Zobrazeno 1 - 10
of 193
pro vyhledávání: '"Gabelica, Valerie"'
Autor:
Ghosh, Anirban, Trajkovski, Marko, Teulade-Fichou, Marie-paule, Gabelica, Valérie, Plavec, Janez
Publikováno v:
Angewandte Chemie International Edition, 2022, 61 (40), pp.e202207384
Human telomeric G-quadruplex DNA structures are attractive anticancer drug targets, but the target's polymorphism complicates the drug design: different ligands prefer different folds, and very few complexes have been solved at high resolution. Here
Externí odkaz:
http://arxiv.org/abs/2306.04291
Autor:
Gabelica, Valérie
Publikováno v:
Accounts of Chemical Research, 2021, 54 (19), pp.3691-3699
While studying nucleic acids to reveal the weak interactions responsible for their three-dimensional structure and for their interactions with drugs, we also contributed to the field of biomolecular mass spectrometry, both in terms of fundamental und
Externí odkaz:
http://arxiv.org/abs/2306.04260
Autor:
Guzmán-Lorite, Miriam, Rosu, Frédéric, Marina, María Luisa, García, María Concepción, Gabelica, Valérie
Publikováno v:
In Analytica Chimica Acta 22 April 2024 1299
DNA and proteins are chiral: their three-dimensional structure cannot be superimposed with its mirror image. Circular dichroism spectroscopy is widely used to characterize chiral compounds, but data interpretation is difficult in the case of mixtures
Externí odkaz:
http://arxiv.org/abs/2002.01299
Akademický článek
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Autor:
Tran, Vienna T., Turek-Herman, Joshua, Ferreira, Michelle, Martin, Kailey N., Beseiso, Dana, Williams, Benjamin R., Rosu, Frederic, Gabelica, Valérie, Burgmayer, Sharon J. Nieter, Yatsunyk, Liliya A.
Publikováno v:
In Journal of Inorganic Biochemistry December 2023 249
In solution, UV-vis spectroscopy is often used to investigate structural changes in biomolecules (i.e., nucleic acids), owing to changes in the environment of their chromophores (i.e., the nucleobases). Here we address whether action spectroscopy cou
Externí odkaz:
http://arxiv.org/abs/1903.04412
Publikováno v:
Physical Chemistry Chemical Physics, Royal Society of Chemistry, 2018, 20, pp.26597-26607
Phosphorylation is one of the most important protein modifications, and electron-transfer dissociation tandem mass spectrometry (ETD-MS/MS) is a potentially useful method for the sequencing of phosphopeptides, including determination of the phosphory
Externí odkaz:
http://arxiv.org/abs/1811.10445
Publikováno v:
J. Phys. Chem. Lett. (2018) 9(22): 6605-6610
Hydrogen bonding between nucleobases produces diverse DNA structural motifs, including canonical duplexes, guanine (G) quadruplexes and cytosine (C) i-motifs. Incorporating metal-mediated base pairs into nucleic acid structures can introduce new func
Externí odkaz:
http://arxiv.org/abs/1809.01241
Publikováno v:
J. Am. Soc. Mass Spectrom., 2018
The meaningful comparison of ion mobility (IM) results and of collision cross section (CCS) values on different platforms is a prerequisite for using CCS for identification or structural assignment. The amount of internal energy imparted to the ions
Externí odkaz:
http://arxiv.org/abs/1805.01735