Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Gabriel M. Pagnotti"'
Autor:
Cody McGrath, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Buer Sen, Zhihui Xie, Gunes Uzer, Guniz B. Uzer, Xiaopeng Zong, Martin A. Styner, Janet Rubin, Maya Styner
Publikováno v:
Obesity Facts, Pp 1-13 (2024)
Introduction: Longitudinal effect of diet-induced obesity on bone is uncertain. Prior work showed both no effect and a decrement in bone density or quality when obesity begins prior to skeletal maturity. We aimed to quantify long-term effects of obes
Externí odkaz:
https://doaj.org/article/e65a38454ea74e49b05eba95071a34e4
Autor:
Lei Shi, Sukanya Suresh, Truc Kuo, Anand Singh, Jade Martinez, Trupti Trivedi, Gabriel M. Pagnotti, Leah D. Guerra, Xu Cao, Theresa A. Guise
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100536- (2024)
Externí odkaz:
https://doaj.org/article/afcbd25c92a54294b26c158068776105
Autor:
Trupti Trivedi, Gabriel M. Pagnotti, Sukanya Suresh, Yun She, Sreemala Murthy, Jade Martinez, Carmella-Evans Molina, Khalid S. Mohammad, Theresa A. Guise
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100587- (2024)
Externí odkaz:
https://doaj.org/article/d0b7f28991ed4eca8e5052c0099eb7aa
Autor:
Jing Fu, Shirong Li, Huihui Ma, Jun Yang, Gabriel M. Pagnotti, Lewis M. Brown, Stephen J. Weiss, Markus Y. Mapara, Suzanne Lentzsch
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Multiple myeloma bone disease is characterized by the development of osteolytic bone lesions. Recent work identified matrix metalloproteinase 13 as a myeloma-derived fusogen that induces osteoclast activation independent of its proteolytic a
Externí odkaz:
https://doaj.org/article/598e93ce7fc24e4a9c7f88a2a8fa8488
Autor:
Gabriel M. Pagnotti, Amna Haider, Ariel Yang, Kathryn E. Cottell, Catherine M. Tuppo, Kai-Yu Tong, Aurora D. Pryor, Clinton T. Rubin, M. Ete Chan
Publikováno v:
Obesity Facts, Vol 13, Iss 5, Pp 499-513 (2020)
Introduction: Globally, 300 million adults have clinical obesity. Heightened adiposity and inadequate musculature secondary to obesity alter bipedal stance and gait, diminish musculoskeletal tissue quality, and compromise neuromuscular feedback; thes
Externí odkaz:
https://doaj.org/article/521df5fba8cd464080ebd94c219113b3
Publikováno v:
Cells, Vol 11, Iss 8, p 1309 (2022)
Metastatic bone disease is a common and devastating complication to cancer, confounding treatments and recovery efforts and presenting a significant barrier to de-escalating the adverse outcomes associated with disease progression. Despite significan
Externí odkaz:
https://doaj.org/article/42b25d0c60f3451bb4192e0a9a61bfcb
Publikováno v:
Biomolecules, Vol 11, Iss 11, p 1643 (2021)
Complications associated with advanced cancer are a major clinical challenge and, if associated with bone metastases, worsen the prognosis and compromise the survival of the patients. Breast and prostate cancer cells exhibit a high propensity to meta
Externí odkaz:
https://doaj.org/article/bcea8097de5c448abc431ca453ee68b0
Autor:
Gabriel M. Pagnotti, Trupti Trivedi, Laura E. Wright, Sutha K. John, Sreemala Murthy, Ryan R. Pattyn, Monte S. Willis, Yun She, Sukanya Suresh, William R. Thompson, Clinton T. Rubin, Khalid S. Mohammad, Theresa A. Guise
Publikováno v:
bioRxiv
Combination treatment of Low-Intensity Vibration (LIV) with zoledronic acid (ZA) was hypothesized to preserve bone mass and muscle strength while reducing adipose tissue accrual associated with complete estrogen (E2)-deprivation in young and skeletal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec43956c074715b41cab60f3b02bcf4c
https://doi.org/10.1101/2023.03.12.531571
https://doi.org/10.1101/2023.03.12.531571
Autor:
Jing Fu, Shirong Li, Huihui Ma, Jun Yang, Lewis M Brown, Gabriel M. Pagnotti, Stephen J. Weiss, Markus Y. Mapara, Suzanne Lentzsch
Publikováno v:
Blood. 140:9930-9932
Autor:
Clinton T. Rubin, Maya Styner, Eric L. Klett, Sarah E. Little-Letsinger, Gabriel M. Pagnotti, Cody McGrath, Janet Rubin, Brian O. Diekman
Publikováno v:
Seminars in Cell & Developmental Biology. 123:22-35
Aging induces alterations in bone structure and strength through a multitude of processes, exacerbating common aging- related diseases like osteoporosis and osteoarthritis. Cellular hallmarks of aging are examined, as related to bone and the marrow m