordination of stem cell function by local and niche-derived signals is essential to preserve adult tissue homeostasis and organismal health. The vasculature is a prominent component of multiple stem cell niches. However, its role in adult intestina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0701fd00f8cc7716dac23b68f18f309d
http://europepmc.org/articles/PMC7610788
http://europepmc.org/articles/PMC7610788
Publikováno v:
G3: Genes|Genomes|Genetics
Targeted DamID (TaDa) is an increasingly popular method of generating cell-type-specific DNA-binding profiles in vivo. Although sensitive and versatile, TaDa requires the generation of new transgenic fly lines for every protein that is profiled, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4bdb95c514d797768b7f195474097e1
https://doi.org/10.1093/g3journal/jkaa005
https://doi.org/10.1093/g3journal/jkaa005
Autor:
Amira Hassan, Colin D McClure, Gabriel N Aughey, Khushbakht Butt, Alicia Estacio-Gómez, Aneisha Duggal, Chee Ying Sia, Annika F Barber, Tony D Southall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fbf4f78bead0da5ae1bba791d607902
https://doi.org/10.7554/elife.67598.sa2
https://doi.org/10.7554/elife.67598.sa2