Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gabriel M. C. Longo"'
Autor:
Ning Zhang, Luuk Harbers, Michele Simonetti, Constantin Diekmann, Quentin Verron, Enrico Berrino, Sara E. Bellomo, Gabriel M. C. Longo, Michael Ratz, Niklas Schultz, Firas Tarish, Peng Su, Bo Han, Wanzhong Wang, Sofia Onorato, Dora Grassini, Roberto Ballarino, Silvia Giordano, Qifeng Yang, Anna Sapino, Jonas Frisén, Kanar Alkass, Henrik Druid, Vassilis Roukos, Thomas Helleday, Caterina Marchiò, Magda Bienko, Nicola Crosetto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Somatic copy number alterations (SCNAs) are pervasive in advanced human cancers, but their prevalence and spatial distribution in early-stage, localized tumors and their surrounding normal tissues are poorly characterized. Here, we perform m
Externí odkaz:
https://doaj.org/article/a7bc352b5e9d473f9b3b201fba7c47d9
Autor:
Thorsten Mosler, Francesca Conte, Gabriel M. C. Longo, Ivan Mikicic, Nastasja Kreim, Martin M. Möckel, Giuseppe Petrosino, Johanna Flach, Joan Barau, Brian Luke, Vassilis Roukos, Petra Beli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Transcription can pose a threat to genomic instability through the formation of R-loops, which are RNA–DNA hybrids with a displaced non-template DNA strand. Here the authors mapped the R-loop proximal proteome in human cells and identified a role o
Externí odkaz:
https://doaj.org/article/05bb324df10645da96b7973878aa788d
Autor:
Qifeng Yang, Thomas Helleday, Vassilis Roukos, Firas Tarish, Wanzhong Wang, Gabriel M C Longo, Caterina Marchiò, Sofia Onorato, Peng Su, Bo Han, Michele Simonetti, Niklas Schultz, Ning Zhang, Magda Bienko, Enrico Berrino, Nicola Crosetto, Luuk Harbers
Copy number alterations (CNAs) are pervasive in advanced human cancers, but their prevalence in early-stage, localized tumors and their surrounding normal tissues is poorly characterized. To investigate this phenomenon, here we developed a method for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07da9e13a352b8d97baf5bcc028ab8a4
https://doi.org/10.21203/rs.3.rs-1093341/v1
https://doi.org/10.21203/rs.3.rs-1093341/v1
Autor:
Gabriel M C, Longo, Vassilis, Roukos
Publikováno v:
Nature reviews. Molecular cell biologyOriginal articles. 22(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65f3657a8c0c853d2b427df15f935065
https://pubmed.ncbi.nlm.nih.gov/33854243
https://pubmed.ncbi.nlm.nih.gov/33854243
Single-cell analysis of structural variations and complex rearrangements with tri-channel processing
Autor:
David Porubsky, Ashley D. Sanders, Martin Schrappe, Tobias Rausch, Jan O. Korbel, Beat Bornhauser, Joachim B. Kunz, Andreas E. Kulozik, Tobias Marschall, Benjamin Raeder, Davide Bolognini, Juergen Zimmermann, Balca R. Mardin, M. Alexandra C. C. van Vliet, Vladimir Benes, Hyobin Jeong, Maryam Ghareghani, Venla Kinanen, Jean-Pierre Bourquin, Paulina Richter-Pechanska, Sascha Meiers, Silvia Jenni, Gabriel M. C. Longo
Publikováno v:
Nature Biotechnology
Nat Biotechnol
Nat Biotechnol
Structural variation (SV), involving deletions, duplications, inversions and translocations of DNA segments, is a major source of genetic variability in somatic cells and can dysregulate cancer-related pathways. However, discovering somatic SVs in si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce3b7fcb7277706b2745924f126bb96