Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gabriel Goldberger"'
Publikováno v:
Gene. 208:17-24
Complement factor I is a serine proteinase that regulates the classical and alternative pathways of complement by cleaving C3b and C4b and preventing the assembly of C3 and C5 convertase enzymes. In order to understand the regulation of factor I gene
Publikováno v:
Journal of human genetics. 59(5)
Recent reviews discussed the critical roles of apoptosis in human spermatogenesis and infertility. These reviews highlight the FasL-induced caspase cascade in apoptosis lending importance to our discovery of the pseudogene status of the Lfg5 gene in
Publikováno v:
Molecular Immunology. 32:379-387
Factor I is an active serine proteinase in plasma that regulates both the classical and alternative complement pathways by cleaving C3b and C4b thereby preventing the assembly of C3 and C5 convertase enzymes. In this study, a full-length human factor
Publikováno v:
Apoptosis : an international journal on programmed cell death. 14(11)
The expanding wealth of human, model and other organism’s genomic data has allowed the identification of a distinct gene family of apoptotic related genes. Most of these genes are currently unannotated or have been subsumed under two questionably r
Autor:
Lisa M. Kunnath-Muglia, Joe O. Minta, Gabriel Goldberger, Michael J. Wong, Christine A. Kozak
Publikováno v:
Molecular immunology. 33(1)
Factor I is an essential regulatory serine proteinase of the complement cascade. It cleaves and inactivates the C3b and C4b constituents of the C3 and C5 convertases and thereby regulates many complement-mediated activities. The human proteins is a h
Publikováno v:
International Union of Biochemistry and Molecular Biology: Life. 48:469-470
The gene sequence encoding the non-catalytic heavy chain of mouse complement factor I (mCFI) was cloned and its exon-intron organization and domain structure characterized. The genomic organization of mCFI differs in several aspects from its human ho
Autor:
Harvey R. Colten, Gabriel Goldberger
Publikováno v:
Pediatrics. 64:775-780
The capacity for complement biosynthesis appears early in gestation. In most species, functional complement and properdin systems are intact by the end of the first trimester. An increase in fetal serum complement concentration (several components) o
Autor:
Harvey R. Colten, M. D. Edge, Jean D. Sipe, Alexander S. Whitehead, A. S. Cohen, Gabriel Goldberger, Brian F. Tack
Publikováno v:
Biochemistry. 24:2931-2936
To study structural variants of human serum amyloid A (SAA), an apoprotein of high-density lipoprotein, complementary DNA clones were isolated from a human liver library with the use of two synthetic oligonucleotide mixtures containing sequences that
Autor:
Alexander S. Whitehead, Gabriel Goldberger, Derek E. Woods, Alexander F. Markham, Harvey R. Colten
Publikováno v:
Proceedings of the National Academy of Sciences. 80:5387-5391
A cDNA clone for the fourth complement component (C4), pC4AL1, has been isolated from a human adult liver cDNA library by using a synthetic oligonucleotide mixture containing all 384 possible sequences coding for residues 14-21 of the C4 gamma-chain
Publikováno v:
Molecular Immunology. 23:1263-1266