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Akademický článek

Evolutionary insights from a genetically divergent hantavirus harbored by the European common mole (Talpa europaea).

Autor: Hae Ji Kang, Shannon N Bennett, Laarni Sumibcay, Satoru Arai, Andrew G Hope, Gabor Mocz, Jin-Won Song, Joseph A Cook, Richard Yanagihara

Publikováno v: PLoS ONE, Vol 4, Iss 7, p e6149 (2009)

BACKGROUND:The discovery of genetically distinct hantaviruses in shrews (Order Soricomorpha, Family Soricidae) from widely separated geographic regions challenges the hypothesis that rodents (Order Rodentia, Family Muridae and Cricetidae) are the pri

Externí odkaz: https://doaj.org/article/fa17677f183149d6b29ea05db60965e4

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Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation

Autor: Gabor Mocz, Ingo Lange, André S. Bachmann, Dirk Geerts, David J. Feith, Jan Koster

Publikováno v: Journal of molecular biology, 426(2), 332-346. Academic Press Inc.
Lange, I, Geerts, D, Feith, D J, Mocz, G, Koster, J & Bachmann, A S 2014, ' Novel interaction of ornithine decarboxylase with sepiapterin reductase regulates neuroblastoma cell proliferation ', Journal of Molecular Biology, vol. 426, no. 2, pp. 332-46 . https://doi.org/10.1016/j.jmb.2013.09.037
Journal of Molecular Biology, 426(2), 332-46. Academic Press Inc.

Ornithine decarboxylase (ODC) is the sentinel enzyme in polyamine biosynthesis. Both ODC and polyamines regulate cell division, proliferation, and apoptosis. Sepiapterin reductase (SPR) catalyzes the last step in the biosynthesis of tetrahydrobiopter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6ed0f0f46b2ce87df6690458082125
https://doi.org/10.1016/j.jmb.2013.09.037

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Molecular phylogeny of a newfound hantavirus in the Japanese shrew mole (Urotrichus talpoides)

Autor: Gabor Mocz, Richard Yanagihara, Jiro Arikawa, Satoru Arai, Nobuhiko Okabe, Hae Ji Kang, Satoshi D. Ohdachi, Mitsuhiko Asakawa

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America = Proceedings of the National Academy of Sciences of the United States of America. 105(42):16296-16301

Recent molecular evidence of genetically distinct hantaviruses in shrews, captured in widely separated geographical regions, corroborates decades-old reports of hantavirus antigens in shrew tissues. Apart from challenging the conventional view that r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e8c53912f3226d4b7a06e761e07b25
http://hdl.handle.net/10659/2236

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Effect of sulfasalazine on human neuroblastoma: analysis of sepiapterin reductase (SPR) as a new therapeutic target

Autor: Lisette P. Yco, Dirk Geerts, André S. Bachmann, Jan Koster, Gabor Mocz

Publikováno v: BMC Cancer
BMC cancer, 15(1). BioMed Central
BMC Cancer, 15. BioMed Central
Yco, L P, Geerts, D, Mocz, G, Koster, J & Bachmann, A S 2015, ' Effect of sulfasalazine on human neuroblastoma : analysis of sepiapterin reductase (SPR) as a new therapeutic target ', BMC Cancer, vol. 15, pp. 477 . https://doi.org/10.1186/s12885-015-1447-y

BACKGROUND: Neuroblastoma (NB) is an aggressive childhood malignancy in children up to 5 years of age. High-stage tumors frequently relapse even after aggressive multimodal treatment, and then show therapy resistance, typically resulting in patient d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c614c9c4411a7e0410fb83e87b95e7
http://europepmc.org/articles/PMC4475614

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Information Content of Fluorescence Polarization and Anisotropy

Autor: Gabor Mocz

Publikováno v: Journal of Fluorescence. 16:511-524

The equality of information content in fluorescence polarization and emission anisotropy is a common assumption and the two quantities are used according to practical considerations. However, an information-theoretic analysis presented here reveals t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a53a9fe5e74baf6a00a75ea31e7d64
https://doi.org/10.1007/s10895-006-0095-7

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Genomic organization, characterization, and molecular 3D model of GDE1, a novel mammalian glycerophosphoinositol phosphodiesterase

Autor: Gabor Mocz, Frederick F. Duennebier, André S. Bachmann

Publikováno v: Gene. 371:144-153

Glycerophosphodiester phosphodiesterase (GDPD) catalyzes the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. A mammalian glycerophosphoinositol phosphodiesterase, GDE1/MIR16, was recently identified as an interacting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d11187226f4eca8a663661bb00130cf6
https://doi.org/10.1016/j.gene.2005.11.023

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Model for the Motor Component of Dynein Heavy Chain Based on Homology to the AAA Family of Oligomeric ATPases

Autor: Gabor Mocz, I. R. Gibbons

Publikováno v: Structure. 9:93-103

Background: Recent iterative methods for sequence alignment have indicated that the 380 kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases . These alignments indicate that the core of the 380 kDa motor unit contains a concate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c664920b20af7a4cc514e593bed7d68
https://doi.org/10.1016/s0969-2126(00)00557-8

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A Changing Research and Publication Landscape for Biochemistry

Autor: Gabor Mocz

Publikováno v: Biochemistry Insights, Vol 1, Pp 1-3 (2008)
Biochemistry Insights, Vol 1 (2008)

This introductory editorial hopes to convey three points to its audience. First, it provides an overview of the new, peer-reviewed, open access journal Biochemistry Insights published by Libertas Academica. Second, it summarizes the benefits of open

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deffae8c0c3df926558e3c7007d7c1e1
http://www.la-press.com/a-changing-research-and-publication-landscape-for-biochemistry-a640

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Probing the Nucleotide Binding Sites of Axonemal Dynein with the Fluorescent Nucleotide Analogue 2‘(3‘)-O-(-N-Methylanthraniloyl)-adenosine 5‘-Triphosphate

Autor: Michael K. Helms, David M. Jameson, I. R. Gibbons, Gabor Mocz

Publikováno v: Biochemistry. 37:9862-9869

MantATP [2'(3')-O-(-N-methylanthraniloyl)-adenosine 5'-triphosphate] was employed as a fluorescence probe of the nucleotide-binding sites of dynein from sea urchin sperm flagella. MantATP binds specifically with enhanced fluorescence (approximately 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c22b3df51222216dad68f2cf626096c
https://doi.org/10.1021/bi9730184

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Fluorescence techniques in analysis of protein-ligand interactions

Autor: Gabor, Mocz, Justin A, Ross

Publikováno v: Methods in molecular biology (Clifton, N.J.). 1008

Fluorescence spectroscopy may serve as a universal tool for the study of protein-ligand interactions. Applications of fluorometry have made use of various aspects of fluorescence such as intensity, emission and excitation spectra, lifetime, quantum y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7fde6b80fa10b596c3ffc25d7bcb931b
https://pubmed.ncbi.nlm.nih.gov/23729253

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