Výsledky vyhledávání - "Gabriel A Salg"

Akademický článek

Toward 3D-bioprinting of an endocrine pancreas: A building-block concept for bioartificial insulin-secreting tissue

Autor: Gabriel A Salg, Eric Poisel, Matthias Neulinger-Munoz, Jamina Gerhardus, Daniel Cebulla, Catrin Bludszuweit-Philipp, Vitor Vieira, Felix Nickel, Ingrid Herr, Andreas Blaeser, Nathalia A Giese, Thilo Hackert, Hannes G Kenngott

Publikováno v: Journal of Tissue Engineering, Vol 13 (2022)

Three-dimensional bioprinting of an endocrine pancreas is a promising future curative treatment for patients with insulin secretion deficiency. In this study, we present an end-to-end concept from the molecular to the macroscopic level. Building-bloc

Externí odkaz: https://doaj.org/article/586238002f114a4689c233790fa2608e

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Akademický článek

Multiscale and multimodal imaging for three-dimensional vascular and histomorphological organ structure analysis of the pancreas

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract Exocrine and endocrine pancreas are interconnected anatomically and functionally, with vasculature facilitating bidirectional communication. Our understanding of this network remains limited, largely due to two-dimensional histology and miss

Externí odkaz: https://doaj.org/article/f94bebf717e148d6874bc9a48c628fd6

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Akademický článek

The emerging field of pancreatic tissue engineering: A systematic review and evidence map of scaffold materials and scaffolding techniques for insulin-secreting cells

Autor: Gabriel Alexander Salg, Nathalia A Giese, Miriam Schenk, Felix J Hüttner, Klaus Felix, Pascal Probst, Markus K Diener, Thilo Hackert, Hannes Götz Kenngott

Publikováno v: Journal of Tissue Engineering, Vol 10 (2019)

A bioartificial endocrine pancreas is proposed as a future alternative to current treatment options. Patients with insulin-secretion deficiency might benefit. This is the first systematic review that provides an overview of scaffold materials and tec

Externí odkaz: https://doaj.org/article/7732899a6c4f4ffc87e2eb2dd58a1397

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Vascularization in Bioartificial Parenchymal Tissue: Bioink and Bioprinting Strategies

Autor: Gabriel Alexander Salg, Andreas Blaeser, Jamina Sofie Gerhardus, Thilo Hackert, Hannes Goetz Kenngott

Among advanced therapy medicinal products, tissue-engineered products have the potential to address the current critical shortage of donor organs and provide future alternative options in organ replacement therapy. The clinically available tissue-eng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3fc3a4336c961c2eb588fe92f92fb0

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Human Retrotransposons and the Global Shutdown of Homeostatic Innate Immunity by Oncolytic Parvovirus H-1PV in Pancreatic Cancer

Autor: Nathalia A. Giese, Barbara Leuchs, Matthias Neulinger-Muñoz, Svetlana P Grekova, Michael Volkmar, Dominik Schaack, Anette Heller, Andrea S. Bauer, Elisa Espinet, Jürg P. F. Nüesch, Gabriel Alexander Salg, Thomas Giese, Miriam Schenk

Publikováno v: Viruses
Volume 13
Issue 6
Viruses, Vol 13, Iss 1019, p 1019 (2021)

Although the oncolytic parvovirus H-1PV has entered clinical trials, predicting therapeutic success remains challenging. We investigated whether the antiviral state in tumor cells determines the parvoviral oncolytic efficacy. The interferon/interfero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c7a28b3ac50bf880c8eb8767439978

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Towards 3D-Bioprinting of an Endocrine Pancreas: A Building-Block Concept for Bioartificial Insulin-Secreting Tissue

Autor: Nathalia A. Giese, Gabriel Alexander Salg, Felix Nickel, Munoz Mn, Thilo Hackert, Cebulla D, Ingrid Herr, Poisel E, Goetz Kenngott H, Bludszuweit-Philipp C, Vieira

Background & Aims3D-Bioprinting of an endocrine pancreas is a promising future curative treatment for selected patients with insulin secretion deficiency. In this study we present an end-to-end integrative, scalable concept extending from the molecul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91c99ee8caf2b9d78bd0f2ab1fc7bdfb
https://doi.org/10.1101/2021.02.27.433164

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A reporting and analysis framework for structured evaluation of COVID-19 clinical and imaging data

Publikováno v: npj Digital Medicine, 4 (1), 69
npj Digital Medicine, Vol 4, Iss 1, Pp 1-9 (2021)
NPJ Digital Medicine

The COVID-19 pandemic has worldwide individual and socioeconomic consequences. Chest computed tomography has been found to support diagnostics and disease monitoring. A standardized approach to generate, collect, analyze, and share clinical and imagi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ceac1dd301a53e8bbd1d5f525e4a8d6

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Akademický článek

Spectral organ fingerprints for machine learning-based intraoperative tissue classification with hyperspectral imaging in a porcine model

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Abstract Visual discrimination of tissue during surgery can be challenging since different tissues appear similar to the human eye. Hyperspectral imaging (HSI) removes this limitation by associating each pixel with high-dimensional spectral informati

Externí odkaz: https://doaj.org/article/ebb9fc0545f64ebba5e2b0ae635ad0f5

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