Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Gabriel Mazzucchelli"'
Autor:
Nicolas Papadopoulos, Audrey Nédélec, Allison Derenne, Teodor Asvadur Şulea, Christian Pecquet, Ilyas Chachoua, Gaëlle Vertenoeil, Thomas Tilmant, Andrei-Jose Petrescu, Gabriel Mazzucchelli, Bogdan I. Iorga, Didier Vertommen, Stefan N. Constantinescu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
In myeloproliferative neoplasms, frameshift mutants of calreticulin turn into rogue cytokines by inducing constitutive activation of the Thrombopoietin Receptor (TpoR). Here, the authors define how mutant calreticulin acquires specificity for TpoR bi
Externí odkaz:
https://doaj.org/article/2608cc9507e54cfda715fbc3e86b7d63
Autor:
Alizee Lebeau, Diane Bruyere, Patrick Roncarati, Paul Peixoto, Eric Hervouet, Gael Cobraiville, Bernard Taminiau, Murielle Masson, Carmen Gallego, Gabriel Mazzucchelli, Nicolas Smargiasso, Maximilien Fleron, Dominique Baiwir, Elodie Hendrick, Charlotte Pilard, Thomas Lerho, Celia Reynders, Marie Ancion, Roland Greimers, Jean-Claude Twizere, Georges Daube, Geraldine Schlecht-Louf, Françoise Bachelerie, Jean-Damien Combes, Pierrette Melin, Marianne Fillet, Philippe Delvenne, Pascale Hubert, Michael Herfs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Here, the authors show that HPV infection leads to downregulation of host mucosal innate peptides, which are in turn used by predominant Lactobacillus species as amino acid source, promoting ultimately an imbalance in the vaginal flora.
Externí odkaz:
https://doaj.org/article/521ef97d899041439a6f7558c5e56b61
Autor:
Francesca Rapino, Zhaoli Zhou, Ana Maria Roncero Sanchez, Marc Joiret, Christian Seca, Najla El Hachem, Gianluca Valenti, Sara Latini, Kateryna Shostak, Liesbet Geris, Ping Li, Gang Huang, Gabriel Mazzucchelli, Dominique Baiwir, Christophe J. Desmet, Alain Chariot, Michel Georges, Pierre Close
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Wobble uridine (U34) tRNA modifications are important for the decoding of AA-ending codons. Here the authors show that while the U34-codon content of mRNAs are predictive of changes in ribosome translation elongation, the resulting outcome in protein
Externí odkaz:
https://doaj.org/article/c065fd32e605402394e0d38dfe8266a8
Autor:
Fernanda Gobbi Amorim, Damien Redureau, Thomas Crasset, Lou Freuville, Dominique Baiwir, Gabriel Mazzucchelli, Stefanie K. Menzies, Nicholas R. Casewell, Loïc Quinton
Publikováno v:
Toxins, Vol 15, Iss 6, p 357 (2023)
To improve the characterization of snake venom protein profiles, we report the application of a new generation of proteomic methodology to deeply characterize complex protein mixtures. The new approach, combining a synergic multi-enzymatic and a time
Externí odkaz:
https://doaj.org/article/97a8fd87f81a453d9748ec154227c54f
Autor:
Federica Ciregia, Dominique Baiwir, Gaël Cobraiville, Thibaut Dewael, Gabriel Mazzucchelli, Valérie Badot, Silvana Di Romana, Paschalis Sidiras, Tatiana Sokolova, Patrick Durez, Michel G. Malaise, Dominique de Seny
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Serum protein glycosylation is an area of investigation in inflammatory arthritic disorders such as rheumatoid arthritis (RA). Indeed, some studies highlighted abnormalities of protein glycosylation in RA. Considering the numerous
Externí odkaz:
https://doaj.org/article/dbecf825f97b4b248c7d064730529f27
Autor:
Géraldine Luis, Adrien Godfroid, Shin Nishiumi, Jonathan Cimino, Silvia Blacher, Erik Maquoi, Coline Wery, Alice Collignon, Rémi Longuespée, Laetitia Montero-Ruiz, Isabelle Dassoul, Naima Maloujahmoum, Charles Pottier, Gabriel Mazzucchelli, Edwin Depauw, Akeila Bellahcène, Masaru Yoshida, Agnès Noel, Nor Eddine Sounni
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102006- (2021)
Problem: Tumor recurrence is a major clinical issue that represents the principal cause of cancer-related deaths, with few targetable common pathways. Mechanisms by which residual tumors persist and progress under a continuous shift between hypoxia-r
Externí odkaz:
https://doaj.org/article/3eb5ddbabbf94bec843e6e8d4acb98c3
Autor:
Bastien Burat, Audrey Reynaerts, Dominique Baiwir, Maximilien Fléron, Sophie Gohy, Gauthier Eppe, Teresinha Leal, Gabriel Mazzucchelli
Publikováno v:
Cells, Vol 11, Iss 15, p 2358 (2022)
In clinical routine, the diagnosis of cystic fibrosis (CF) is still challenging regardless of international consensus on diagnosis guidelines and tests. For decades, the classical Gibson and Cooke test measuring sweat chloride concentration has been
Externí odkaz:
https://doaj.org/article/bc1386f8871e4bd298f1592085fb667f
Autor:
Cédric Leduc, Laura Dupont, Loïc Joannes, Christine Monseur, Dominique Baiwir, Gabriel Mazzucchelli, Christophe Deroanne, Alain Colige, Mourad Bekhouche
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
A disintegrin and metalloproteinase with thrombospondin type I motif (ADAMTS)2 and ADAMTS14 were originally known for their ability to cleave the aminopropeptides of fibrillar collagens. Previous work using N-terminomic approach (N-TAILS) in vitro le
Externí odkaz:
https://doaj.org/article/0e2d74ab9583463cbabd722ae533ef04
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 752 (2022)
Ferroverdins are ferrous iron (Fe2+)-nitrosophenolato complexes produced by a few Streptomyces species as a response to iron overload. Previously, three ferroverdins were identified: ferroverdin A, in which three molecules of p-vinylphenyl-3-nitroso-
Externí odkaz:
https://doaj.org/article/4b0e5b6b37524842a14993e40a9e736c
Autor:
Dieu-Hien Truong, Hoang Chinh Nguyen, Julien Bauwens, Gabriel Mazzucchelli, Georges Lognay, Frédéric Francis
Publikováno v:
Journal of Plant Interactions, Vol 13, Iss 1, Pp 30-36 (2018)
The interactions between Arabidopsis thaliana and Plutella xylostella have been considered as a model system to unravel the responses of plants to herbivorous insects. Here, we use a 2-DE proteome approach to detect protein expression changes in the
Externí odkaz:
https://doaj.org/article/0b0854031f5845959fbddee0dec8c243