Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Gabor G Illei"'
Autor:
Dominic Sinibaldi, Gabor G Illei, Wendy I White, S Sam Lim, Jason Cobb, Ahmad Akhgar, Lingmin Zeng, Alton B Farris, Monica Battle, David Chain, Jennifer A Cann
Publikováno v:
Lupus Science and Medicine, Vol 10, Iss 1 (2023)
Objective Lupus nephritis (LN) is diagnosed by biopsy, but longitudinal monitoring assessment methods are needed. Here, in this preliminary and hypothesis-generating study, we evaluate the potential for using urine proteomics as a non-invasive method
Externí odkaz:
https://doaj.org/article/96a750e6e45844798878b7804593e4aa
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e30679 (2012)
There is an increasing interest in using microRNAs (miRNA) as biomarkers in autoimmune diseases. They are easily accessible in many body fluids but it is controversial if they are circulating freely or are encapsulated in microvesicles, particularly
Externí odkaz:
https://doaj.org/article/9e81d38d15fd40e09f958eb3e23c4614
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19962 (2011)
Intercellular adhesion molecule-1 (ICAM-1) is involved in migration and co-stimulation of T and B cells. Membrane bound ICAM-1 is over expressed in the salivary glands (SG) of Sjögren's syndrome (SS) patients and has therefore been proposed as a pot
Externí odkaz:
https://doaj.org/article/e7e94273db88427781e2ce01653f7fed
Autor:
Junjun Luan, Congcong Jiao, Cong Ma, Yixiao Zhang, Xiangnan Hao, Guangyu Zhou, Jingqi Fu, Xingyu Qiu, Hongyu Li, Wei Yang, Gabor G. Illei, Jeffrey B. Kopp, Jingbo Pi, Hua Zhou
Publikováno v:
Oxidative medicine and cellular longevity. 2022
Recent studies have focused on nuclear-encoded circular RNAs (circRNAs) in kidney diseases, but little is known about mitochondrial circRNAs. Differentially expressed circRNAs were analyzed by RNA deep sequencing from lupus nephritis (LN) biopsies an
Autor:
Sencer Goklemez, Sarfaraz Hasni, Frances T Hakim, Paolo A Muraro, Filip Pirsl, Jeremy Rose, Sarfraz Memon, Daniel F Fowler, Seth M Steinberg, Eva H Baker, Sandya R Panch, Ronald Gress, Gabor G Illei, Peter E Lipsky, Steven Z Pavletic
Publikováno v:
Rheumatology (Oxford)
Objective Autologous haematopoietic cell transplantation (AHSCT) improves immunologic dysfunction in patients with SLE. However, the curative potential of this therapy remains uncertain. This study reports outcomes in SLE patients receiving a lymphod
Autor:
Ana P. Cotrim, Gabor G. Illei, Mayank Tandon, Eva J. Helmerhorst, Frank G. Oppenheim, John A. Chiorini, Paola Perez, M E Billings, James E. Melvin, Nikolay P. Nikolov, Shuying Liu, Marcelo A. Catalán, B J Baum, S J Danielides, Ilias Alevizos, CM Goldsmith, Changyu Zheng, Linda McCullagh
Publikováno v:
Gene therapy
We evaluated late effects of AdhAQP1 administration in five subjects in a clinical trial for radiation-induced salivary hypofunction (http://www.clinicaltrials.gov/ct/show/NCT00372320?order=). All were identified as initially responding to human aqua
Autor:
Yixiao Zhang, Qing Chang, Jingqi Fu, Weiwei Kong, Yanqiu Wang, Hua Zhou, Congcong Jiao, Jeffrey B. Kopp, Junjun Luan, Gabor G. Illei, Chengjie Chen, Detian Li, Jingbo Pi
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)
Background The prevalence of lupus nephritis (LN) remains high despite various emerging monoclonal antibodies against with targeting systemic lupus erythematosus (SLE). Renal fibrosis is the main feature of late stage LN, and novel therapeutic agents
Autor:
Junjun Luan, Jingqi Fu, Chengjie Chen, Congcong Jiao, Weiwei Kong, Yixiao Zhang, Chang, Qing, Yanqiu Wang, Detian Li, Gabor G. Illei, Kopp, Jeffrey, Jingbo Pi, Zhou, Hua
Additional file 1: Table S1. The clinical characteristics of LN patients. Table S2. The clinical characteristics of normal control human subjects. Table S3. Antibodies used in western blotting and immunofluorescence staining. Table S4. Sequence of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869827dba223e5092f3fcdebd58a828c
Autor:
Hwei Ling Ong, Indu S. Ambudkar, Shyh-Ing Jang, Ilias Alevizos, Gabor G. Illei, Mayank Tandon, Paola Perez, Alessia Gallo
Publikováno v:
EBioMedicine
EBioMedicine, Vol 10, Iss C, Pp 216-226 (2016)
EBioMedicine, Vol 10, Iss C, Pp 216-226 (2016)
Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease that is associated with inflammation and dysfunction of salivary and lacrimal glands. The molecular mechanism(s) underlying this exocrinopathy is not known, although the syndrome has
Autor:
Philip M. Carlucci, Sarthak Gupta, Barbara Dema, Alice Fike, Mariana J. Kaplan, Sungyoung Auh, Elaine Poncio, Zerai Manna, Gabor G. Illei, Ann Biehl, Nico Charles, Juan Rivera, Elizabeth Joyal, Meryl Waldman, Yenealem Temesgen-Oyelakin, Diana Chan, Richard M. Siegel, Sarfaraz Hasni, Michael Davis, Yinghui Shi, James E. Balow
Publikováno v:
Clinical Trials.
Background Previous evidence indicates a putative pathogenic role for IgE autoantibodies in systemic lupus erythematosus (SLE). We hypothesized that Omalizumab, a monoclonal antibody that binds IgE, will reduce SLE activity by decreasing circulating