Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gabriel Dagotto"'
Autor:
Gabriel Dagotto, Jana L. Fisher, David Li, Zhenyu Li, Simon Jenni, Zongli Li, Lawrence J. Tartaglia, Peter Abbink, Dan H. Barouch
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101350- (2024)
Adeno-associated viruses (AAVs) are popular gene therapy delivery vectors, but their application can be limited by anti-vector immunity. Both preexisting neutralizing antibodies (NAbs) and post-administration NAbs can limit transgene expression and r
Externí odkaz:
https://doaj.org/article/bb79628a310c4d358f90adeb46aad779
Autor:
Gabriel Dagotto, John D. Ventura, David R. Martinez, Tochi Anioke, Benjamin S. Chung, Mazuba Siamatu, Julia Barrett, Jessica Miller, Alexandra Schäfer, Jingyou Yu, Lisa H. Tostanoski, Kshitij Wagh, Ralph S. Baric, Bette Korber, Dan H. Barouch
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract The COVID-19 pandemic marks the third coronavirus pandemic this century (SARS-CoV-1, MERS, SARS-CoV-2), emphasizing the need to identify and evaluate conserved immunogens for a pan-sarbecovirus vaccine. Here we investigate the potential util
Externí odkaz:
https://doaj.org/article/8c87b057ca9f4ebdbc17436e4bb7270a
Autor:
Lisa H. Tostanoski, Alex Van Ry, Alex Lee Zhu, Elyse Teow, Abishek Chandrashekar, Shivani A. Patel, Jinyan Liu, Lauren Peter, Anthony L. Cook, Jake Yalley-Ogunro, Galit Alter, Dan H. Barouch, Mark G. Lewis, Carolin Loos, Gabriel Dagotto, Jingyou Yu, Makda S. Gebre, Mehtap Cabus, Felix Nampanya, Zhenfeng Li, Renita Brown, Douglas A. Lauffenburger, Catherine Jacob-Dolan, Esther A. Bondzie, Kelvin Blade, Laurent Pessaint, Noe B. Mercado, Hanne Andersen, Katherine McMahan, Caroline Atyeo
Publikováno v:
Nature
Recent studies have reported the protective efficacy of both natural1 and vaccine-induced2–7 immunity against challenge with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus macaques. However, the importance of humoral and cel
Publikováno v:
Cell Host & Microbe
Summary The explosive spread of SARS-CoV-2 suggests that a vaccine will be required to end this global pandemic. Progress in SARS-CoV-2 vaccine development to date has been faster than for any other pathogen in history. Multiple SARS-CoV-2 vaccine ca
Autor:
John S. Burke, Noe B. Mercado, Jingyou Yu, Dan H. Barouch, Komlan Tevi, Vaneesha Ali, Shant H. Mahrokhian, Felix Nampanya, Sarah Ducat, Carly E. Starke, Ramya Nityanandam, Lisa H. Tostanoski, Blake M. Hauser, Linda M. Wrijil, Makda S. Gebre, Kathleen Busman-Sahay, Stephanie Fischinger, Dalia Benetiene, Stephen Bondoc, Maciel Porto, Cesar Piedra-Mora, Chi N. Chan, Jacob D. Estes, Jared Feldman, Frank Wegmann, Hanneke Schuitemaker, Douglas A. Lauffenburger, Mark G. Lewis, Roland Zahn, Gabriel Dagotto, Zijin Lin, Katherine McMahan, Caroline Atyeo, Laurent Pessaint, Timothy M. Caradonna, Galit Alter, Carolin Loos, Michael Nekorchuk, Catherine Jacob-Dolan, Esther A. Bondzie, Jerome Custers, Aaron G. Schmidt, Amanda J. Martinot, Hanne Leth Andersen
Publikováno v:
Nature Medicine
Coronavirus disease 2019 (COVID-19) in humans is often a clinically mild illness, but some individuals develop severe pneumonia, respiratory failure and death1–4. Studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Autor:
Roland Zahn, Mark J. G. Bakkers, Ralph S. Baric, Laurent Pessaint, Timothy M. Caradonna, Galit Alter, Ted Kwaks, John S. Burke, Mathai Mammen, Jingyou Yu, Johan Van Hoof, Bing Chen, Marinela Kirilova, Alex Van Ry, Joseph P. Nkolola, Lisa H. Tostanoski, Johannes P. M. Langedijk, Shivani A. Patel, Shant H. Mahrokhian, Carolin Loos, Kelvin Blade, Makda S. Gebre, Lauren Peter, Katherine McMahan, Douglas A. Lauffenburger, Caroline Atyeo, Rinke Bos, Felix Nampanya, Zhenfeng Li, John D. Ventura, Noe B. Mercado, David R. Martinez, Renita Brown, Catherine Jacob-Dolan, Esther A. Bondzie, Amanda Strasbaugh, Blake M. Hauser, Huahua Wan, Elyse Teow, Hanne Andersen, Jinyan Liu, Frank Wegmann, Jerome Custers, Mark G. Lewis, Ramya Nityanandam, Anthony L. Cook, Danielle van Manen, Aaron G. Schmidt, Stephanie Fischinger, Mehtap Cabus, Gabriel Dagotto, Lucy Rutten, Lori F. Maxfield, Zijin Lin, Sietske K. Rosendahl Huber, Hanneke Schuitemaker, Paul Stoffels, Abishek Chandrashekar, Dan H. Barouch, Jared Feldman, David Zuijdgeest, Xuan He, Serge Zouantchangadou, Kaylee Verrington, Yongfei Cai, Emily Hoffman, Jort Vellinga, R. Keith Reeves
Publikováno v:
Nature
A safe and effective vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be required to end the coronavirus disease 2019 (COVID-19) pandemic1-8. For global deployment and pandemic control, a vaccine that requires only a singl
Publikováno v:
Genetics. 212:1163-1179
Malassezia are a monophyletic phylum of 18 species of commensal/ pathogenic yeasts that are prominent in the mammalian mycobiome, and recently linked to risk of Crohn’s Disease. Malassezia are challenging to study... Malassezia encompasses a monoph
Autor:
Gabriel Dagotto, Yixuan J. Hou, Ralph S. Baric, Joseph P. Nkolola, Robert H. Carnahan, David R. Martinez, Noe B. Mercado, James E. Crowe, Dan H. Barouch
Publikováno v:
Journal of Virology
Developing therapeutic and prophylactic countermeasures for the SARS-CoV-2 virus is a public health priority. During challenge studies, respiratory viruses are delivered and sampled from the same anatomical location.
Respiratory virus challenge
Respiratory virus challenge
Autor:
Lisa H. Tostanoski, Anthony L. Cook, Lori F. Maxfield, Hanneke Schuitemaker, Joseph P. Nkolola, Marinela Kirilova, Hanne Leth Andersen, John S. Burke, Jerome Custers, Kelvin Blade, Lauren Peter, Mathai Mammen, Ramya Nityanandam, Renita Brown, Frank Wegmann, Bing Chen, Jingyou Yu, Aaron G. Schmidt, Mehtap Cabus, Katherine McMahan, Shant H. Mahrokhian, John D. Ventura, Makda S. Gebre, Noe B. Mercado, Lucy Rutten, Roland Zahn, Jared Feldman, Alex Van Ry, Catherine Jacob-Dolan, Ralph S. Baric, Jinyan Liu, Esther A. Bondzie, Amanda Strasbaugh, Laurent Pessaint, Timothy M. Caradonna, Stephanie Fischinger, Elyse Teow, R. Keith Reeves, Douglas A. Lauffenburger, Mark J. G. Bakkers, Danielle van Manen, Mark G. Lewis, Kaylee Verrington, Rinke Bos, Huahua Wan, Emily Hoffman, Gabriel Dagotto, Caroline Atyeo, Shivani A. Patel, Ted Kwaks, Galit Alter, Blake M. Hauser, Jort Vellinga, Carolin Loos, Johan Van Hoof, Felix Nampanya, Zhenfeng Li, Dan H. Barouch, David Zuijdgeest, Zijin Lin, Johannes P. M. Langedijk, David R. Martinez, Sietske K. Rosendahl Huber, Yongfei Cai, Paul Stoffels, Xuan He, Serge Zouantchangadou, Abishek Chandrashekar
Publikováno v:
Nature
Autor:
Makda S. Gebre, John S. Burke, Peter K. Sorger, Mark G. Lewis, Gabriel Dagotto, Caroline Atyeo, Roland Zahn, Brad Finneyfrock, Xuan He, Laurent Pessaint, Jacob D. Estes, Galit Alter, Linda M. Wrijil, Aaron G. Schmidt, David R. Martinez, Margaret Terry, Abishek Chandrashekar, Jingyou Yu, Kathleen Busman-Sahay, Michael Nekorchuk, Lisa H. Tostanoski, Anthony Cook, Renita Brown, Catherine Jacob-Dolan, Michelle A. Lifton, Dan H. Barouch, Esther A. Bondzie, Zoltan Maliga, Noe B. Mercado, Frank Wegmann, Hanne Andersen, Zhenfeng Li, Matthew D. Slein, Sarah Ducat, Alex Van Ry, Kelvin Blade, Jack Greenhouse, Peter Abbink, Shant H. Mahrokhian, Lauren Peter, Lori F. Maxfield, Stephanie Fischinger, Ralph S. Baric, Nicole Kordana, Andrew D. Miller, Amanda J. Martinot, Joseph P. Nkolola, Katherine McMahan, Jason Velasco, Elyse Teow, Tammy Taylor, Jinyan Liu, Ramya Nityanandam
Publikováno v:
Science
Science (New York, N.y.)
Science (New York, N.y.)
An understanding of protective immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for vaccine and public health strategies aimed at ending the global coronavirus disease 2019 (COVID-19) pandemic. A key unanswered que