Zobrazeno 1 - 10
of 774
pro vyhledávání: '"Gabor G Kovacs"'
Autor:
Holger Hummerich, Helen Speedy, Tracy Campbell, Lee Darwent, Elizabeth Hill, Steven Collins, Christiane Stehmann, Gabor G Kovacs, Michael D Geschwind, Karl Frontzek, Herbert Budka, Ellen Gelpi, Adriano Aguzzi, Sven J van der Lee, Cornelia M van Duijn, Pawel P Liberski, Miguel Calero, Pascual Sanchez-Juan, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Stéphane Haïk, Jean-Phillipe Brandel, Angela Mammana, Sabina Capellari, Anna Poleggi, Anna Ladogana, Maurizio Pocchiari, Saima Zafar, Stephanie Booth, Gerard H Jansen, Aušrinė Areškevičiūtė, Eva Løbner Lund, Katie Glisic, Piero Parchi, Peter Hermann, Inga Zerr, Brian S Appleby, Jiri Safar, Pierluigi Gambetti, John Collinge, Simon Mead
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304528 (2024)
Human prion diseases are rare, transmissible and often rapidly progressive dementias. The most common type, sporadic Creutzfeldt-Jakob disease (sCJD), is highly variable in clinical duration and age at onset. Genetic determinants of late onset or slo
Externí odkaz:
https://doaj.org/article/a8105e366d44473aa02be9676f81d759
Autor:
Elizaveta Katorcha, Nuria Gonzalez-Montalban, Natallia Makarava, Gabor G Kovacs, Ilia V Baskakov
Publikováno v:
PLoS Pathogens, Vol 14, Iss 6, p e1007093 (2018)
The main risk of emergence of prion diseases in humans is associated with a cross-species transmission of prions of zoonotic origin. Prion transmission between species is regulated by a species barrier. Successful cross-species transmission is often
Externí odkaz:
https://doaj.org/article/12ec6c03efa5422ab896d8242055eadc
Autor:
Elizaveta Katorcha, Natallia Makarava, Young Jin Lee, Iris Lindberg, Mervyn J Monteiro, Gabor G Kovacs, Ilia V Baskakov
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006563 (2017)
Aggregation of misfolded proteins or peptides is a common feature of neurodegenerative diseases including Alzheimer's, Parkinson's, Huntington's, prion and other diseases. Recent years have witnessed a growing number of reports of overlap in neuropat
Externí odkaz:
https://doaj.org/article/36d4b9186f1e453987fd5242cc3c896d
Autor:
Yael Friedman-Levi, Zeev Meiner, Tamar Canello, Kati Frid, Gabor G Kovacs, Herbert Budka, Dana Avrahami, Ruth Gabizon
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006294 (2017)
[This corrects the article DOI: 10.1371/journal.ppat.1002350.].
Externí odkaz:
https://doaj.org/article/b0047a60fa684f8f82040fc447a3bc83
Autor:
Csaba eAdori, Swapnali eBarde, Nenad eBogdanovic, Mathias eUhlen, Rainer eReinscheid, Gabor G Kovacs, Tomas eHokfelt
Publikováno v:
Frontiers in Neuroanatomy, Vol 9 (2015)
Neuropeptide S (NPS) is a regulatory peptide with potent pharmacological effects. In rodents, NPS is expressed in a few pontine cell clusters. Its receptor (NPSR1) is, however, widely distributed in the brain. The anxiolytic and arousal-promoting eff
Externí odkaz:
https://doaj.org/article/fe999e7bc3b44e9084dbf0bfce0727f0
Autor:
Gabor G Kovacs, Philippe Gasque, Thomas Ströbel, Elisabeth Lindeck-Pozza, Michaela Strohschneider, James W Ironside, Herbert Budka, Marin Guentchev
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 1, Pp 21-28 (2004)
The central event in the neuropathological process of prion diseases (PrD) is the accumulation of abnormal prion protein accompanied by severe neuronal loss. Despite the infectious nature of these diseases, no prominent immune response has been detec
Externí odkaz:
https://doaj.org/article/30e6ab19450d4e158a037175fde60f34
Autor:
Pascual Sanchez-Juan, Matthew T Bishop, Gabor G Kovacs, Miguel Calero, Yurii S Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Ángel Carracedo, Sven J van der Lee, Thomas Ströbel, Fernando Rivadeneira, Albert Hofman, Stéphane Haïk, Onofre Combarros, José Berciano, Andre G Uitterlinden, Steven J Collins, Herbert Budka, Jean-Philippe Brandel, Jean Louis Laplanche, Maurizio Pocchiari, Inga Zerr, Richard S G Knight, Robert G Will, Cornelia M van Duijn
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123654 (2014)
We performed a genome-wide association (GWA) study in 434 sporadic Creutzfeldt-Jakob disease (sCJD) patients and 1939 controls from the United Kingdom, Germany and The Netherlands. The findings were replicated in an independent sample of 1109 sCJD an
Externí odkaz:
https://doaj.org/article/cce2b1a8c1a44c87b1539cdd95ccb3a7
Autor:
Natallia Makarava, Gabor G Kovacs, Regina Savtchenko, Irina Alexeeva, Herbert Budka, Robert G Rohwer, Ilia V Baskakov
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002419 (2011)
The transmissible agent of prion disease consists of a prion protein in its abnormal, β-sheet rich state (PrP(Sc)), which is capable of replicating itself according to the template-assisted mechanism. This mechanism postulates that the folding patte
Externí odkaz:
https://doaj.org/article/2680c7a0ba544af6b6a9468c9d03a2b3
Autor:
Yael Friedman-Levi, Zeev Meiner, Tamar Canello, Kati Frid, Gabor G Kovacs, Herbert Budka, Dana Avrahami, Ruth Gabizon
Publikováno v:
PLoS Pathogens, Vol 7, Iss 11, p e1002350 (2011)
Genetic prion diseases are late onset fatal neurodegenerative disorders linked to pathogenic mutations in the prion protein-encoding gene, PRNP. The most prevalent of these is the substitution of Glutamate for Lysine at codon 200 (E200K), causing gen
Externí odkaz:
https://doaj.org/article/75f3046067324cd1941d2b2086844c18
Autor:
Kurt Farrell, Megan A Iida, Jonathan D Cherry, Alicia Casella, Thor D Stein, Kevin F Bieniek, Jamie M Walker, Timothy E Richardson, Charles L White, Victor E Alvarez, Bertrand R Huber, Dennis W Dickson, Ricardo Insausti, Kristen Dams-O'Connor, Jean-Paul Vonsattel, Andy F Teich, Marla Gearing, Jonathan Glass, Juan C Troncoso, Matthew P Frosch, Bradley T Hyman, Melissa E Murray, Johannes Attems, Margaret E Flanagan, Qinwen Mao, M-Marsel Mesulam, Sandra Weintraub, Randy L Woltjer, Thao Pham, Julia Kofler, Julie A Schneider, Lei Yu, Dushyant P Purohit, Vahram Haroutunian, Patrick R Hof, Sam Gandy, Mary Sano, Thomas G Beach, Wayne Poon, Claudia H Kawas, María M Corrada, Robert A Rissman, Jeff Metcalf, Sara Shuldberg, Bahar Salehi, Peter T Nelson, John Q Trojanowski, Edward B Lee, David A Wolk, Corey T McMillan, C Dirk Keene, Caitlin S Latimer, Thomas J Montine, Gabor G Kovacs, Mirjam I Lutz, Peter Fischer, Richard J Perrin, Nigel J Cairns, Ann C McKee, John F Crary
Publikováno v:
Journal of neuropathology and experimental neurology. 81(10)
Chronic traumatic encephalopathy (CTE) is a tauopathy associated with repetitive mild head impacts characterized by perivascular hyperphosphorylated tau (p-tau) in neurofibrillary tangles (NFTs) and neurites in the depths of the neocortical sulci. In