Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Gabriel A. Al-Ghalith"'
Autor:
Dimitrios N. Sidiropoulos, Gabriel A. Al-Ghalith, Robin R. Shields-Cutler, Tonya L. Ward, Abigail J. Johnson, Pajau Vangay, Dan Knights, Purna C. Kashyap, Yibo Xian, Amanda E. Ramer-Tait, Jonathan B. Clayton
Publikováno v:
Animal Microbiome, Vol 2, Iss 1, Pp 1-11 (2020)
Abstract Background The gut microbiome harbors trillions of bacteria that play a major role in dietary nutrient extraction and host metabolism. Metabolic diseases such as obesity and diabetes are associated with shifts in microbiome composition and h
Externí odkaz:
https://doaj.org/article/ac4915b761424c8ab9f91ae050147814
Autor:
Qiyun Zhu, Uyen Mai, Wayne Pfeiffer, Stefan Janssen, Francesco Asnicar, Jon G. Sanders, Pedro Belda-Ferre, Gabriel A. Al-Ghalith, Evguenia Kopylova, Daniel McDonald, Tomasz Kosciolek, John B. Yin, Shi Huang, Nimaichand Salam, Jian-Yu Jiao, Zijun Wu, Zhenjiang Z. Xu, Kalen Cantrell, Yimeng Yang, Erfan Sayyari, Maryam Rabiee, James T. Morton, Sheila Podell, Dan Knights, Wen-Jun Li, Curtis Huttenhower, Nicola Segata, Larry Smarr, Siavash Mirarab, Rob Knight
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The authors build a reference phylogeny of 10,575 evenly-sampled bacterial and archaeal genomes, based on 381 markers. The results indicate a remarkably closer evolutionary proximity between Archaea and Bacteria than previous estimates that used fewe
Externí odkaz:
https://doaj.org/article/963471f628f44741a9d932ae0fd75f6b
Autor:
Joao Carlos Gomes-Neto, Natasha Pavlovikj, Carmen Cano, Baha Abdalhamid, Gabriel Asad Al-Ghalith, John Dustin Loy, Dan Knights, Peter C. Iwen, Byron D. Chaves, Andrew K. Benson
Publikováno v:
Frontiers in Sustainable Food Systems, Vol 5 (2021)
The recent incorporation of bacterial whole-genome sequencing (WGS) into Public Health laboratories has enhanced foodborne outbreak detection and source attribution. As a result, large volumes of publicly available datasets can be used to study the b
Externí odkaz:
https://doaj.org/article/f618a4b46c5443ecbd753951d0908309
Autor:
Emmanuel Montassier, Gabriel A. Al-Ghalith, Camille Mathé, Quentin Le Bastard, Venceslas Douillard, Abel Garnier, Rémi Guimon, Bastien Raimondeau, Yann Touchefeu, Emilie Duchalais, Nicolas Vince, Sophie Limou, Pierre-Antoine Gourraud, David A. Laplaud, Arnaud B. Nicot, Jean-Paul Soulillou, Laureline Berthelot
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Because of a loss-of-function mutation in the GGTA1 gene, humans are unable to synthetize α1,3-Galactose (Gal) decorated glycans and develop high levels of circulating anti-α1,3-Galactose antibodies (anti-Gal Abs). Anti-Gal Abs have been identified
Externí odkaz:
https://doaj.org/article/be86596bdcbd4dbfb32b4645206d631f
Autor:
Emmanuel Montassier, Gabriel A. Al-Ghalith, Benjamin Hillmann, Kimberly Viskocil, Amanda J. Kabage, Christopher E. McKinlay, Michael J. Sadowsky, Alexander Khoruts, Dan Knights
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Background Dysbiosis of the human gut microbiome is defined as a maladaptive or clinically relevant deviation of the community profile from the healthy or normal state. Dysbiosis has been implicated in an extensive set of metabolic, auto-imm
Externí odkaz:
https://doaj.org/article/9a839aee3d4e4d5995e4d2c9ae318b6c
Autor:
Benjamin Hillmann, Gabriel A. Al-Ghalith, Robin R. Shields-Cutler, Qiyun Zhu, Daryl M. Gohl, Kenneth B. Beckman, Rob Knight, Dan Knights
Publikováno v:
mSystems, Vol 3, Iss 6 (2018)
ABSTRACT Although microbial communities are associated with human, environmental, plant, and animal health, there exists no cost-effective method for precisely characterizing species and genes in such communities. While deep whole-metagenome shotgun
Externí odkaz:
https://doaj.org/article/9d6d318138994f39842dff1305e1ba5a
Autor:
Braden T. Tierney, Pieter Van den Abbeele, Gabriel A. Al-Ghalith, Lynn Verstrepen, Jonas Ghyselinck, Marta Calatayud, Massimo Marzorati, Azza A. Gadir, Brendan Daisley, Gregor Reid, Peter A. Bron, Dirk Gevers, Raja Dhir, Sheri L. Simmons
Publikováno v:
Applied and Environmental Microbiology. 89
The human gut microbiome is sensitive to disruptions by common stressors such as alcohol consumption and antibiotic treatment. In this study, we used an in vitro system modeling the gut microbiome to investigate whether treatment with a microbial syn
Autor:
Braden T. Tierney, James Versalovic, Alessio Fasano, Joseph F. Petrosino, Bruno P. Chumpitazi, Emeran A. Mayer, Jared Boetes, Gerard Smits, Shanthi G. Parkar, Noah Voreades, Ece Kartal, Gabriel A. Al-Ghalith, Marco Pane, Peter A. Bron, Gregor Reid, Raja Dhir, Christopher E. Mason
Publikováno v:
Pediatric Research.
Background Oral microbial therapy has been studied as an intervention for a range of gastrointestinal disorders. Though research suggests that microbial exposure may affect the gastrointestinal system, motility, and host immunity in a pediatric popul
Autor:
Qian Zhang, Gabriel A. Al-Ghalith, Mayumi Kobayashi, Takahiro Segawa, Mitsuto Maeda, Satoshi Okabe, Dan Knights, Satoshi Ishii
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Current approach to identify sources of human pathogens is largely dependent on the cultivation and isolation of target bacteria. For rapid pathogen source identification, culture-independent strain typing method is necessary. In this study, we desig
Externí odkaz:
https://doaj.org/article/95c2db9b8a99439491c85567284d342d
Autor:
Xue-Song Zhang, Jackie Li, Kimberly A Krautkramer, Michelle Badri, Thomas Battaglia, Timothy C Borbet, Hyunwook Koh, Sandy Ng, Rachel A Sibley, Yuanyuan Li, Wimal Pathmasiri, Shawn Jindal, Robin R Shields-Cutler, Ben Hillmann, Gabriel A Al-Ghalith, Victoria E Ruiz, Alexandra Livanos, Angélique B van ‘t Wout, Nabeetha Nagalingam, Arlin B Rogers, Susan Jenkins Sumner, Dan Knights, John M Denu, Huilin Li, Kelly V Ruggles, Richard Bonneau, R Anthony Williamson, Marcus Rauch, Martin J Blaser
Publikováno v:
eLife, Vol 7 (2018)
The early-life intestinal microbiota plays a key role in shaping host immune system development. We found that a single early-life antibiotic course (1PAT) accelerated type 1 diabetes (T1D) development in male NOD mice. The single course had deep and
Externí odkaz:
https://doaj.org/article/5f77e81cd4e5448cbc2595e81c061fe1