Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gabriel, Braley"'
Autor:
Nancy L. Kuntz, Julie A. Parsons, Russell J. Butterfield, Francy Shu, Sandra P. Reyna, Janbernd Kirschner, Sarah Gheuens, Marco Petrillo, Darryl C. De Vivo, Kathryn J. Swoboda, Christopher Stebbins, Wildon Farwell, Wuh-Liang Hwu, Haluk Topaloglu, Enrico Bertini, Kristina Johnson, Richard Foster, Douglas A. Kerr, Valeria A. Sansone, Monique M. Ryan, Tawfeg Ben-Omran, Stephanie Fradette, Ishir Bhan, Thomas O. Crawford, Richard S. Finkel, Alfred Sandrock, John F. Staropoli, Yuh-Jyh Jong, Gabriel Braley
Publikováno v:
Neuromuscular Disorders
Highlights • NURTURE is an ongoing study of nusinersen started in a presymptomatic stage of SMA. • All infants were ≥25 months old, and alive without permanent ventilation. • All infants achieved independent sitting and 88% (22/25) were walki
Autor:
Alice I. Nichols, Shannon Lubaczewski, Kyle Matschke, Tanya Ramey, Yali Liang, Gabriel Braley
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 52:830-841
Background Potential drugdrug interactions are a concern for patients taking tamoxifen. Objective This study was designed to determine the effect of coadministering desvenlafaxine on tamoxifen pharmacokinetics. Materials and methods This open-label,
Autor:
Deepak Cyril D'Souza, R. Andrew Sewell, Edward Perry, Jacqueline Elander, Michelle Carbuto, Gabriel Braley, Savita G. Bhakta, Mohini Ranganathan, Kim Forselius-Bielen, Brian Pittman, Ashley Williams, Ashley Schnakenberg
Publikováno v:
Psychopharmacology. 219:885-896
Delta-9-tetrahydrocannabinol (THC) is one of the few cannabinoid receptor ligands that can be used to probe the cannabinoid system in humans. Despite increasing interest in the cannabinoid receptor system, use of intravenous THC as a research tool ha
Autor:
Mohini Ranganathan, Savita G. Bhakta, Zoran Zimolo, Deepak Cyril D'Souza, Michael S. Vendetti, Brian Pittman, Gabriel Braley, Edward Perry, Thomas B. Cooper, Stephen Oliver, Rebecca Blaise
Publikováno v:
Psychopharmacology. 198:587-603
Cannabinoids produce a spectrum of effects in humans including euphoria, cognitive impairments, psychotomimetic effects, and perceptual alterations. The extent to which dopaminergic systems contribute to the effects of Delta-9-tetrahydrocannabinol (D
Autor:
Zoran Zimolo, Edward Perry, Ralitza Gueorguieva, John H. Krystal, Thomas B. Cooper, Deepak Cyril D'Souza, Gabriel Braley, Mohini Ranganathan
Publikováno v:
Neuropsychopharmacology. 33:2505-2516
Cannabis is one of the most widely used illicit substances and there is growing interest in the association between cannabis use and psychosis. Delta-9-Tetrahydrocannabinol (Delta-9-THC) the principal active ingredient of cannabis has been shown to i
Autor:
Deepak Cyril D'Souza, Tahir Tellioglu, Zoran Zimolo, Steven Madonick, John H. Krystal, Kimberlee Forselius-Bielen, Edward Perry, Lia Donahue, Roberto Gil, Gabriel Braley, Ralitza Gueorguieva
Publikováno v:
Neuropsychopharmacology. 31:2767-2775
The purpose of this study was to determine whether schizophrenia was associated with alterations in alcohol response that might explain the elevated risk for AUDs in this population. In a randomized, double-blind, placebo-controlled, counter-balanced
Autor:
Deepak Cyril D'Souza, Steven Madonick, Gabriel Braley, Walid M. Abi-Saab, Kimberlee Forselius-Bielen, John H. Krystal, Thomas B. Cooper, Anne Doersch, Ralitza Gueorguieva
Publikováno v:
Biological Psychiatry. 57:594-608
Background Recent advances in the neurobiology of cannabinoids have renewed interest in the association between cannabis and psychotic disorders. Methods In a 3-day, double-blind, randomized, placebo-controlled study, the behavioral, cognitive, motor
Autor:
Gabriel Braley, Shannon Lubaczewski, Yali Liang, Tanya Ramey, Alice I. Nichols, Kyle Matschke
Publikováno v:
Journal of Bioequivalence & Bioavailability.
Study background: The atypical antipsychotic aripiprazole is commonly coadministered with antidepressant drugs as an adjunctive treatment for depression. The goal of the current study was to assess the potential for multiple-dose treatment with the a
Autor:
Jeffrey Paul, Alice I. Nichols, Tanya Ramey, Joel A Posener, Gabriel Braley, Shannon Lubaczewski, Alain Patat, Jessica A Behrle, Kyle Matschke, Yali Liang
Publikováno v:
Journal of Bioequivalence & Bioavailability.
A series of 3 open-label, 2-period, sequential studies were conducted to assess the impact of desvenlafaxine on cytochrome P450 3A4 (CYP3A4) enzyme-mediated metabolism, and the effect of CYP3A4 inhibition on desvenlafaxine metabolism. Study 1 evaluat
Autor:
Michelle, Carbuto, R Andrew, Sewell, Ashley, Williams, Kim, Forselius-Bielen, Gabriel, Braley, Jacqueline, Elander, Brian, Pittman, Ashley, Schnakenberg, Savita, Bhakta, Edward, Perry, Mohini, Ranganathan, Deepak Cyril, D'Souza, Yu-te, Wu
Publikováno v:
Psychopharmacology. 219(3)
Delta-9-tetrahydrocannabinol (THC) is one of the few cannabinoid receptor ligands that can be used to probe the cannabinoid system in humans. Despite increasing interest in the cannabinoid receptor system, use of intravenous THC as a research tool ha