Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Gabor, Szalai"'
Autor:
Christopher Butler, Samuel Sprowls, Gabor Szalai, Tasneem Arsiwala, Pushkar Saralkar, Benjamin Straight, Shea Hatcher, Evan Tyree, Michael Yost, William J. Kohler, Benjamin Wolff, Emily Putnam, Paul Lockman, Tuoen Liu
Publikováno v:
Translational Oncology, Vol 13, Iss 6, Pp - (2020)
Breast cancer patients presenting with symptomatic brain metastases have poor prognosis, and current chemotherapeutic agents are largely ineffective. In this study, we evaluated the hypomethylating agent azacitidine (AZA) for its potential as a novel
Externí odkaz:
https://doaj.org/article/ebf2afac0990498984f62850b8f84d41
Integrated Systems Biology Approach Identifies Novel Maternal and Placental Pathways of Preeclampsia
Autor:
Nandor Gabor Than, Roberto Romero, Adi Laurentiu Tarca, Katalin Adrienna Kekesi, Yi Xu, Zhonghui Xu, Kata Juhasz, Gaurav Bhatti, Ron Joshua Leavitt, Zsolt Gelencser, Janos Palhalmi, Tzu Hung Chung, Balazs Andras Gyorffy, Laszlo Orosz, Amanda Demeter, Anett Szecsi, Eva Hunyadi-Gulyas, Zsuzsanna Darula, Attila Simor, Katalin Eder, Szilvia Szabo, Vanessa Topping, Haidy El-Azzamy, Christopher LaJeunesse, Andrea Balogh, Gabor Szalai, Susan Land, Olga Torok, Zhong Dong, Ilona Kovalszky, Andras Falus, Hamutal Meiri, Sorin Draghici, Sonia S. Hassan, Tinnakorn Chaiworapongsa, Manuel Krispin, Martin Knöfler, Offer Erez, Graham J. Burton, Chong Jai Kim, Gabor Juhasz, Zoltan Papp
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Preeclampsia is a disease of the mother, fetus, and placenta, and the gaps in our understanding of the complex interactions among their respective disease pathways preclude successful treatment and prevention. The placenta has a key role in the patho
Externí odkaz:
https://doaj.org/article/b9ca02681b0146ddb64cc210e2dcee4b
Autor:
Tuoen Liu, Christopher Butler, Kelsey Donoughe, Lauren Forchette, William Sebastian, Gabor Szalai, Paul Lockman
Publikováno v:
Cancer Research. 83:2489-2489
Breast cancer is the second leading cause of cancer with the highest mortality rate in females in the United States. Late stage breast cancer can metastasize to different locations of the body, and patients with brain metastasis have a poor prognosis
Autor:
Gabor Szalai, Roberto Romero, Tinnakorn Chaiworapongsa, Yi Xu, Bing Wang, Hyunyoung Ahn, Zhonghui Xu, Po Jen Chiang, Birgitta Sundell, Rona Wang, Yang Jiang, Olesya Plazyo, Mary Olive, Adi L Tarca, Zhong Dong, Faisal Qureshi, Zoltan Papp, Sonia S Hassan, Edgar Hernandez-Andrade, Nandor Gabor Than
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0119547 (2015)
OBJECTIVE:Most anti-angiogenic preeclampsia models in rodents utilized the overexpression of a truncated soluble fms-like tyrosine kinase-1 (sFlt-1) not expressed in any species. Other limitations of mouse preeclampsia models included stressful blood
Externí odkaz:
https://doaj.org/article/201c41f2001847689d551bd72292cc94
Publikováno v:
Cancer Research. 82:2363-2363
Among all cancer types, breast cancer has the highest incidence rate and second highest mortality rate in females in the United States. Breast cancer patients with brain metastasis have a poor prognosis, with a median survival time of less than 1 yea
Autor:
Gabor Szalai, Yi Xu, Roberto Romero, Tinnakorn Chaiworapongsa, Zhonghui Xu, Po Jen Chiang, Hyunyoung Ahn, Birgitta Sundell, Olesya Plazyo, Yang Jiang, Mary Olive, Bing Wang, Suzanne M Jacques, Faisal Qureshi, Adi L Tarca, Offer Erez, Zhong Dong, Zoltan Papp, Sonia S Hassan, Edgar Hernandez-Andrade, Nandor Gabor Than
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e110867 (2014)
ObjectiveSoluble fms-like tyrosine kinase (sFlt)-1-e15a, a primate-specific sFlt-1-isoform most abundant in the human placenta in preeclampsia, can induce preeclampsia in mice. This study compared the effects of full-length human (h)sFlt-1-e15a with
Externí odkaz:
https://doaj.org/article/f8ccd1944d854561b164b551c0cd5bb9
Autor:
Anna Csiszar, Magor Papp, Stefano Tarantini, Andrej Podlutsky, Gabor Szalai, Teresa G. Valencak, Zoltan Ungvari, Vince Fazekas-Pongor
Publikováno v:
GeroScience
The current COVID-19 pandemic, caused by the highly contagious respiratory pathogen SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has already claimed close to three million lives. SARS-CoV-2 is a zoonotic disease: it emerged from a ba
Publikováno v:
Cureus
Kounis syndrome (KS) is defined as an allergic or hypersensitivity reaction leading to coronary vasospasm and acute coronary syndrome. The inflammatory mediators released during the body's reaction to an allergen causes vasoconstriction, plaque ruptu
Autor:
Shea Hatcher, Tasneem Arsiwala, Evan Tyree, Emily Putnam, Samuel A. Sprowls, Pushkar Saralkar, Tuoen Liu, Christopher Butler, Michael Yost, Benjamin Straight, Paul R. Lockman, William J. Kohler, Benjamin Wolff, Gabor Szalai
Publikováno v:
Translational Oncology, Vol 13, Iss 6, Pp-(2020)
Translational Oncology
Translational Oncology
Breast cancer patients presenting with symptomatic brain metastases have poor prognosis, and current chemotherapeutic agents are largely ineffective. In this study, we evaluated the hypomethylating agent azacitidine (AZA) for its potential as a novel
Autor:
András Szilágyi, Petronella Hupuczi, Eszter Tóth, Zsuzsanna Darula, Gabor Szalai, Katalin A. Kékesi, Offer Erez, Zsolt Gelencser, Zoltán Papp, Beáta Hargitai, Tibor Krenács, Szilvia Szabo, Nandor Gabor Than, Katalin Karaszi, Ilona Kovalszky, Roberto Romero, Andrea Balogh, Éva Hunyadi-Gulyás, Adi L. Tarca, Yi Xu, Gábor Juhász
Publikováno v:
Placenta
Introduction Placental Protein 1 (PP1), PP8, and PP22 were isolated from the placenta. Herein, we aimed to identify PP1, PP8, and PP22 proteins and their placental and trophoblastic expression patterns to reveal potential involvement in pregnancy com