Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Gabriel Alvares Borges"'
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Curcumin downregulates the PI3K–AKT–mTOR pathway and inhibits growth and progression in head and neck cancer cells
Autor: Silvia Taveira Elias, Ricardo D. Coletta, Gabriel Alvares Borges, Bruna Rabelo Amorim, Caroline Lourenço de Lima, Eliete Neves Silva Guerra, Rogerio M. Castilho, Cristiane H. Squarize
Publikováno v: Phytotherapy Research. 34:3311-3324
Curcumin, a polyphenol isolated from the rhizome of Curcuma longa, has been studied because of its antioxidant, antimicrobial, and antiinflammatory properties. This study aimed to evaluate the effects of curcumin on head and neck cancer (HNC) cell li
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfddaba4307ae16f554b03cce7cc5b8
https://doi.org/10.1002/ptr.6780
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Abstract B023: Enhanced survival and adherence of melphalan-induced senescent-like dormant multiple myeloma cells co-cultured with bone marrow stromal cells
Autor: Angelo J. Guilatco, Gabriel Alvares Borges, Tamar Tchkonia, James L. Kirkland, Taxiarchis Kourelis, Matthew T. Drake, Megan Weivoda
Publikováno v: Cancer Research. 83:B023-B023
Multiple myeloma (MM) is an incurable plasma cell cancer. Therapeutic advances have greatly improved patient survival; however, all patients are expected to relapse. New treatments are critically needed to overcome relapse and provide durable respons
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e519a0f09c8b2b06846a2ee78a6d90dc
https://doi.org/10.1158/1538-7445.agca22-b023
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Abstract B020: Pre-malignant plasma cells exhibit a senescence-like phenotype and accumulation of transposable elements
Autor: Gabriel Alvares Borges, Angelo Jose Guilatco, Christine M. Hachfeld, Ming Ruan, Sonya Royzenblat, Ming Xu, Claire M. Edwards, Marta Diaz-delCastillo, Thomas L. Andersen, Taxiarchis Kourelis, Tamar Tchkonia, James L. Kirkland, Matthew T. Drake, Megan Weivoda
Publikováno v: Cancer Research. 83:B020-B020
This abstract is being presented as a short talk in the scientific program. A full abstract is available in the Short Talks from Proffered Abstracts section (PR012) of the Conference Proceedings. Citation Format: Gabriel Alvares Borges, Angelo Jose G
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d180acc8b6ab4ebd151fdf3525f8a275
https://doi.org/10.1158/1538-7445.agca22-b020
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6
Abstract PR012: Pre-malignant plasma cells exhibit a senescence-like phenotype and accumulation of transposable elements
Autor: Gabriel Alvares Borges, Angelo Jose Guilatco, Christine M. Hachfeld, Ming Ruan, Sonya Royzenblat, Ming Xu, Claire M. Edwards, Marta Diaz-delCastillo, Thomas L. Andersen, Taxiarchis Kourelis, Tamar Tchkonia, James L. Kirkland, Matthew T. Drake, Megan Weivoda
Publikováno v: Cancer Research. 83:PR012-PR012
Multiple myeloma (MM) is a clonal plasma cell (PC) cancer that is preceded by the benign conditions monoclonal gammopathy of undetermined significance (MGUS) and smoldering MM (SMM). While MGUS/SMM PCs are not proliferative, many of the oncogenes and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1d898b30c09a89e32e37e7bb6fd7976
https://doi.org/10.1158/1538-7445.agca22-pr012
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8
Pharmacological PTEN inhibition: potential clinical applications and effects in tissue regeneration
Autor: Cristiane H. Squarize, Rogerio M. Castilho, Eliete Ns Guerra, Liana Preto Webber, Gabriel Alvares Borges, Ana Elizia Mascarenhas Marques
Publikováno v: Regen Med
Although the human body can heal, it takes time, and slow healing and chronic wounds often occur. Thus, identifying novel therapies to aid regeneration is needed. Here, we conducted a systematic review following the Preferred Reporting Items for Syst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00ecc306bf4834151763672228fcf60
https://europepmc.org/articles/PMC7202261/
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In vitro evaluation of wound healing and antimicrobial potential of ozone therapy
Autor: Sandra Márcia Mazutti da Silva, Sérgio Bruzadelli Macedo, Pérola Oliveira Magalhães, Eliete Neves Silva Guerra, Silvia Taveira Elias, Gabriel Alvares Borges, Ana Paula Dias Ribeiro
Publikováno v: Journal of Cranio-Maxillofacial Surgery. 45:364-370
Although ozone therapy is extensively applied when wound repair and antimicrobial effect are necessary, little is known about cellular mechanisms regarding this process. Thus, this study aimed to evaluate ozone cytotoxicity in fibroblasts (L929) and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c20f78963c44884ee58f31ebda748a9
https://doi.org/10.1016/j.jcms.2017.01.005
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Asparaginase induces selective dose- and time-dependent cytotoxicity, apoptosis, and reduction of NFκB expression in oral cancer cells
Autor: Tassiana Souza De Araujo, Rogerio M. Castilho, Carlos H. V. Nascimento-Filho, Paula Monteiro Souza, Cristiane H. Squarize, Gabriel Alvares Borges, Silvia Taveira Elias, Pérola Oliveira Magalhães, Eliete Neves Silva Guerra
Publikováno v: Clinical and experimental pharmacologyphysiologyREFERENCES. 47(5)
Asparaginase is fundamental to the treatment of haematological malignancies. However, little has been studied on the effects that asparaginase could exert on solid tumours. Thus, this study aimed to evaluate the effects of asparaginase on an oral car
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f3519c27348d0afec551496f0b887d
https://pubmed.ncbi.nlm.nih.gov/31943292
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