Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gabriel C. Graffius"'
Autor:
Shane T. Grosser, Angela Spartalis, John Higgins, George Zhou, Gabriel C. Graffius, Cindy Starbuck, Busolo Wabuyele, Aaron Moment, Paul Fernandez, Lei Sun, Ganeshwar Prasad
Publikováno v:
Organic Process Research & Development. 20:653-660
The transamination-chemistry-based process for sitagliptin is a through-process, which challenges the crystallization of the active pharmaceutical ingredient (API) in a batch stream composed of multiple components. Risk-assessment-based design of exp
Autor:
Xiaoyi Gong, Christopher J. Welch, Erik L. Regalado, Xiaodong Bu, Gabriel C. Graffius, Yong Liu, Naijun Wu, Timothy Nowak
Publikováno v:
Green Chemistry. 18:3732-3739
Gas Chromatography-Flame Ionization Detection (GC-FID) analysis for quantitation of residual solvents in drugs and synthetic intermediates is one of the most important and frequently used tests in the pharmaceutical industry. However, as currently pr
Autor:
Gabriel C. Graffius, Daniel Zewge, Holst M. Halsey, Robert Hartman, Brandon M. Jocher, Xiaodong Bu, Erik L. Regalado, Gary Lee, Frank Bernardoni
Publikováno v:
Journal of chromatography. A. 1518
Volatile amines are among the most frequently used chemicals in organic and pharmaceutical chemistry. Synthetic route optimization often involves the evaluation of several different amines requiring the development and validation of analytical method
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 30(49)
Methyl-terminated poly(dimethylsiloxanes) (PDMSs) are typically considered to be inert and not suitable for surface functionalization reactions because of the absence of readily hydrolyzable groups. Nevertheless, these siloxanes do react with silica