Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gabriel Courchesne"'
Publikováno v:
Tetrahedron: Asymmetry. 15:3587-3590
The stereoselective acetylation of meso-decalindiols 1 and 2 by vinyl acetate in the presence of Candida antarctica lipase gave monoester (1R,4S,4aR,8aS)-5 and (1R,4S,4aR,8aS)-6 in high enantiomeric excess (ee ⩾98%). The hydrolysis of the correspon
Publikováno v:
Tetrahedron: Asymmetry. 14:2567-2571
Dolabriferol is a marine polypropionate characterized by an unusual non-contiguous carbon skeleton. The two polypropionate subunits are linked by an ester function. The acid moiety of dolabriferol (ee=97%) was synthesized in five steps and 58% overal
Autor:
Robert Chênevert, Gabriel Courchesne
Publikováno v:
Tetrahedron: Asymmetry. 6:2093-2096
The stereoselective acetylation of meso-3-( tert -butyldimethylsiloxy)-2,4-dimethyl-1,5-pentanediol by vinyl acetate in the presence of Candida rugosa lipase in organic medium gave the corresponding (2R, 3R, 4S) mono ester in high enantiomeric purity
Publikováno v:
Chemistry Letters. 23:93-96
We report the first asymmetric synthesis of amidinomycin, an antiviral antibiotic metabolite. Amidinomycin of high enantiomeric purity (ee 91%) was prepared from norbornylene in 8 steps. The key step is an enzymatic discrimination of enantiotopic gro
Publikováno v:
ChemInform. 25
We report the first asymmetric synthesis of amidinomycin, an antiviral antibiotic metabolite. Amidinomycin of high enantiomeric purity (ee 91%) was prepared from norbornylene in 8 steps. The key step is an enzymatic discrimination of enantiotopic gro
Autor:
Gabriel Courchesne, Robert Chênevert
Publikováno v:
ChemInform. 27
The stereoselective acetylation of meso-3-( tert -butyldimethylsiloxy)-2,4-dimethyl-1,5-pentanediol by vinyl acetate in the presence of Candida rugosa lipase in organic medium gave the corresponding (2R, 3R, 4S) mono ester in high enantiomeric purity
Autor:
Gabriel Courchesne, Robert Chênevert
Publikováno v:
ChemInform. 28
Acetylation of 2-[4-(benzyloxy)-2-nitrophenyl]propane-1,3-diol with vinyl acetate in the presence of porcine pancreatic lipase gave the (R)-mono-acetate (ee = 92%). The (S)-mono-acetate was obtained via acetylation of the diol followed by transesteri
Autor:
Francois LaFlamme, Michel Couturier, Louis-Philippe Beauregard, Francis Beaulieu, Alexandre L'Heureux, Gabriel Courchesne
Publikováno v:
ChemInform. 41
Aminodifluorosulfinium tetrafluoroborate salts were found to act as efficient deoxofluorinating reagents when promoted by an exogenous fluoride source and, in most cases, exhibited greater selectivity by providing less elimination byproduct as compar
Autor:
Louis-Philippe Beauregard, Francis Beaulieu, Alexandre L'Heureux, Gabriel Courchesne, Michel Couturier, Francois LaFlamme
Publikováno v:
Organic Letters
Aminodifluorosulfinium tetrafluoroborate salts were found to act as efficient deoxofluorinating reagents when promoted by an exogenous fluoride source and, in most cases, exhibited greater selectivity by providing less elimination byproduct as compar
Publikováno v:
Bioorganicmedicinal chemistry. 14(15)
The stereoselective acylation of the achiral chromanedimethanol derivative 1 by vinyl acetate in the presence of Candida antarctica lipase B gave the ( S )-monoester 2 in high enantiomeric purity (ee ⩾ 98%). Enzymatic hydrolysis of diesters of comp