Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Gabriel Baverel"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 11, Pp 1497-1510 (2022)
Abstract Extending the potential of precision dosing requires evaluating methodologies offering more flexibility and higher degree of personalization. Reinforcement learning (RL) holds promise in its ability to integrate multidimensional data in an a
Externí odkaz:
https://doaj.org/article/0232ad52d47f4c1d90e4ef7fcbd7e2bf
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971701
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9144fea12add6620e5f12fdec0b1a5d
https://doi.org/10.1007/978-1-4939-7172-5_14
https://doi.org/10.1007/978-1-4939-7172-5_14
Publikováno v:
Neuroscience. 248:243-251
To examine the effect of glucose on the cerebral metabolism of glutamine, rat brain slices were incubated with 5 mM [3- 13 C]glutamine without and with 5 mM unlabeled glucose. Tissue plus medium extracts were analyzed by using enzymatic and 13 C NMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d810227a98ddc4eaf7344b3374c5187
https://doi.org/10.1016/j.neuroscience.2013.05.064
https://doi.org/10.1016/j.neuroscience.2013.05.064
Autor:
Agnès Duplany, Burhan Knouzy, Bernard Ferrier, Guy Martin, Maha El Hage, Catherine Gauthier, Gabriel Baverel
Publikováno v:
Xenobiotica. 43:54-62
1.Unlike cell lines and primary cells in culture, precision-cut tissue slices remain metabolically differentiated for at least 24-48 h and allow to study the effect of xenobiotics during short-term and long-term incubations. 2.In this article, we ill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa5e34dddfae42573bb5444c7cc6bdb
https://doi.org/10.3109/00498254.2012.725142
https://doi.org/10.3109/00498254.2012.725142
Publikováno v:
Epilepsy Research. 99:94-100
Summary Sodium valproate is a drug widely used for the treatment of epilepsy and mood disorders. We studied the effect of valproate on cerebral energy metabolism by incubating rat brain slices with 5mM [3- 13 C]glutamate in the absence and the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6ee02c4cfb760fc6e1cfd14da1a5d2
https://doi.org/10.1016/j.eplepsyres.2011.10.028
https://doi.org/10.1016/j.eplepsyres.2011.10.028
Publikováno v:
Neurochemistry International. 59:1145-1154
Since glucose is the main cerebral substrate, we have characterized the metabolism of various 13C glucose isotopomers in rat brain slices. For this, we have used our cellular metabolomic approach that combines enzymatic and carbon 13 NMR techniques w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de9a95f53c2b24010d586ebee85625a
https://doi.org/10.1016/j.neuint.2011.10.009
https://doi.org/10.1016/j.neuint.2011.10.009
Publikováno v:
Neurochemistry International. 58:896-903
This study was performed to analyze the metabolic fate of a high concentration (5 mM) of glutamine and glutamate in rat brain slices and the participation of these amino acids in the glutamine–glutamate cycle. For this, brain slices were incubated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed0a68df75dc026bab22bd7d7189378
https://doi.org/10.1016/j.neuint.2011.02.018
https://doi.org/10.1016/j.neuint.2011.02.018
Publikováno v:
Toxicology in Vitro. 24:99-107
Chloroacetaldehyde, one of the main products of hepatic ifosfamide metabolism, contributes to its nephrotoxicity. However, the pathophysiology of this toxicity is not fully understood. The present work examined the time and dose effects of clinically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a9a578d966a5de3d6c4045efa90f645
https://doi.org/10.1016/j.tiv.2009.08.026
https://doi.org/10.1016/j.tiv.2009.08.026
Autor:
Sophie Renault, Guy Martin, Agnès Conjard-Duplany, Hassan Faiz, Rudy Gadet, Gabriel Baverel, Bernard Ferrier
Publikováno v:
Toxicology and Applied Pharmacology. 242:9-17
As part of a study on uranium nephrotoxicity, we investigated the effect of uranyl nitrate in isolated human and mouse kidney cortex tubules metabolizing the physiological substrate lactate. In the millimolar range, uranyl nitrate reduced lactate rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e7bbecbbfdbdc7c09e93d5ce9d1075
https://doi.org/10.1016/j.taap.2009.09.002
https://doi.org/10.1016/j.taap.2009.09.002
Publikováno v:
International Journal of Hematology. 88:362-368
The aim of this study was to investigate an indirect method based on a determination of absolute norms of variation in biological markers that could be used to identify autologous blood transfusion within the framework of the fight against doping. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6897668c1295cead0998b516ce6b6800
https://doi.org/10.1007/s12185-008-0182-4
https://doi.org/10.1007/s12185-008-0182-4