Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gabor Smuk"'
Autor:
Edit Kiss, El Husseiny Mohamed Mahmud Abdelwahab, Anita Steib, Emoke Papp, Zsofia Torok, Laszlo Jakab, Gabor Smuk, Veronika Sarosi, Judit Erzsebet Pongracz
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background The predominant metastatic site of lung cancer (LC) is the brain. Although outdated, conventional cisplatin treatment is still the main therapeutic approach for patients with advanced non-small cell lung cancer (NSCLC), since targ
Externí odkaz:
https://doaj.org/article/77e7c0833e8c419db40af6a387aa00cd
Autor:
Elhusseiny Mohamed Mahmoud Abdelwahab, Judit Bovari-Biri, Gabor Smuk, Tunde Harko, Janos Fillinger, Judit Moldvay, Vera P. Krymskaya, Judit E. Pongracz
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundMutation in a tuberous sclerosis gene (TSC1 or 2) leads to continuous activation of the mammalian target of rapamycin (mTOR). mTOR activation alters cellular including vitamin A metabolism and retinoic acid receptor beta (RARβ) expression.
Externí odkaz:
https://doaj.org/article/2577f0df74994c4bac007a7fe93406a2
Feasibility study of in vitro drug sensitivity assay of advanced non-small cell lung adenocarcinomas
Autor:
Emoke Papp, Anita Steib, Elhusseiny MM Abdelwahab, Judit Meggyes-Rapp, Laszlo Jakab, Gabor Smuk, Erzsebet Schlegl, Judit Moldvay, Veronika Sárosi, Judit E Pongracz
Publikováno v:
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Background Despite improved screening techniques, diagnosis of lung cancer is often late and its prognosis is poor. In the present study, in vitro chemosensitivity of solid tumours and pleural effusions of lung adenocarcinomas were analysed and compa
Externí odkaz:
https://doaj.org/article/0ec02656f1d24dbaa9b72704827f65dc
Autor:
Luca Jaromi, Veronika Sárosi, Amina Soltani, Judit E. Pongracz, Veronika Csöngei, Zsofia Torok, Elhusseiny Mohamed Mahmud Abdelwahab, Monika Vesel, Gabor Smuk
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 5384, p 5384 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5384, p 5384 (2021)
Volume 22
Issue 10
Lung carcinoma is still the most common malignancy worldwide. One of the major subtypes of non-small cell lung cancer (NSCLC) is adenocarcinoma (AC). As driver mutations and hence therapies differ in AC subtypes, we theorized that the expression and
Autor:
Elhusseiny Mohamed Mahmoud Abdelwahab, Judit Bovari-Biri, Gabor Smuk, Tunde Harko, Janos Fillinger, Judit Moldvay, Vera P. Krymskaya, Judit E. Pongracz
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology
Frontiers in Oncology
BackgroundMutation in a tuberous sclerosis gene (TSC1 or 2) leads to continuous activation of the mammalian target of rapamycin (mTOR). mTOR activation alters cellular including vitamin A metabolism and retinoic acid receptor beta (RARβ) expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91714146880961da6b18aecb5bafaa94
https://doi.org/10.21203/rs.3.rs-41687/v2
https://doi.org/10.21203/rs.3.rs-41687/v2
Autor:
ElHusseiny MM Abdelwahab, Judit Bovari-Biri, Gabor Smuk, Tunde Harko, Janos Fillinger, Judit Moldvay, Vera Krymskaya, Judit E Pongracz
Background Mutation in a tuberous sclerosis gene (TSC1 or 2) leads to continuous activation of the mammalian target of rapamycin (mTOR). mTOR activation alters various cellular functions including cellular metabolism. In association with altered meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83e8371970d8e181c7b8bb8565733954
https://doi.org/10.21203/rs.3.rs-41687/v1
https://doi.org/10.21203/rs.3.rs-41687/v1
Autor:
Gabor Smuk, Ilse Chudoba, Gábor Pajor, Veronika Sárosi, László Pajor, Béla Kajtár, Tamás Tornóczky
Publikováno v:
Cytometry Part A. 93:653-661
EML4-ALK gene fusion (inv2(p21p23)) of non-small cell lung cancer (NSCLC) predisposes to tyrosine kinase inhibitor treatment. One of the gold standard diagnostics is the dual color (DC) break-apart (BA) FISH technique, however, the unusual closeness
Autor:
Emoke Papp, Veronika Sárosi, László Jakab, Gabor Smuk, Judit E. Pongracz, Anita Steib, E. Kiss, El Husseiny Mohamed Mahmud Abdelwahab, Zsofia Torok
Publikováno v:
Respiratory Research
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
BackgroundThe predominant metastatic site of lung cancer (LC) is the brain. Although outdated, conventional cisplatin treatment is still the main therapeutic approach for patients with advanced non-small cell lung cancer (NSCLC), since targeted thera
Feasibility study of in vitro drug sensitivity assay of advanced non-small cell lung adenocarcinomas
Autor:
Erzsebet Schlegl, Judit E. Pongracz, Emoke Papp, Veronika Sárosi, Judit Meggyes-Rapp, Elhusseiny Mm Abdelwahab, Gabor Smuk, Anita Steib, László Jakab, Judit Moldvay
Publikováno v:
BMJ Open Respiratory Research
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
BMJ Open Respiratory Research, Vol 7, Iss 1 (2020)
Background Despite improved screening techniques, diagnosis of lung cancer is often late and its prognosis is poor. In the present study, in vitro chemosensitivity of solid tumours and pleural effusions of lung adenocarcinomas were analysed and compa
Autor:
Gyorgy Miskei, D. Feller, Judit Rapp, Gabor Smuk, Judit E. Pongracz, Matyas Meggyes, Luca Jaromi, B. Duga, M. Vesel, Terézia László, Ivan Karner, E. Kiss
Publikováno v:
Respiratory Research
Background Lung cancer (LC) is still the most common cause of cancer related deaths worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of all LC cases but is not a single entity. It is now accepted that, apart from the characteristic driv