Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gabriel Boyle"'
Autor:
Katherine A. Sitko, Lai Hong Wong, Allan E. Rettie, Gabriel Boyle, Clara J. Amorosi, John P. Kowalski, Melissa A Chiasson, Douglas M. Fowler, Maitreya J. Dunham, Matthew G. McDonald
Publikováno v:
Am J Hum Genet
CYP2C9 encodes a cytochrome P450 enzyme responsible for metabolizing up to 15% of small molecule drugs, and CYP2C9 variants can alter the safety and efficacy of these therapeutics. In particular, the anti-coagulant warfarin is prescribed to over 15 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246f02008e4beb6e3257ac1171b8faf7
https://doi.org/10.1016/j.ajhg.2021.07.001
https://doi.org/10.1016/j.ajhg.2021.07.001
Autor:
Gabriel Boyle, Jacqeline Aldaco, Michael LaCroix, Fatou Amar, Mathew A. Sherman, George S. Bloom, Jennifer L. Brown, Shahzad S. Khan, Sylvain Lesné, Michael K. Lee
Publikováno v:
Acta neuropathologica. 136(4)
α-Synuclein (αSyn) histopathology defines several neurodegenerative disorders, including Parkinson's disease, Lewy body dementia, and Alzheimer's disease (AD). However, the functional link between soluble αSyn and disease etiology remains elusive,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8aac004b5ff4ecf711e81bf88a0cf4
https://pubmed.ncbi.nlm.nih.gov/29995210
https://pubmed.ncbi.nlm.nih.gov/29995210
Autor:
Sylvain Lesné, Gabriel Boyle, Alain Buisson, Megan Larson, Liu Chang, Fatou Amar, Mathew A. Sherman, Jürgen Götz, Travis Rush
Publikováno v:
Science signaling. 10(478)
Oligomeric forms of amyloid-forming proteins are believed to be the principal initiating bioactive species in many neurodegenerative disorders, including Alzheimer’s disease (AD). Amyloid-β (Aβ) oligomers are implicated in AD-associated phosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3ef1f76cfa6d9083176b3e88f80969
https://pubmed.ncbi.nlm.nih.gov/35727863
https://pubmed.ncbi.nlm.nih.gov/35727863
Autor:
Michael LaCroix, Mathew A. Sherman, Fabio Benfenati, Gabriel Boyle, Julie A. Schneider, Hallie Schley, David A. Bennett, Camille Miel, Megan Larson, Rakez Kayed, Susan Greimel, Sylvain Lesné, Michael K. Lee, Fatou Amar
Mounting evidence indicates that soluble oligomeric forms of amyloid proteins linked to neurodegenerative disorders, such as amyloid-β (Aβ), tau, or α-synuclein (αSyn) might be the major deleterious species for neuronal function in these diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a9506d2fb3e59c460fefdee5db0e86
http://hdl.handle.net/11567/889617
http://hdl.handle.net/11567/889617
