Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer's disease in a multigenerational Colombian Family.

Autor: Johanna Alexandra Tejada Moreno, Andrés Villegas Lanau, Lucia Madrigal Zapata, Ana Yulied Baena Pineda, Juan Velez Hernandez, Omer Campo Nieto, Alejandro Soto Ospina, Pedronel Araque Marín, Lavanya Rishishwar, Emily T Norris, Aroon T Chande, I King Jordan, Gabriel Bedoya Berrio

Publikováno v: PLoS ONE, Vol 17, Iss 7, p e0269955 (2022)

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, affecting over 50 million people worldwide in 2020 and this number will triple to 152 million by 2050. Much of the increase will be in developing countries like Colombia. I

Externí odkaz: https://doaj.org/article/cc8ace5abf474e2ab4ecdcc55eca3490

Calidad de Vida Relacionada con la Salud en Un Grupo de Adolescentes de Medellín (Colombia): Asociación con Aspectos Sociodemográficos, Exceso de Peso u Obesidad y Actividad Física

Autor: EDWARDS JOANY OSSA GONZÁLEZ, ELKIN FERNANDO ARANGO VÉLEZ, CLAUDIA MARÍA VELÁSQUEZ RODRÍGUEZ, ANGÉLICA MARÍA MUÑOZ CONTRERAS, ALEJANDRO ESTRADA RESTREPO, GABRIEL BEDOYA BERRíO, FREDY ALONSO PATIÑO VILLADA, GLORIA MARÍA AGUDELO OCHOA

Publikováno v: Revista Colombiana de Psicología, Vol 23, Iss 2, Pp 255-267 (2014)

El objetivo del estudio fue describir la calidad de vida relacionada con la salud ( C v RS ) y su asociación con aspectos sociodemográficos, el exceso de peso u obesidad y la actividad física ( a F ) en un grupo de adolescentes de la ciudad de Med

Externí odkaz: https://doaj.org/article/3e9d0805b912414eb8617cb29f4f9905

Association of the TPO gene in Colombian families with type 1 diabetes Asociación del gen TPO en familias colombianas con la diabetes tipo 1

Autor: Federico Uribe Londoño, Andrés Ruiz Linares, Gabriel Bedoya Berrío, Vital Balthazar González, Javier Gutiérrez Achurry, Nicolas Pineda Trujillo, Juan Manuel Alfaro

Publikováno v: Iatreia, Vol 22, Iss 4, Pp 323-329 (2009)

We have found linkage and association of type 1 diabetes (T1D) to 2p25. The TPO gene lies within this region. Our aim was to test the association of this gene with the susceptibility to T1D in a group of Colombian families, all of them originated in

Externí odkaz: https://doaj.org/article/c90b541ec0f34fe299dc6acfdeb1cc79

Genetic linkage analysis of type 1 diabetes mellitus to markers on chromosomes 2 and 11 in families from Antioquia, Colombia Análisis de ligamiento genético de la diabetes mellitus tipo 1, a marcadores de los cromosomas 2 y 11 en familias antioqueñas

Autor: Gabriel Bedoya Berrío, Constanza Duque, Iván Duque, Beatriz Valencia, Débora Castrillón, Andrés Pérez, Javier Cerón, Alberto Villegas, Guillermo Latorre Sierra, Fabiola Montoya, Nicolás Pineda Trujillo, Federico Uribe, Andrés Ruiz

Publikováno v: Iatreia, Vol 17, Iss 2, Pp 93-104 (2004)

DIABETES MELLITUS (DM) comprises e heterogeneous group of hypoglycemic disorders, that are grouped according to their physiopathology and etiology; the most notorious ones are type 1 DM (DM1) and type 2 DM (DM2); DM1 is characterized by early onset a

Externí odkaz: https://doaj.org/article/98747121d1984ddfa3a8e1ff526f6c97

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture.

Autor: Lea K Davis, Dongmei Yu, Clare L Keenan, Eric R Gamazon, Anuar I Konkashbaev, Eske M Derks, Benjamin M Neale, Jian Yang, S Hong Lee, Patrick Evans, Cathy L Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrio, Oscar J Bienvenu, Michael H Bloch, Rianne M Blom, Ruth D Bruun, Cathy L Budman, Beatriz Camarena, Desmond Campbell, Carolina Cappi, Julio C Cardona Silgado, Danielle C Cath, Maria C Cavallini, Denise A Chavira, Sylvain Chouinard, David V Conti, Edwin H Cook, Vladimir Coric, Bernadette A Cullen, Dieter Deforce, Richard Delorme, Yves Dion, Christopher K Edlund, Karin Egberts, Peter Falkai, Thomas V Fernandez, Patience J Gallagher, Helena Garrido, Daniel Geller, Simon L Girard, Hans J Grabe, Marco A Grados, Benjamin D Greenberg, Varda Gross-Tsur, Stephen Haddad, Gary A Heiman, Sian M J Hemmings, Ana G Hounie, Cornelia Illmann, Joseph Jankovic, Michael A Jenike, James L Kennedy, Robert A King, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L Lowe, Fabio Macciardi, James T McCracken, Lauren M McGrath, Sandra C Mesa Restrepo, Rainald Moessner, Jubel Morgan, Heike Muller, Dennis L Murphy, Allan L Naarden, William Cornejo Ochoa, Roel A Ophoff, Lisa Osiecki, Andrew J Pakstis, Michele T Pato, Carlos N Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L Rauch, Tobias J Renner, Victor I Reus, Margaret A Richter, Mark A Riddle, Mary M Robertson, Roxana Romero, Maria C Rosàrio, David Rosenberg, Guy A Rouleau, Stephan Ruhrmann, Andres Ruiz-Linares, Aline S Sampaio, Jack Samuels, Paul Sandor, Brooke Sheppard, Harvey S Singer, Jan H Smit, Dan J Stein, E Strengman, Jay A Tischfield, Ana V Valencia Duarte, Homero Vallada, Filip Van Nieuwerburgh, Jeremy Veenstra-Vanderweele, Susanne Walitza, Ying Wang, Jens R Wendland, Herman G M Westenberg, Yin Yao Shugart, Euripedes C Miguel, William McMahon, Michael Wagner, Humberto Nicolini, Danielle Posthuma, Gregory L Hanna, Peter Heutink, Damiaan Denys, Paul D Arnold, Ben A Oostra, Gerald Nestadt, Nelson B Freimer, David L Pauls, Naomi R Wray, S Evelyn Stewart, Carol A Mathews, James A Knowles, Nancy J Cox, Jeremiah M Scharf

Publikováno v: PLoS Genetics, Vol 9, Iss 10, p e1003864 (2013)

The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated variants. We have quanti

Externí odkaz: https://doaj.org/article/dcefb124869a49fdb60299acf97e56f6