Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gabriel G. Perrone"'
Autor:
Moufid El-Khoury, Rogine Ligot, Simon Mahoney, Colin M. Stack, Gabriel G. Perrone, C. Oliver Morton
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Abstract Objective Recent studies into the antifungal activity of NK-cells against the Aspergillus fumigatus have presented differing accounts on their mode of antifungal activity. One of these mechanisms proposed that NK-cells may kill the fungus vi
Externí odkaz:
https://doaj.org/article/54f85b4bb5b14f48b59974a64255c03f
Autor:
Gayani Petersingham, Ming J. Wu, Gabriel G. Perrone, Patrick J. O'Doherty, Mark P. Molloy, Filip Veljanoski, Suhua Li, Alex A. Phrakaysone, Mohammad S. Zaman, Adam J. Johnson
Publikováno v:
Metallomics. 9:301-308
Metal ions, biologically essential or toxic, are present in the surrounding environment of living organisms. Understanding their uptake, homeostasis or detoxification is critical in cell biology and human health. In this study, we investigated the ro
Autor:
Ian W. Dawes, Gabriel G. Perrone
Publikováno v:
FEMS yeast research. 20(1)
There has long been speculation about the role of various stresses in ageing. Some stresses have beneficial effects on ageing—dependent on duration and severity of the stress, others have negative effects and the question arises whether these negat
Autor:
Antonio Lauto, Andrew J. Ruys, Christian Pedrinazzi, Jessica Houang, Leonardo Longo, Gabriel G. Perrone, Damia Mawad, Philip Boughton
Publikováno v:
Photonic Diagnosis and Treatment of Infections and Inflammatory Diseases II.
The clinical use of photodynamic therapy (PDT) with rose bengal (RB) is emerging as an effective t reatment for a range of applications given its non-invasive and localised mode of delivery. In particular, rose bengal PDT has shown promising antifung
Autor:
Gabriel G. Perrone, Rogine Ligot, Moufid El-Khoury, C. Oliver Morton, Simon Mahoney, Colin M. Stack
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
BMC Research Notes, Vol 10, Iss 1, Pp 1-6 (2017)
Objective Recent studies into the antifungal activity of NK-cells against the Aspergillus fumigatus have presented differing accounts on their mode of antifungal activity. One of these mechanisms proposed that NK-cells may kill the fungus via the dir
Autor:
Alex A. Phrakaysone, Allison C. Gee, Stefanie Jarolim, Michael Breitenbach, Ian W. Dawes, Bethany Pillay, Anita Ayer, Gabriel G. Perrone
Publikováno v:
G3: Genes|Genomes|Genetics
The heat-shock response in cells, involving increased transcription of a specific set of genes in response to a sudden increase in temperature, is a highly conserved biological response occurring in all organisms. Despite considerable attention to th
Autor:
Anita Ayer, Gabriel G. Perrone, Ian W. Dawes, Andreas J. Meyer, Shi-Xiong Tan, Chris M. Grant
Publikováno v:
Free Radical Biology and Medicine. 49:1956-1968
Glutathione (GSH) is a key redox buffer and protectant. Growth (approx. one or two divisions) of cells lacking γ-glutamylcysteine synthetase (gsh1) in the absence of GSH led to irreversible respiratory incompetency in all cells, and after five divis
Autor:
Philip Boughton, Leonardo Longo, Damia Mawad, Andrew J. Ruys, Christian Pedrinazzi, Antonio Lauto, Jessica Houang, Gabriel G. Perrone
Publikováno v:
Advanced Therapeutics. 2:1800105
Autor:
Sebastian Raeth, Gabriel G. Perrone, Darren Greetham, Chris M. Grant, Ian W. Dawes, Shi-Xiong Tan
Publikováno v:
Journal of Biological Chemistry. 285:6118-6126
Cellular mechanisms that maintain redox homeostasis are crucial, providing buffering against oxidative stress. Glutathione, the most abundant low molecular weight thiol, is considered the major cellular redox buffer in most cells. To better understan
Autor:
Jessica Houang, Damia Mawad, Andrew J. Ruys, Philip Boughton, Gabriel G. Perrone, Antonio Lauto
Publikováno v:
Journal of Biophotonics. 11:e201700350
Nail fungal infections are notoriously persistent and difficult to treat which can lead to severe health impacts, particularly in the immunocompromized. Current antifungal treatments, including systemic and topical drugs, are prolonged and do not eff