Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Gabriel L. Plaa"'
Publikováno v:
Liver. 15:271-275
The importance of the bioactivation of 1-naphthylisothiocyanate was studied. Forty minutes after 1-naphthylisothiocyanate administration to rats, bile was collected over a 2.5-h period; the liver was then excised and homogenized. 1-naphthylisothiocya
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e3deadecdb8da925b4289fba4fde43
https://doi.org/10.1111/j.1600-0676.1995.tb00684.x
https://doi.org/10.1111/j.1600-0676.1995.tb00684.x
Publikováno v:
Toxicological Sciences. 73:378-385
Manganese (Mn) and bilirubin (BR) induce intrahepatic cholestasis when injected sequentially. It was suggested that accumulation of newly synthesized cholesterol in the canalicular membrane is an initial step in the development of cholestasis. To cla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b1a1aab91a6287d2907186ff5b3bd5
https://doi.org/10.1093/toxsci/kfg054
https://doi.org/10.1093/toxsci/kfg054
Publikováno v:
Toxicological Sciences. 53:150-155
Manganese-bilirubin (Mn-BR)-induced cholestasis in rats is associated with altered lipid composition of various hepatic subcellular fractions. Increased bile canalicular (BCM) cholesterol content in Mn-BR cholestasis and the intracellular source of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d24d03b80f96e8e2365701a9db4b67
https://doi.org/10.1093/toxsci/53.1.150
https://doi.org/10.1093/toxsci/53.1.150
Publikováno v:
Toxicological Sciences. 45:242-246
We assessed the effects of dexamethasone on functional and histological changes after acute exposure to a high level of chlorine gas in an animal model of reactive airways dysfunction syndrome (RADS). Sprague-Dawley male rats were exposed to 1500 ppm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89aadc1ce0a9f202432f105ca19fa9d0
https://doi.org/10.1093/toxsci/45.2.242
https://doi.org/10.1093/toxsci/45.2.242
Autor:
Pierre Raymond, Gabriel L. Plaa
Publikováno v:
Journal of Toxicology and Environmental Health. 51:463-476
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6043071e17de176c68bc4056007ddca1
https://doi.org/10.1080/009841097159917
https://doi.org/10.1080/009841097159917
Publikováno v:
Journal of Toxicology and Environmental Health Part A. 49:285-300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f609a10d722115ab12b0e841e441ede
https://doi.org/10.1080/009841096160835
https://doi.org/10.1080/009841096160835
Ketone potentiation of haloalkane‐induced hepato‐ and nephrotoxicity. I. dose‐response relationships
Autor:
Pierre Raymond, Gabriel L. Plaa
Publikováno v:
Journal of Toxicology and Environmental Health. 45:465-480
Carbon tetrachloride (CCl4) induced hepatotoxicity and chloroform (CHCl3) induced nephrotoxicity were evaluated in male Sprague-Dawley rats pretreated with acetone (A), methyl ethyl ketone (MEK), and methyl isobutyl ketone (MiBK). Dose-response relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2a5516d536def20aefaa07f6737ea1
https://doi.org/10.1080/15287399509532009
https://doi.org/10.1080/15287399509532009
Publikováno v:
Hepatology. 21:1038-1044
Metallothionein (MT) is a small cysteine-rich protein thought to be mainly involved in metal regulation and detoxification. The implication of MT in cell growth and differentiation has also been suggested. This latter hypothesis was further investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2582527d28a96ac418b88103af79cd29
https://doi.org/10.1016/0270-9139(95)90252-x
https://doi.org/10.1016/0270-9139(95)90252-x
Publikováno v:
Hepatology. 21:1038-1044
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4a12ac149474607ac09d7d5226b4408
https://doi.org/10.1002/hep.1840210423
https://doi.org/10.1002/hep.1840210423
Publikováno v:
Toxicology Letters. 70:263-267
The metabolic fate of methyl n-butyl ketone (MnBK) and its isomer methyl isobutyl ketone (MiBK) was studied in mice. The concentrations of both ketones and their metabolites in blood and brain were measured at different time intervals after their adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43dd8e2bbddc92fcf5198d5058cbf1b
https://doi.org/10.1016/0378-4274(94)90120-1
https://doi.org/10.1016/0378-4274(94)90120-1