Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Gabriel L, Fiszman"'
Autor:
Estefanía S. Peri Ibáñez, Agostina Mazzeo, Carolina Silva, Maria Juliana Juncos, Guadalupe S. Costa Navarro, Horacio M. Pallarés, Virginia J. Wolos, Gabriel L. Fiszman, Silvia L. Mundo, Julio J. Caramelo, Marcelo J. Yanovsky, Matías Fingermann, Alejandro A. Castello, Andrea V. Gamarnik, Ana S. Peinetti, Daiana A. Capdevila
Publikováno v:
Biosensors, Vol 14, Iss 9, p 416 (2024)
The COVID-19 pandemic highlighted testing inequities in developing countries. Lack of lateral flow test (LFT) manufacturing capacity was a major COVID-19 response bottleneck in low- and middle-income regions. Here we report the development of an open
Externí odkaz:
https://doaj.org/article/9dc9f3d5a6334918b0ec18dc478aff3f
Autor:
Cristina E Rodríguez, Sara I Reidel, Elisa D Bal de Kier Joffé, Maria A Jasnis, Gabriel L Fiszman
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137920 (2015)
Multicellular tumor spheroids represent a 3D in vitro model that mimics solid tumor essential properties including assembly and development of extracellular matrix and nutrient, oxygen and proliferation gradients. In the present study, we analyze the
Externí odkaz:
https://doaj.org/article/35a404a3c41846ec9c8f2e29ee2440da
Autor:
María Gabriela Lombardi, María Pía Negroni, Laura Tatiana Pelegrina, María Ester Castro, Gabriel L Fiszman, María Eugenia Azar, Carlos Cresta Morgado, María Elena Sales
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57572 (2013)
The presence of autoantibodies in cancer has become relevant in recent years. We demonstrated that autoantibodies purified from the sera of breast cancer patients activate muscarinic acetylcholine receptors in tumor cells. Immunoglobulin G (IgG) from
Externí odkaz:
https://doaj.org/article/926c78063f4f4edeb9a243b4a9a2b221
Autor:
Gabriel L. Fiszman, María A. Jasnis
Publikováno v:
International Journal of Breast Cancer, Vol 2011 (2011)
The epidermal growth factor receptor 2 (HER2) is a tyrosine kinase overexpressed in nearly 20% to 25% of invasive breast cancers. Trastuzumab is a humanized monoclonal antibody that targets HER2. The majority of patients with metastatic breast cancer
Externí odkaz:
https://doaj.org/article/5df84d1599804d1ab40c36069f7aac39
Autor:
Ezequiel Lacunza, Virginia Judith Wolos, Gabriel L. Fiszman, Ivana Jaqueline Tapia, Elisa Bal de Kier Joffé, Marianela Abrigo
Publikováno v:
Cancer Research. 81:1078-1078
Trastuzumab and trastuzumab emtansine (T-DM1) targeted therapies are the main choice for the treatment of HER2-overexpressing breast cancer patients. However, de novo or acquired resistance is still the major obstacle in clinical practice. It has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f4b0b48b2e590e4c437cd75a720ab95
https://doi.org/10.1158/1538-7445.am2021-1078
https://doi.org/10.1158/1538-7445.am2021-1078
Autor:
Damian E. Berardi, Laura B. Todaro, Cristina E. Rodríguez, Marianela Abrigo, Elisa Bal de Kier Joffé, Gabriel L. Fiszman
Publikováno v:
Journal of Cellular Biochemistry. 119:1381-1391
Breast cancer human cells culture as spheroids develop autophagy and apoptosis, which promotes Trastuzumab resistance in HER2 overexpressing cells. Our aim was to study the association of the hostile environment developed in 3D with the breast cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a65a89d4756114c8a1e73e7bcab1b5
https://doi.org/10.1002/jcb.26298
https://doi.org/10.1002/jcb.26298
Autor:
Alejandro J. Urtreger, Damian E. Berardi, Laura B. Todaro, Elisa Bal de Kier Joffé, Gabriel L. Fiszman, Stefano M. Cirigliano, María I. Díaz Bessone, Cristina E. Rodríguez, Carolina Flumian
Publikováno v:
Journal of Cellular Biochemistry. 117:730-740
Protein kinase C (PKC) is a family of serine/threonine kinases that regulate diverse cellular functions including cell death, proliferation, and survival. Recent studies have reported that PKCδ, are involved in apoptosis or autophagy induction. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4e639ed7d069321748967b39b8d3a8a
https://doi.org/10.1002/jcb.25358
https://doi.org/10.1002/jcb.25358
Autor:
Silvia Vanzulli, Ximena Borenstein, Gabriel L. Fiszman, Maria A. Jasnis, Ada Gabriela Blidner
Publikováno v:
Nitric Oxide. 23:234-241
Low O(2) levels in solid tumors are associated with increase in hypoxia-inducible factor 1alpha (HIF-1alpha). The present study examines functional changes involved in adaptation to hypoxia of the LMM3 mammary tumor cell line, using CoCl(2) as hypoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982adbfda8d5a78f624787a2da8f9769
https://doi.org/10.1016/j.niox.2010.07.003
https://doi.org/10.1016/j.niox.2010.07.003
Autor:
Liliana Maria Elena Finocchiaro, N A Altamirano, Gerardo Claudio Glikin, Marcela Solange Villaverde, Gabriel L. Fiszman, María L. Gil-Cardeza, R A Cwirenbaum
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
To validate the use of multicellular spheroids to predict the efficacy of herpes simplex thymidine kinase/ganciclovir (HSVtk/GCV) suicide gene therapy in the respective in vivo tumors, we established and characterized 15 melanoma-derived cell lines f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c009290dc635fab4335526bc9aec98
https://doi.org/10.1038/gt.2009.107
https://doi.org/10.1038/gt.2009.107
Autor:
María Elena Sales, Mariana Farina, Alejandro Español, Eulalia de la Torre, Gabriel L. Fiszman, María C Middonno
Publikováno v:
Cancer Biology & Therapy. 6:1106-1113
Muscarinic acetylcholine receptors (mAChR) are members of the G-protein coupled receptor family. These receptors play key physiological roles and changes in their expression and/or function are involved in several diseases. We had previously demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff80601e4763de487b506c9c5d6b7e3
https://doi.org/10.4161/cbt.6.7.4330
https://doi.org/10.4161/cbt.6.7.4330