Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Gabby, Rudenko"'
Autor:
Nicolas Chofflet, Yusuke Naito, Anthony John Pastore, Nirmala Padmanabhan, Phuong Trang Nguyen, Christian Poitras, Benjamin Feller, Nayoung Yi, Jeremie Van Prooijen, Husam Khaled, Benoit Coulombe, Steven J. Clapcote, Steve Bourgault, Tabrez J. Siddiqui, Gabby Rudenko, Hideto Takahashi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and postsynaptic assembly. How these extracellular interactions translate into intracellular
Externí odkaz:
https://doaj.org/article/b0e5ea6d61414d33a1c87b6f1bb93555
Autor:
Zhou Yin, Harikanth Venkannagari, Haley Lynch, Galina Aglyamova, Mukund Bhandari, Mischa Machius, Eric J. Nestler, Alfred J. Robison, Gabby Rudenko
Publikováno v:
Current Research in Structural Biology, Vol 2, Iss , Pp 1-13 (2020)
ΔFosB is a highly stable transcription factor that accumulates in specific brain regions upon chronic exposure to drugs of abuse, stress, or seizures, and mediates lasting behavioral responses. ΔFosB reportedly heterodimerizes with JunD forming a c
Externí odkaz:
https://doaj.org/article/2ba2f505e8a0466988fa56318724b382
Autor:
Peter A. Meyer, Stephanie Socias, Jason Key, Elizabeth Ransey, Emily C. Tjon, Alejandro Buschiazzo, Ming Lei, Chris Botka, James Withrow, David Neau, Kanagalaghatta Rajashankar, Karen S. Anderson, Richard H. Baxter, Stephen C. Blacklow, Titus J. Boggon, Alexandre M. J. J. Bonvin, Dominika Borek, Tom J. Brett, Amedeo Caflisch, Chung-I Chang, Walter J. Chazin, Kevin D. Corbett, Michael S. Cosgrove, Sean Crosson, Sirano Dhe-Paganon, Enrico Di Cera, Catherine L. Drennan, Michael J. Eck, Brandt F. Eichman, Qing R. Fan, Adrian R. Ferré-D'Amaré, J. Christopher Fromme, K. Christopher Garcia, Rachelle Gaudet, Peng Gong, Stephen C. Harrison, Ekaterina E. Heldwein, Zongchao Jia, Robert J. Keenan, Andrew C. Kruse, Marc Kvansakul, Jason S. McLellan, Yorgo Modis, Yunsun Nam, Zbyszek Otwinowski, Emil F. Pai, Pedro José Barbosa Pereira, Carlo Petosa, C. S. Raman, Tom A. Rapoport, Antonina Roll-Mecak, Michael K. Rosen, Gabby Rudenko, Joseph Schlessinger, Thomas U. Schwartz, Yousif Shamoo, Holger Sondermann, Yizhi J. Tao, Niraj H. Tolia, Oleg V. Tsodikov, Kenneth D. Westover, Hao Wu, Ian Foster, James S. Fraser, Filipe R. N C. Maia, Tamir Gonen, Tom Kirchhausen, Kay Diederichs, Mercè Crosas, Piotr Sliz
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The validation and analysis of X-ray crystallographic data is essential for reproducibility and the development of crystallographic methods. Here, the authors describe a repository for crystallographic datasets and demonstrate some of the ways it cou
Externí odkaz:
https://doaj.org/article/72383da3679147f9a2668c703d709d2e
Autor:
Gabby Rudenko
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Synapses play a critical role in establishing and maintaining neural circuits, permitting targeted information transfer throughout the brain. A large portfolio of synaptic adhesion/organizing molecules (SAMs) exists in the mammalian brain involved in
Externí odkaz:
https://doaj.org/article/66dbe8a453784d7fbbfc2048f9d5e98e
Autor:
Alvaro O. Ardiles, Andreas M. Grabrucker, Francisco G. Scholl, Gabby Rudenko, Tiziana Borsello
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
Externí odkaz:
https://doaj.org/article/dd65ad9c042a4a048660d738eb4e5c74
Autor:
Ashwani Kumar, Galina Aglyamova, Yun Young Yim, Aaron O Bailey, Haley M Lynch, Reid T Powell, Nghi D Nguyen, Zachary Rosenthal, Wen-Ning Zhao, Yi Li, Jianping Chen, Shanghua Fan, Hubert Lee, William K Russell, Clifford Stephan, Alfred J Robison, Stephen J Haggarty, Eric J Nestler, Jia Zhou, Mischa Machius, Gabby Rudenko
Publikováno v:
Nucleic acids research. 50(16)
The AP1 transcription factor ΔFOSB, a splice variant of FOSB, accumulates in the brain in response to chronic insults such as exposure to drugs of abuse, depression, Alzheimer's disease and tardive dyskinesias, and mediates subsequent long-term neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fc59d86aaf25f7d96823a3e2e4dc06
https://pubmed.ncbi.nlm.nih.gov/36039764
https://pubmed.ncbi.nlm.nih.gov/36039764
Autor:
Hubert Lee, Nicolas Chofflet, Jianfang Liu, Shanghua Fan, Zhuoyang Lu, Martin Resua Rojas, Patrick Penndorf, Aaron O. Bailey, William K. Russell, Mischa Machius, Gang Ren, Hideto Takahashi, Gabby Rudenko
Publikováno v:
The Journal of biological chemistry, vol 299, iss 4
MDGAs (MAM domain-containing glycosylphosphatidylinositol anchors) are synaptic cell surface molecules that regulate the formation of trans-synaptic bridges between neurexins (NRXNs) and neuroligins (NLGNs), which promote synaptic development. Mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c031473a579853ed95ed2d78b1c1d4
https://doi.org/10.1016/j.jbc.2023.104586
https://doi.org/10.1016/j.jbc.2023.104586
Autor:
Jonathan D. Hommel, Mischa Machius, Shanghua Fan, Scott A. Rush, Hong Sun, Harikanth Venkannagari, Gabby Rudenko, Hubert Lee, Anurag Misra, Suchithra Seshadrinathan, James M. Kasper
Publikováno v:
J Mol Biol
Neuronal growth regulator 1 (NEGR1) and neurotrimin (NTM) are abundant cell-surface proteins found in the brain and form part of the IgLON (Immunoglobulin LSAMP, OBCAM, Neurotrimin) family. In humans, NEGR1 is implicated in obesity and mental disorde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2cf08f77c47fc111011c0fd6fe8256
https://doi.org/10.1016/j.jmb.2020.07.014
https://doi.org/10.1016/j.jmb.2020.07.014
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 2, Pp 297-308 (2010)
The LDL receptor (LDL-R) mediates cholesterol metabolism in humans by binding and internalizing cholesterol transported by LDL. Several different molecular mechanisms have been proposed for the binding of LDL to LDL-R at neutral plasma pH and for its
Externí odkaz:
https://doaj.org/article/e173202446d34db4b6d1c366112a4a0f
Publikováno v:
Structure
Summary Hevin is secreted by astrocytes and its synaptogenic effects are antagonized by the related protein, SPARC. Hevin stabilizes neurexin-neuroligin transsynaptic bridges in vivo. A third protein, membrane-tethered MDGA, blocks these bridges. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718c59a1fd8d8d8821ae5ed379cfce5a
https://europepmc.org/articles/PMC8254758/
https://europepmc.org/articles/PMC8254758/
