Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gabriel Gracia-Maldonado"'
Autor:
Gabriel Gracia-Maldonado, Jason Clark, Matthew Burwinkel, Brenay Greenslade, Mark Wunderlich, Nathan Salomonis, Dario Leone, Evelina Gatti, Philippe Pierre, Ashish R. Kumar, Lynn H. Lee
Publikováno v:
Haematologica, Vol 107, Iss 4 (2021)
Although great advances have been made in understanding the pathobiology of mixed lineage leukemia-rearranged (MLL-r) leukemias, therapies for this leukemia have remained limited, and clinical outcomes remain bleak. In order to identify novel targets
Externí odkaz:
https://doaj.org/article/3a5c9617d03f4777999cbd2fb6ef2278
Autor:
Mark Wunderlich, Brenay Greenslade, Matthew Burwinkel, Lynn Lee, Gabriel Gracia-Maldonado, Philippe Pierre, Jason Clark, Ashish R Kumar, Evelina Gatti, Dario Leone, Nathan Salomonis
Publikováno v:
Haematologica
Haematologica, 2020, ⟨10.3324/haematol.2020.257451⟩
Haematologica, Ferrata Storti Foundation, 2020, ⟨10.3324/haematol.2020.257451⟩
Haematologica, 2020, ⟨10.3324/haematol.2020.257451⟩
Haematologica, Ferrata Storti Foundation, 2020, ⟨10.3324/haematol.2020.257451⟩
Although great advances have been made in understanding the pathobiology of mixed lineage leukemia-rearranged (MLL-r) leukemias, therapies for this leukemia have remained limited, and clinical outcomes remain bleak. In order to identify novel targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416d2f6703a0d1a89d524c145e431438
https://hal-amu.archives-ouvertes.fr/hal-03385563
https://hal-amu.archives-ouvertes.fr/hal-03385563
Autor:
Gabriel Gracia-Maldonado, James C. Mulloy, Bruce J. Aronow, Ashish R Kumar, Mark Wunderlich, Kevin A. Link, Nupur Dasgupta, Jayeeta Roychoudhury, Zeenath Unnisa, Gang Huang, Jason Clark
Publikováno v:
Blood. 125:2544-2552
Leukemias with MLL translocations are often found in infants and are associated with poor outcomes. The pathogenesis of MLL-fusion leukemias has been linked to upregulation of HOX/MEIS1 genes. The functions of the Hox/Meis1 complex in leukemia, howev
Publikováno v:
Blood. 132:3900-3900
Introduction Chromosomal translocations involving the Mixed Lineage Leukemia (MLL, also called KMT2A) gene account for around 80% of the acute lymphoid leukemia (ALL) and 35%-50% of the acute myeloid leukemia (AML) diagnosed in infants, and are assoc
Publikováno v:
Blood. 128:1512-1512
Acute leukemias with Mixed Lineage Leukemia gene (MLL, also called KMT2A) translocations are associated with poor outcomes. These leukemias are most frequently encountered in infants and as secondary malignancies, and can be either lymphoid or myeloi