Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gabriel E. Job"'
Autor:
Rongliang Lou, Jacek Martynow, Maxwell M. Reeve, Roger Hanselmann, Graham Johnson, Gabriel E. Job
Publikováno v:
Organic Process Research & Development. 14:152-158
The copper-catalyzed “click” reaction of an azide with an alkyne has become a popular method to build up 1,4-substituted 1H-1,2,3-triazoles in medicinal chemistry and this approach was used on a laboratory scale during the preparation of novel ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::368a6e7f7bfba83eaeeae38fc0ed43fb
https://doi.org/10.1021/op900252a
https://doi.org/10.1021/op900252a
Autor:
Nobuyuki Harada, Masataka Watanabe, Yusuke Kasai, Alex Shvets, William H. Pirkle, Masashi Kosaka, Kaori Fujita, Gabriel E. Job, Shunsuke Kuwahara, Hiromi Taji
Publikováno v:
Journal of Chromatography A. 1055:41-53
Members of a series of diarylmethanols, diarylmethyl pivalates, and diarylmethyl acetates (analyte sets 1-26) were enantioresolved with the (S,S)-Whelk-O1 chiral stationary phase (CSP). An analogue of the (S,S)-Whelk-O1 selector was combined with ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4007eace2017a560861125c121267737
https://doi.org/10.1016/j.chroma.2004.08.001
https://doi.org/10.1016/j.chroma.2004.08.001
Publikováno v:
Angewandte Chemie International Edition. 43:5649-5651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356d73d2640ba0d4d7afa033c17b9dd1
https://doi.org/10.1002/anie.200460536
https://doi.org/10.1002/anie.200460536
Publikováno v:
ChemInform. 33
A simple and mild method for the coupling of aryl iodides and aliphatic alcohols that does not require the use of alkoxide bases is described. The reactions can be performed in neat alcohol. For more precious alcohols, the etherification was carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d720b85814727d3ef7e44840dbe9254d
https://doi.org/10.1002/chin.200235085
https://doi.org/10.1002/chin.200235085
Autor:
Sharon M. Walker, Gabriel E. Job, Justin S. Miller, Daniel S. Kemp, Björn Heitmann, Robert J. Kennedy
Publikováno v:
Journal of the American Chemical Society. 128(25)
Length-dependent helical propensities w(Ala)(n,T) at T = 10, 25, and 60 degrees C are assigned from t/c values and NMR 13C chemical shifts for series 1 peptides TrpLys(m)Inp2(t)Leu-Ala(n)(t)LeuInp2Lys(m)NH2, n = 15, 19, and 25, m = 5, in water. Van't
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12af394e1bbe0260785a75e237a8672
https://pubmed.ncbi.nlm.nih.gov/16787087
https://pubmed.ncbi.nlm.nih.gov/16787087
NMR and CD studies are reported for two length series of solubilized, spaced, highly helical polyalanines that are N-capped by the optimal helix stabilizer (beta)Asp-Hel and C-capped by beta-aminoalanine beta and that are studied in water at 2 degree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c55a8291b150c5bb9ef329d03fa459b3
https://europepmc.org/articles/PMC1941670/
https://europepmc.org/articles/PMC1941670/
Publikováno v:
ChemInform. 35
[reaction: see text] A general and efficient copper-catalyzed method for the amidation of vinyl bromides and iodides has been developed. This protocol uses a combination of 5 mol % copper iodide and 20 mol % N,N'-dimethyl ethylenediamine. Substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312892ebf0cd72ef5ee5096792ddff8b
https://doi.org/10.1002/chin.200405058
https://doi.org/10.1002/chin.200405058
Autor:
Masashi Kosaka, Nobuyuki Harada, Yusuke Kasai, Gabriel E. Job, William H. Pirkle, Shunsuke Kuwahara, Takeo Sugito, Masataka Watanabe, Alex Shvet
Publikováno v:
Chirality. 15(4)
meta-Substituted diphenylmethanols were enantioresolved by the method of chiral phthalic acid yielding enantiopure alcohols. Their absolute configurations were unambiguously determined by X-ray crystallography of chiral phthalate esters and/or by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8649c781f3fa1e5d7ffba737a4054be9
https://pubmed.ncbi.nlm.nih.gov/12666239
https://pubmed.ncbi.nlm.nih.gov/12666239
Autor:
Gabriel E. Job, Stephen L. Buchwald
Publikováno v:
ChemInform. 34
[reaction: see text] Methods for synthesizing N-aryl beta-amino alcohols and O-aryl beta-amino alcohols are described. The presence of a neighboring hydroxyl or amino group, respectively, is thought to activate beta-amino alcohols toward these transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d1e2feba03f4331d1fbaa3d1cc322e
https://doi.org/10.1002/chin.200310082
https://doi.org/10.1002/chin.200310082
Autor:
Nobuyuki Harada, Masashi Kosaka, William H. Pirkle, Shunsuke Kuwahara, Masataka Watanabe, Gabriel E. Job
Publikováno v:
Enantiomer. 7(4-5)
Enantiopure (2,6-dimethylphenyl)phenylmethanol (+)-( 3 ) and analog (+)-( 4 ) were prepared and their CD spectra were found opposite to that of (2-methylphenyl)phenylmethanol ( R )-( m )-( 2 ), the absolute configuration of which was previously estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75dcb557024c5ab1f7ad549e2efee62
https://pubmed.ncbi.nlm.nih.gov/12206501
https://pubmed.ncbi.nlm.nih.gov/12206501