Clinical phenotypes and quality of life to define post-COVID-19 syndrome: a cluster analysis of the multinational, prospective ORCHESTRA cohortResearch in context

Autor: Elisa Gentilotti, Anna Górska, Adriana Tami, Roy Gusinow, Massimo Mirandola, Jesús Rodríguez Baño, Zaira R. Palacios Baena, Elisa Rossi, Jan Hasenauer, Iris Lopes-Rafegas, Elda Righi, Natascia Caroccia, Salvatore Cataudella, Zeno Pasquini, Thomas Osmo, Lidia Del Piccolo, Alessia Savoldi, Samir Kumar-Singh, Fulvia Mazzaferri, Maria Giulia Caponcello, Gerolf de Boer, Gabriel Levy Hara, Pasquale De Nardo, Surbhi Malhotra, Lorenzo Maria Canziani, Jade Ghosn, Aline-Marie Florence, Nadhem Lafhej, Bernardina T.F. van der Gun, Maddalena Giannella, Cédric Laouénan, Evelina Tacconelli, Mariana Nunes Pinho Guedes, Gaia Maccarrone, Maria Diletta Pezzani, Marcella Sibani, Ruth Joanna Davies, Stefania Vitali, Giorgia Franchina, Giorgia Tomassini, Concetta Sciammarella, Riccardo Cecchetto, Davide Gibellini, Chiara Konishi De Toffoli, Giulia Rosini, Chiara Perlini, Marco Meroi, Filippo Cioli Puviani, Daniele Fasan, Claudio Micheletto, Stefania Montemezzi, Nicolò Cardobi, Gianluca Vantini, Gloria Mazzali, Giovanni Stabile, Maddalena Marcanti, Marco Pattaro Zonta, Deborah Calì, Anna Mason, Cinzia Perlini, Paolo Gisondi, Maria Mongardi, Simona Sorbello, Karin I. Wold, María F. Vincenti-González, Alida C.M. Veloo, Valerie P.R. Harmsma, Daniele Pantano, Margriet van der Meer, Lilli Gard, Erley F. Lizarazo, Marjolein Knoester, Alex W. Friedrich, Hubert G.M. Niesters, Pierluigi Viale, Domenico Marzolla, Federica Cosentino, Michela Di Chiara, Giacomo Fornaro, Cecilia Bonazzetti, Beatrice Tazza, Alice Toschi, Oana Vetamanu, Maria Eugenia Giacomini, Fabio Trapani, Lorenzo Marconi, Luciano Attard, Sara Tedeschi, Liliana Gabrielli, Tiziana Lazzarotto, Paula Olivares, Javier Castilla, Javier Vélez, Virginia Almadana, Lucía Martín-Barrera, Ana Belén Martín-Gutiérrez, David Gutiérrez-Campos, Marta Fernández-Regaña, Ana Silva-Campos, Patricia Fernández-Riejos, M. Isabel García-Sánchez, Carla V. Giuliano, Carlota López, Gabriela Neumann, Julieta Camporro, Lautaro de Vedia, Hugo Agugliaro, Gabriella Scipione, Chiara Dellacasa, Balasubramanian Chandramouli, Silvia Gioiosa, Juan Mata Naranjo, Maurizio Ortali, Angelina Konnova, Akshita Gupta, Mathias Smet, An Hotterbeekx, Matilda Berkell, Elisa Sicuri, Delphine Bachelet, Lila Bouadma, Minerva Cervantes-Gonzalez, Anissa Chair, Charlotte Charpentier, Léo Chenard, Diane Descamps, Hang Doan, Xavier Duval, Marina Esposito-Farese, Isabelle Hoffmann, Ouifiya Kafif, Quentin Le Hingrat, Sophie Letrou, France Mentré, Marion Schneider, Coralie Tardivon, Jean-Francois Timsit, Sarah Tubiana, Amal Abrous, Sandrine Couffin-Cadiergues, Fernanda Dias Da Silva, Hélène Esperou, Ikram Houas, Salma Jaafoura, Aurélie Papadopoulos, Severine Ansart, Adrien Auvet, Firouzé Bani-Sadr, L. Bernard, François Bissuel, Elisabeth Botelho-Nevers, Damien Bouhour, André Cabié, Pauline Caraux Paz, Christian Chidiac, Catherine Chirouze, Tomasz Chroboczek, Hugues Cordel, Roxane Courtois, Nathalie De Castro, Sylvain Diamamntis, Jean-Luc Diehl, Felix Djossou, Céline Dorival, Olivier Epaulard, Valerie Gaborieau, François Goehringer, Marie Gousseff, Simon Jamard, Cedric Joseph, Karine Lacombe, Soizic Le Mestre, Vincent Le Moing, Jean-Daniel Lelievre, Olivier Lesens, M. Machado, Mylène Maillet, Victoria Manda, Guillaume Martin-Blondel, Martin Martinot, Vanina Meysonnier, Jean-Michel Molina, Eric Oziol, Vincent Pestre, Lionel Piroth, Julien Poissy, Christian Rabaud, François Raffi, Blandine Rammaert, Christophe Rapp, Stanislas Rebaudet, Pierre-Marie Roger, Damien Roux, Eric Senneville, Pierre Tattevin, Aurélie Wiedemann, David Zucman

Publikováno v: EClinicalMedicine, Vol 62, Iss , Pp 102107- (2023)

Summary: Background: Lack of specific definitions of clinical characteristics, disease severity, and risk and preventive factors of post-COVID-19 syndrome (PCS) severely impacts research and discovery of new preventive and therapeutics drugs. Methods

Externí odkaz: https://doaj.org/article/22600d8ef9254da88af1d1e9de66fe78

SARS-CoV-2 mRNA Vaccine Response in People Living with HIV According to CD4 Count and CD4/CD8 Ratio

Autor: Alessandra Vergori, Alessandro Tavelli, Giulia Matusali, Anna Maria Azzini, Matteo Augello, Valentina Mazzotta, Giovanni Francesco Pellicanò, Andrea Costantini, Antonio Cascio, Andrea De Vito, Lorenzo Marconi, Elda Righi, Assunta Sartor, Carmela Pinnetti, Fabrizio Maggi, Francesca Bai, Simone Lanini, Stefania Piconi, Gabriel Levy Hara, Giulia Marchetti, Maddalena Giannella, Evelina Tacconelli, Antonella d’Arminio Monforte, Andrea Antinori, Alessandro Cozzi-Lepri, on behalf of the Vax-ICONA-ORCHESTRA Study

Publikováno v: Vaccines, Vol 11, Iss 11, p 1664 (2023)

Background: Our aim was to estimate the rates of not achieving a robust/above-average humoral response to the COVID-19 mRNA vaccine in people living with HIV (PLWH) who received ≥2 doses and to investigate the role of the CD4 and CD4/CD8 ratio in p

Externí odkaz: https://doaj.org/article/dfc19fae67334a88af68e14c0363fa5b

Immunoglobulin Heavy Chain High-Throughput Sequencing in Pediatric B-Precursor Acute Lymphoblastic Leukemia: Is the Clonality of the Disease at Diagnosis Related to Its Prognosis?

Autor: Gabriel Levy, Michal Kicinski, Jona Van der Straeten, Anne Uyttebroeck, Alina Ferster, Barbara De Moerloose, Marie-Francoise Dresse, Christophe Chantrain, Bénédicte Brichard, Marleen Bakkus

Publikováno v: Frontiers in Pediatrics, Vol 10 (2022)

High-throughput sequencing (HTS) of the immunoglobulin heavy chain (IgH) locus is a recent very efficient technique to monitor minimal residual disease of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). It also reveals the sequences of clona

Externí odkaz: https://doaj.org/article/1e1f159978f84aa9badee8da0e72d0e9

A one health framework to estimate the cost of antimicrobial resistance

Autor: Chantal M. Morel, Richard A. Alm, Christine Årdal, Alessandra Bandera, Giacomo M. Bruno, Elena Carrara, Giorgio L. Colombo, Marlieke E. A. de Kraker, Sabiha Essack, Isabel Frost, Bruno Gonzalez-Zorn, Herman Goossens, Luca Guardabassi, Stephan Harbarth, Peter S. Jørgensen, Souha S. Kanj, Tomislav Kostyanev, Ramanan Laxminarayan, Finola Leonard, Gabriel Levy Hara, Marc Mendelson, Malgorzata Mikulska, Nico T. Mutters, Kevin Outterson, Jesus Rodriguez Baňo, Evelina Tacconelli, Luigia Scudeller, the GAP-ON€ network

Publikováno v: Antimicrobial Resistance and Infection Control, Vol 9, Iss 1, Pp 1-14 (2020)

Abstract Objectives/purpose The costs attributable to antimicrobial resistance (AMR) remain theoretical and largely unspecified. Current figures fail to capture the full health and economic burden caused by AMR across human, animal, and environmental

Externí odkaz: https://doaj.org/article/dc4a2198b87d4b42aacdc8e28e00a7d0

Uses and misuses of the sedimentation sign in lumbar spine stenosis.

Autor: Gabriel Levy, Constantin Schizas

Publikováno v: Brain and Spine, Vol 2, Iss , Pp 101676- (2022)

Externí odkaz: https://doaj.org/article/f36a9c5e05d8415a95a4ddbce42f18df