Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gabriel Castro‐Falcón"'
Autor:
Gabriel Castro-Falcón, Kaitlin E. Creamer, Alexander B. Chase, Min Cheol Kim, Douglas Sweeney, Evgenia Glukhov, William Fenical, Paul R. Jensen
Publikováno v:
J Nat Prod
A new manumycin-type natural product named pacificamide (1) and its candidate biosynthetic gene cluster (pac) were discovered from the marine actinobacterium Salinispora pacifica CNT-855. The structure of the compound was determined using NMR, electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480b851e8336e193d1891ba430ca266f
https://doi.org/10.1021/acs.jnatprod.1c01117
https://doi.org/10.1021/acs.jnatprod.1c01117
Autor:
Isabel V. L. Wilkinson, Gabriel Castro‐Falcón, Maria C. Roda‐Serrat, Trevor N. Purdy, Jan Straetener, Melanie M. Brauny, Lisa Maier, Heike Brötz‐Oesterhelt, Lars P. Christensen, Stephan A. Sieber, Chambers C. Hughes
Publikováno v:
ChemBioChem. 24
The blue biliprotein phycocyanin, produced by photoautotrophic cyanobacteria including spirulina (Arthrospira) and marketed as a natural food supplement or "nutraceutical," is reported to have anti-inflammatory, antioxidant, immunomodulatory and anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916926da323402266ebdc6edee4bc452
https://doi.org/10.1002/cbic.202200455
https://doi.org/10.1002/cbic.202200455
Publikováno v:
Applied and environmental microbiology, vol 88, iss 1
The obligate marine actinobacterial genus Salinispora has become a model organism for natural product discovery, yet little is known about the ecological functions of the compounds produced by this taxon. The aims of this study were to assess the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c361fc0c26862d1efa37ad575f6bb1a5
https://doi.org/10.1128/aem.01176-21
https://doi.org/10.1128/aem.01176-21
Autor:
Bernd Schneider, Yoko Nakamura, Katrin Luck, Eric A. Schmelz, Gabriel Castro-Falcón, Christian Paetz, Tobias G. Köllner, Vinzenz Handrick, Alisa Huffaker, Chambers C. Hughes, Sowmya Poosapati, Jonathan Gershenzon, Grit Kunert, Christiane Förster, Yezhang Ding
Publikováno v:
Plant Physiology
Plant physiology, vol 188, iss 1
Plant physiology, vol 188, iss 1
Fungal infection of grasses, including rice (Oryza sativa), sorghum (Sorghum bicolor), and barley (Hordeum vulgare), induces the formation and accumulation of flavonoid phytoalexins. In maize (Zea mays), however, investigators have emphasized benzoxa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4107bd2975b50ed7331ac822db049d65
https://hdl.handle.net/21.11116/0000-0009-6A23-921.11116/0000-0009-6A26-621.11116/0000-0009-D70F-5
https://hdl.handle.net/21.11116/0000-0009-6A23-921.11116/0000-0009-6A26-621.11116/0000-0009-D70F-5
Publikováno v:
Appl Environ Microbiol
The obligate marine actinobacterial genus Salinispora has become a model organism for natural product discovery, yet little is known about the ecological functions of the compounds produced by this taxon. The aims of this study were to assess the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a61b0cd35ac1df158cad656c74783513
https://pubmed.ncbi.nlm.nih.gov/34669450
https://pubmed.ncbi.nlm.nih.gov/34669450
Autor:
Elly Poretsky, Bing Yang, Mengxi Wu, Evan Saldivar, Steven P. Briggs, Yezhang Ding, Alisa Huffaker, Philipp Zerbe, Eric A. Schmelz, Karl A. Kremling, Chambers C. Hughes, Sibongile Mafu, Andrew Sher, Robert J. Schmitz, Si Nian Char, Lexiang Ji, Zhouxin Shen, Shawn A. Christensen, Edward S. Buckler, Katherine M. Murphy, Jörg Bohlmann, Qiang Wang, Gabriel Castro-Falcón
Publikováno v:
Nature Plants. 5:1043-1056
Duplication and divergence of primary pathway genes underlie the evolution of plant specialized metabolism; however, mechanisms partitioning parallel hormone and defence pathways are often speculative. For example, the primary pathway intermediate en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31579e5daf0e2f2a33e06aa839fc877c
https://doi.org/10.1038/s41477-019-0509-6
https://doi.org/10.1038/s41477-019-0509-6
Autor:
Nathan A. Moss, Grant Seiler, Tiago F. Leão, Gabriel Castro‐Falcón, Lena Gerwick, Chambers C. Hughes, William H. Gerwick
Publikováno v:
Angewandte Chemie. 131:9125-9129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efec8c56f987337371c188d7b27075b8
https://doi.org/10.1002/ange.201902571
https://doi.org/10.1002/ange.201902571
Autor:
Seth J. Field, Anne-Catrin Letzel, David J. Hamelin, Chambers C. Hughes, Manoj K. Rathinaswamy, Grant S. Seiler, John E. Burke, Stefanie L. Makowski, Gabriel Castro-Falcón, Rommie E. Amaro, Reece M. Hoffmann, Özlem Demir
Publikováno v:
Journal of medicinal chemistry, vol 61, iss 23
Using a novel chemistry-based assay for identifying electrophilic natural products from unprocessed extracts, we identified the PI3-kinase/mTOR dual inhibitor neolymphostin A from Salinispora arenicola CNY-486. The method further showed that the viny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fbb23443cf7aa4b02fd6a08822bb84
https://doi.org/10.1021/acs.jmedchem.8b00975
https://doi.org/10.1021/acs.jmedchem.8b00975
Autor:
Eric A. Schmelz, J. Bennett Addison, Gabriel Castro-Falcón, Qiang Wang, Alisa Huffaker, Omar Yaacoobi, Yezhang Ding, Jörg Bohlmann, Zhouxin Shen, Katherine M. Murphy, Mariam Betsiashvili, Sibongile Mafu, Chambers C. Hughes, Steven P. Briggs, Philipp Zerbe
Publikováno v:
Plant Physiology. 176:2677-2690
Terpenoids are a major component of maize (Zea mays) chemical defenses that mediate responses to herbivores, pathogens, and other environmental challenges. Here, we describe the biosynthesis and elicited production of a class of maize diterpenoids, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d6e24353d5fe7ba0e8d0f41fb92f688
https://doi.org/10.1104/pp.17.01351
https://doi.org/10.1104/pp.17.01351
Autor:
Chambers C. Hughes, Nathan A. Moss, Lena Gerwick, William H. Gerwick, Grant S. Seiler, Tiago Leao, Gabriel Castro-Falcón
Publikováno v:
Angew Chem Int Ed Engl
Hybrid type I PKS/NRPS biosynthetic pathways typically proceed in a collinear manner wherein one molecular building block is enzymatically incorporated in a sequence that corresponds to gene arrangement. In this work, genome mining combined with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2ace413fab75211b169f52a339d4df
https://pubmed.ncbi.nlm.nih.gov/31071229
https://pubmed.ncbi.nlm.nih.gov/31071229