Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Gabriel E. Dimattia"'
Autor:
Jacob Haagsma, Bart Kolendowski, Adrian Buensuceso, Yudith Ramos Valdes, Gabriel E. DiMattia, Trevor G. Shepherd
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Ovarian high-grade serous carcinoma (HGSC) is a highly lethal malignancy for which early detection is a challenge and treatment of late-stage disease is ineffective. HGSC initiation involves exfoliation of fallopian tube epithelial (FTE) cel
Externí odkaz:
https://doaj.org/article/ad1278351c7a4573a46854595d9528d2
Autor:
Adrian Buensuceso, Jamie Lee Fritz, Olga Collins, Yudith Ramos Valdés, Matthew J. Borrelli, Gabriel E. DiMattia, Trevor G. Shepherd
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract High-grade serous ovarian cancer (HGSOC) is an aggressive malignancy often diagnosed at an advanced stage. Although most HGSOC patients respond initially to debulking surgery combined with cytotoxic chemotherapy, many ultimately relapse with
Externí odkaz:
https://doaj.org/article/e4e36f606ccc4971901404ad71543094
Autor:
Jessica G. Tong, Yudith Ramos Valdes, Milani Sivapragasam, John W. Barrett, John C. Bell, David Stojdl, Gabriel E. DiMattia, Trevor G. Shepherd
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)
Abstract Background Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heterogeneity, which can hinder successful treatment strategies. Herein, we investigated the efficacy of an emerging oncolytic, Maraba virus (MRBV), in an
Externí odkaz:
https://doaj.org/article/6a1cbebf497f445e8c0b199b1dcd720a
Autor:
Bart Kolendowski, Yudith Ramos Valdes, Hal Hirte, Hiroaki Itamochi, Wonjae Lee, Mark Carey, Trevor G. Shepherd, Gabriel E. DiMattia
Publikováno v:
Cells, Vol 9, Iss 11, p 2408 (2020)
Ovarian clear cell carcinoma (OCCC) is a rare subtype of gynecological cancer for which well-characterized and authenticated model systems are scarce. We provide an extensive characterization of ‘105C’, a cell line generated from an adenocarcinom
Externí odkaz:
https://doaj.org/article/8c7b852cf47e41318576b9c8f4297d14
Autor:
Katrien Berns, René Bernards, Mark S. Carey, Steven de Jong, Roderick L. Beijersbergen, Cor Lieftink, Christianne A.R. Lok, Gabriel E. DiMattia, Hannah Kim, Madison Bittner, Cheng-Han Lee, Amy Dawson, Joshua Hoenisch, Aleksandra Hamilton, G. Bea A. Wisman, Shang Li, Nelson K.Y. Wong, Annemiek M.C. Gennissen, E. Marielle Hijmans, Marta Llaurado Fernandez
Supplementary Data from NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::406f24a7ab0f1875c593fcfa1e71922a
https://doi.org/10.1158/1535-7163.22523481
https://doi.org/10.1158/1535-7163.22523481
Immunohistochemical scoring of cleaved caspase 3 in EOC xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41ea25701010550ef5a0b362208f7006
https://doi.org/10.1158/1541-7786.22514370
https://doi.org/10.1158/1541-7786.22514370
Single OVCAR8-STK11KO spheroid formation and growth over time as imaged by IncuCyte ZOOM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b6e53fbaefa023e1fea21d0c276c58
https://doi.org/10.1158/1541-7786.22514406
https://doi.org/10.1158/1541-7786.22514406
Overexpression of DUSP4 in FTE and EOC cells does not alter spheroid formation or viability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f3b1201461f96e0d028a9a1be3cbec
https://doi.org/10.1158/1541-7786.22514379.v1
https://doi.org/10.1158/1541-7786.22514379.v1
Autor:
Frederick A. Dick, Gabriel E. DiMattia, Larissa Litovchick, Pirunthan Perampalam, Yudith Ramos-Valdes, James MacDonald
S1. Cumulative viability score of siRNA knockdowns. S2. Spheroid morphology of control and gene knock down cells. S3. Reattachment of control and gene knockdown spheroid cells after 72 hours. S4. Relative protein expression levels of Dyrk1A and Dyrk1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b857915fc051fee607f9e791f43323
https://doi.org/10.1158/1541-7786.22511245.v1
https://doi.org/10.1158/1541-7786.22511245.v1
Autor:
Katrien Berns, René Bernards, Mark S. Carey, Steven de Jong, Roderick L. Beijersbergen, Cor Lieftink, Christianne A.R. Lok, Gabriel E. DiMattia, Hannah Kim, Madison Bittner, Cheng-Han Lee, Amy Dawson, Joshua Hoenisch, Aleksandra Hamilton, G. Bea A. Wisman, Shang Li, Nelson K.Y. Wong, Annemiek M.C. Gennissen, E. Marielle Hijmans, Marta Llaurado Fernandez
Supplementary Figure from NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463439008174d241763555338becbd6a
https://doi.org/10.1158/1535-7163.22523478.v1
https://doi.org/10.1158/1535-7163.22523478.v1