Serum potassium levels provide prognostic information in symptomatic heart failure beyond traditional clinical variables

Autor: Camila Cristiane Toledo, Pedro Vellosa Schwartzmann, Luis Miguel Silva, Gabriel daSilva Ferreira, Fernando Bianchini Cardoso, Vinicius Citelli Ribeiro, Layde Rosane Paim, Lígia M. Antunes‐Correa, Andrei Carvalho Sposito, Jose Roberto Matos Souza, Rodrigo Modolo, Wilson Nadruz, Luis Sergio Fernandes de Carvalho, Otávio R. Coelho‐Filho

Publikováno v: ESC Heart Failure, Vol 8, Iss 3, Pp 2133-2143 (2021)

Abstract Aims Despite of recent advances in the pharmacological treatment, heart failure (HF) maintains significant morbidity and mortality rates. While serum potassium disorders are common and associated with adverse outcomes, the exact recommended

Externí odkaz: https://doaj.org/article/735e99db691f4497943d69daae7001b3

Non-Targeted LC-MS/MS Assay for Screening Over 100 Lipid Mediators from ARA, EPA, and DHA in Biological Samples Based on Mass Spectral Fragmentations

Autor: Gabriel Dasilva, Silvia Muñoz, Salomé Lois, Isabel Medina

Publikováno v: Molecules, Vol 24, Iss 12, p 2276 (2019)

A non-targeted strategy to simultaneously screen for over 100 lipid mediators from ω-6 ARA and ω-3 EPA and DHA fatty acids is presented. The method based on an extensive study of fragmentation patterns obtained by SPE-LC-MS/MS analysis-provided fin

Externí odkaz: https://doaj.org/article/36cb9c5c7a674a0b92bd6291e556dd53

Targeting Hepatic Protein Carbonylation and Oxidative Stress Occurring on Diet-Induced Metabolic Diseases through the Supplementation with Fish Oils

Autor: Silvia Muñoz, Lucía Méndez, Gabriel Dasilva, Josep Lluís Torres, Sara Ramos-Romero, Marta Romeu, María Rosa Nogués, Isabel Medina

Publikováno v: Marine Drugs, Vol 16, Iss 10, p 353 (2018)

The present study addressed the ability of long-chain ω-3 polyunsaturated fatty acids (ω-3 PUFA), i.e., eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), to ameliorate liver protein damage derived from oxidative stress and induced by cons

Externí odkaz: https://doaj.org/article/6f3eaedb4a7c4acfa145b3078f7fbca7

Fish Oil Improves Pathway-Oriented Profiling of Lipid Mediators for Maintaining Metabolic Homeostasis in Adipose Tissue of Prediabetic Rats

Autor: Isabel Medina, Lucía Méndez, Sara Ramos-Romero, Marta Romeu, Gabriel Dasilva, Josep Lluís Torres, Bernat Miralles-Pérez, Salomé Lois

Publikováno v: Frontiers in Immunology
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Frontiers in Immunology, Vol 12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
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Adipose tissue is now recognized as an active organ with an important homeostatic function in glucose and lipid metabolism and the development of insulin resistance. The present research investigates the role of lipid mediators and lipid profiling fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003a6b4f91cf6221f727dbd2431532ba
http://europepmc.org/articles/PMC8097180

Relative levels of dietary EPA and DHA impact gastric oxidation and essential fatty acid uptake

Autor: Judith Storch, Matthew Boller, Gabriel Dasilva, Isabel Medina

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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8 pages, 4 figures, 1 table
Previous research showed that increasing the proportion of docosahexaenoic acid (DHA) in marine lipid supplements significantly reduces associated health benefits compared with balanced eicosapentaenoic acid (EPA):DHA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38bd4bc3607f535736dd5f61dd50feb7
https://doi.org/10.1016/j.jnutbio.2017.11.007