Zobrazeno 1 - 10 of 357 pro vyhledávání: '"Gabitova L."'
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Akademický článek
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Screening of conditionally reprogrammed patient-derived carcinoma cells identifies ERCC3-MYC interactions as a target in pancreatic cancer
Autor: Beglyarova N., Banina E., Zhou Y., Mukhamadeeva R., Andrianov G., Bobrov E., Lysenko E., Skobeleva N., Gabitova L., Restifo D., Pressman M., Serebriiskii I., Hoffman J., Paz K., Behrens D., Khazak V., Jablonski S., Golemis E., Weiner L., Astsaturov I.
Publikováno v: SCOPUS10780432-2016-22-24-SID85006985653
©2016 AACR.Purpose: Even when diagnosed prior to metastasis, pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy with almost 90% lethality, emphasizing the need for new therapies optimally targeting the tumors of individual patients.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7a24c70a0a33fda419bb95f0464b9e62
https://openrepository.ru/article?id=222153
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4
Akademický článek
Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast-Driven Nutritional Support and Immunosuppression.
Autor: Francescone R; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Barbosa Vendramini-Costa D; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Franco-Barraza J; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Wagner J; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Muir A; Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Ben May Department for Cancer Research, University of Chicago, Chicago, Illinois., Lau AN; Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts., Gabitova L; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Pazina T; Blood Cell and Development and Function Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Gupta S; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Luong T; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Rollins D; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Malik R; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Thapa RJ; Blood Cell and Development and Function Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Restifo D; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Zhou Y; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Biostatistics and Bioinformatics Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Cai KQ; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Histopathology Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Hensley HH; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Small Animal Imaging Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Tan Y; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Genomics Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Kruger WD; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Devarajan K; Biostatistics and Bioinformatics Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Balachandran S; Blood Cell and Development and Function Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Klein-Szanto AJ; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Histopathology Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Wang H; Division of Pathology/Lab Medicine, Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., El-Deiry WS; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island., Vander Heiden MG; Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts.; Dana-Farber Cancer Institute, Boston, Massachusetts., Peri S; Biostatistics and Bioinformatics Facility, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Campbell KS; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Blood Cell and Development and Function Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Astsaturov I; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.; Molecular Therapeutics Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania., Cukierman E; Cancer Biology Program, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania. edna.cukierman@fccc.edu.; Marvin and Concetta Greenberg Pancreatic Cancer Institute, Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Publikováno v: Cancer discovery [Cancer Discov] 2021 Feb; Vol. 11 (2), pp. 446-479. Date of Electronic Publication: 2020 Oct 30.
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Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR
Autor: Gabitova L., Restifo D., Gorin A., Manocha K., Handorf E., Yang D., Cai K., Klein-Szanto A., Cunningham D., Kratz L., Herman G., Golemis E., Astsaturov I.
Publikováno v: SCOPUS-2015-12-11-SID84942821941
© 2015 The Authors. Meiosis-activating sterols (MAS) are substrates of SC4MOL and NSDHL in the cholesterol pathway and are important for normal organismal development. Oncogenic transformation by epidermal growth factor receptor (EGFR) or RAS increa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::38ef20896ed1c1ff56d585937a722d45
https://openrepository.ru/article?id=676371
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Molecular pathways: Sterols and receptor signaling in cancer
Autor: Gabitova L., Gorin A., Astsaturov I.
Publikováno v: SCOPUS10780432-2014-20-1-SID84892170909
Accelerated cholesterol and lipid metabolism are the hallmarks of cancer and contribute to malignant transformation due to the obligatory requirement for cholesterol for the function of eukaryotic membranes. To build new membranes and maintain active
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::52b57cca0543e1ff0366b5807a824286
https://openrepository.ru/article?id=209006
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7
Akademický článek
Extracellular vesicle‐packaged lncRNA from cancer‐associated fibroblasts promotes immune evasion by downregulating HLA‐A in pancreatic cancer.
Autor: Yao, Hanming1,2,3 (AUTHOR), Huang, Chengzhi4 (AUTHOR), Zou, Jinmao2,3 (AUTHOR), Liang, Weiling2 (AUTHOR), Zhao, Yue2,3 (AUTHOR), Yang, Kege2,3 (AUTHOR), Zhong, Ziyi2,3 (AUTHOR), Zhou, Shurui2,3 (AUTHOR), Li, Jiajia5 (AUTHOR), Li, Yaqing2,3 (AUTHOR) liyaq3@mail2.sysu.edu.cn, Xu, Lishu1 (AUTHOR) xulishu70@163.com, Huang, Kaihong2,3 (AUTHOR) huangkh@mail.sysu.edu.cn, Lian, Guoda2,3 (AUTHOR) liangd28@mail.sysu.edu.cn
Publikováno v: Journal of Extracellular Vesicles. Jul2024, Vol. 13 Issue 7, p1-25. 25p.
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8
Akademický článek
The role of ATP‐binding cassette subfamily G member 1 in tumor progression.
Autor: Xinyi, Xu1 (AUTHOR), Gong, Yang1,2,3 (AUTHOR) yanggong@fudan.edu.cn
Publikováno v: Cancer Medicine. Jun2024, Vol. 13 Issue 12, p1-11. 11p.
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9
Akademický článek
CAFs-Associated Genes (CAFGs) in Pancreatic Ductal Adenocarcinoma (PDAC) and Novel Therapeutic Strategy.
Autor: Yamashita, Keishi1 (AUTHOR) keishi23@med.kitasato-u.ac.jp, Kumamoto, Yusuke2 (AUTHOR) 110kumakuma@gmail.com
Publikováno v: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p6003. 18p.
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10
Akademický článek
Chemical Inhibition of Sterol Biosynthesis.
Autor: Peeples, Eric S.1,2,3 (AUTHOR) epeeples@childrensnebraska.org, Mirnics, Karoly2,4,5,6 (AUTHOR), Korade, Zeljka1,2,4 (AUTHOR)
Publikováno v: Biomolecules (2218-273X). Apr2024, Vol. 14 Issue 4, p410. 20p.
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