Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Gabri Van Der Pluijm"'
Autor:
Chiara Liverani, Federico La Manna, Arwin Groenewoud, Laura Mercatali, Gabri Van Der Pluijm, Federica Pieri, Davide Cavaliere, Alessandro De Vita, Chiara Spadazzi, Giacomo Miserocchi, Alberto Bongiovanni, Federica Recine, Nada Riva, Dino Amadori, Ennio Tasciotti, Ewa Snaar-Jagalska, Toni Ibrahim
Publikováno v:
Biology Open, Vol 6, Iss 2, Pp 133-140 (2017)
Patient-derived specimens are an invaluable resource to investigate tumor biology. However, in vivo studies on primary cultures are often limited by the small amount of material available, while conventional in vitro systems might alter the features
Externí odkaz:
https://doaj.org/article/b041616b805f44658bdba1de95196424
Autor:
Eugenio Zoni, Gabri van der Pluijm
Publikováno v:
Journal of Bone Oncology, Vol 5, Iss 3, Pp 104-108 (2016)
The skeleton represents a common site of metastases for osteotropic cancers such as prostate and breast tumors and novel therapeutic targets and new markers for the monitoring of bone lesions are urgently needed. The formation of bone metastases is a
Externí odkaz:
https://doaj.org/article/97729c9999b746eba2fc9eadb492e3f7
Autor:
Arjanneke F. van de Merbel, Geertje van der Horst, Maaike H. van der Mark, Janneke I. M. van Uhm, Erik J. van Gennep, Peter Kloen, Lijkele Beimers, Rob C. M. Pelger, Gabri van der Pluijm
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Urological malignancies, including prostate and bladder carcinoma, represent a major clinical problem due to the frequent occurrence of therapy resistance and the formation of incurable distant metastases. As a result, there is an urgent need for ver
Externí odkaz:
https://doaj.org/article/a34542d393314573b395802a3c5350a9
Autor:
Letizia Astrologo, Eugenio Zoni, Sofia Karkampouna, Peter C. Gray, Irena Klima, Joël Grosjean, Marie J. Goumans, Lukas J. A. C. Hawinkels, Gabri van der Pluijm, Martin Spahn, George N. Thalmann, Peter ten Dijke, Marianna Kruithof-de Julio
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Prostate cancer is the second most common cancer in men and lethality is normally associated with the consequences of metastasis rather than the primary tumor. Therefore, targeting the molecular pathways that underlie dissemination of primary tumor c
Externí odkaz:
https://doaj.org/article/e90b386966e644e587ad9e9540d0b6f2
Autor:
Alberto J Taurozzi, Ramprakash Beekharry, Michelle Wantoch, Marie-Christine Labarthe, Hannah F Walker, Robert I Seed, Matthew Simms, Greta Rodrigues, James Bradford, Geertje van der Horst, Gabri van der Pluijm, Anne T Collins
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188228 (2017)
Prostate cancer research is hampered by the lack of in vivo preclinical models that accurately reflect patient tumour biology and the clinical heterogeneity of human prostate cancer. To overcome these limitations we propagated and characterised a new
Externí odkaz:
https://doaj.org/article/5b025d09dca04afd9c6493e836c0b1c8
Autor:
Kostyantyn Semenchenko, Christine Wasylyk, Henry Cheung, Yves Tourrette, Peter Maas, Jack A Schalken, Gabri van der Pluijm, Bohdan Wasylyk
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159531 (2016)
Transcription factors have an important role in cancer but are difficult targets for the development of tumour therapies. These factors include the Ets family, and in this study Elk3 that is activated by Ras oncogene /Erk signalling, and is involved
Externí odkaz:
https://doaj.org/article/3ac99bd0b36c4880ac4aab36aca648c3
Autor:
Geertje van der Horst, Christel van den Hoogen, Jeroen T. Buijs, Henry Cheung, Henny Bloys, Rob C.M. Pelger, Giocondo Lorenzon, Bertrand Heckmann, Jean Feyen, Philippe Pujuguet, Roland Blanque, Philippe Clément-Lacroix, Gabri van der Pluijm
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 6, Pp 516-525 (2011)
Acquisition of an invasive phenotype by cancer cells is a requirement for bone metastasis. Transformed epithelial cells can switch to a motile, mesenchymal phenotype by epithelial-mesenchymal transition (EMT). Recently, it has been shown that EMT is
Externí odkaz:
https://doaj.org/article/41bee9f7edb2498aaf0b74f419a810f7
Autor:
Chiara Liverani, Federico La Manna, Arwin Groenewoud, Laura Mercatali, Gabri Van Der Pluijm, Federica Pieri, Davide Cavaliere, Alessandro De Vita, Chiara Spadazzi, Giacomo Miserocchi, Alberto Bongiovanni, Federica Recine, Nada Riva, Dino Amadori, Ennio Tasciotti, Ewa Snaar-Jagalska, Toni Ibrahim
Publikováno v:
Biology Open, Vol 6, Iss 2, Pp 309-309 (2017)
Externí odkaz:
https://doaj.org/article/fffd03a352bb4818917f3d0c62e2b137
Autor:
Berna C Özdemir, Janine Hensel, Chiara Secondini, Antoinette Wetterwald, Ruth Schwaninger, Achim Fleischmann, Wolfgang Raffelsberger, Olivier Poch, Mauro Delorenzi, Ramzi Temanni, Ian G Mills, Gabri van der Pluijm, George N Thalmann, Marco G Cecchini
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114530 (2014)
The reciprocal interaction between cancer cells and the tissue-specific stroma is critical for primary and metastatic tumor growth progression. Prostate cancer cells colonize preferentially bone (osteotropism), where they alter the physiological bala
Externí odkaz:
https://doaj.org/article/9704587b431f446cb1bafefc4a3deca6
Autor:
Geertje van der Horst, Lieke Bos, Maaike van der Mark, Henry Cheung, Bertrand Heckmann, Philippe Clément-Lacroix, Giocondo Lorenzon, Rob C M Pelger, Rob F M Bevers, Gabri van der Pluijm
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108464 (2014)
Low survival rates of metastatic cancers emphasize the need for a drug that can prevent and/or treat metastatic cancer. αv integrins are involved in essential processes for tumor growth and metastasis and targeting of αv integrins has been shown to
Externí odkaz:
https://doaj.org/article/34af0d028dec4ca7b237cdc0ec101173