Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ga Young You"'
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 68:372-381
We investigated the antiwrinkle effects of cultured human fibroblasts and adipose-derived stem cells (ADSCs) and the mechanisms underlying the reduction of wrinkles in photoaged skin. The fibroblasts and ADSCs were isolated from human tissue and cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7fc5d371575ca316dcd2ff7faef35d
https://doi.org/10.1016/j.bjps.2014.10.045
https://doi.org/10.1016/j.bjps.2014.10.045
Autor:
Ji Wook Moon, Hye Jeong Lee, Sun Hwa Park, Sha Jie, Ga Young You, Su Jin Kim, Hyeon Soo Kim, Nami Kim, Soo Kyung Lee, Ji Hae Kim, Jung Ok Lee
Publikováno v:
Cellular Signalling. 25:2558-2565
Metformin is known to stimulate glucose uptake, but the mechanism for this action is not fully understood. In this study, AMPK activators (AICAR and metformin) increased the expression of T-lymphoma invasion and metastasis-inducing protein-1 (Tiam-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70800f1f9c9bf774e90d5f2c77b440dc
https://doi.org/10.1016/j.cellsig.2013.08.018
https://doi.org/10.1016/j.cellsig.2013.08.018
Autor:
Sha Jie, Ji Wook Moon, Yong Woo Lee, Nami Kim, Ho Jin Kang, Jung Ok Lee, Sun Hwa Park, Hyeon Soo Kim, Soo Kyung Lee, Ji Hae Kim, Ga Young You, Su Jin Kim, Yongchul Lim
Publikováno v:
Journal of Biological Chemistry. 288:4673-4680
It is known that the activity of AMP-activated protein kinase (AMPKα2) was depressed under high glucose conditions. However, whether protein expression of AMPKα2 is also down-regulated or not remains unclear. In this study, we showed that the expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6916d02543d6a617c520ab8621bc3c4e
https://doi.org/10.1074/jbc.m112.406009
https://doi.org/10.1074/jbc.m112.406009
Autor:
Ga Young You, Su Jin Kim, Nami Kim, Jung Ok Lee, Ho Jin Kang, Jie Sha, Hyeon Soo Kim, Sun Hwa Park, Ji Wook Moon, Ji Hae Kim, Soo Kyung Lee, Yong Woo Lee
Publikováno v:
Cellular Signalling. 24:2329-2336
Coenzyme Q10(CoQ10) is a known anti-adipogenic factor. However, the mechanism by which CoQ10 acts is unclear. In this study, we found that CoQ10 increased the phosphorylation of AMP-activated protein kinase (AMPK) in 3T3-L1preadipocytes. CoQ10 induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b0fda1c12fbaa968448ee70ca4d510
https://doi.org/10.1016/j.cellsig.2012.07.022
https://doi.org/10.1016/j.cellsig.2012.07.022
Autor:
Hyeon Soo Kim, Sun Hwa Park, Jung Ok Lee, Ga Young You, Su Jin Kim, Pann-Ghill Suh, Ji Wook Moon, Jin Hee Jung, Kyung Ok Uhm, Ji Man Park, Soo Kyung Lee, Ji Hae Kim
Publikováno v:
Journal of Cellular Biochemistry. 112:1259-1267
Insulin resistance is the primary cause responsible for type 2 diabetes. Phosphatase and tensin homolog (PTEN) plays a negative role in insulin signaling and its inhibition improves insulin sensitivity. Metformin is a widely used insulin-sensitizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d504baf6de7fc843aa87b20f346b71a
https://doi.org/10.1002/jcb.23000
https://doi.org/10.1002/jcb.23000
Autor:
Jung Ok Lee, Sun Hwa Park, Soo Kyung Lee, Jin Hee Jung, Ga Young You, Su Jin Kim, Kyung Ok Uhm, Ji Hae Kim, Hyeon Soo Kim
Publikováno v:
Journal of Cellular Physiology. 226:974-981
Metformin is a major oral anti-diabetic drug and is known as an insulin sensitizer. However, the mechanism by which metformin acts is unclear. In this study, we found that AICAR, an AMPK activator, and metformin increased the expression of Rab4 mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092fb56afddcb099b41e4678179c6f6c
https://doi.org/10.1002/jcp.22410
https://doi.org/10.1002/jcp.22410
Publikováno v:
The Journal of craniofacial surgery. 26(6)
UNLABELLED Autologous adipose-derived stem cells have shown great promise in applications that treat photodamaged skin. Adipose-derived stem cells also have an antiwrinkle effect; consequently, they have become a topic of primary interest. Nude mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46a414e4066d0efeba57a51be1a5bd7
https://pubmed.ncbi.nlm.nih.gov/26267568
https://pubmed.ncbi.nlm.nih.gov/26267568
Autor:
Ji Wook Moon, Nami Kim, Ji Hae Kim, Soo Kyung Lee, Sun Hwa Park, Hyeon Soo Kim, Ga Young You, Su Jin Kim, Jung Ok Lee
Publikováno v:
The Journal of biological chemistry. 287(53)
Metformin is a leading oral anti-diabetes mellitus medication and is known to stimulate GLUT4 translocation. However, the mechanism by which metformin acts is still largely unknown. Here, we showed that short time treatment with metformin rapidly inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5c4293ba08444cdc6717d14383845a
https://pubmed.ncbi.nlm.nih.gov/23135276
https://pubmed.ncbi.nlm.nih.gov/23135276
Autor:
Ji Hae Kim, Ga Young You, Su Jin Kim, Jung Ok Lee, Hyeon Soo Kim, Nami Kim, Sun Hwa Park, Jie Sha, Ji Wook Moon, Soo Kyung Lee
Publikováno v:
Cellular signalling. 25(4)
Celastrol, an anti-oxidant flavonoid that is widely distributed in the plant kingdom, has been suggested to have chemopreventive effects on cancer cells: however, the mechanism of this process is not completely understood. In this study, we found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7547b69fd828783b256eae3e74d52e40
https://pubmed.ncbi.nlm.nih.gov/23266469
https://pubmed.ncbi.nlm.nih.gov/23266469
Autor:
Jeong Ok Lee, Sun Hwa Park, Eung-Kyun Kim, Jin Hee Jung, Ji Man Park, Soo Kyung Lee, Ji Hae Kim, Pann-Ghill Suh, Jin Kyung An, Hyeon Soo Kim, Ga Young You
Publikováno v:
Journal of cellular physiology. 223(2)
Quercetin, an anti-oxidant flavonoid that is widely distributed in the plant kingdom, has been suggested to have chemopreventive effects on cancer cells, although the mechanism is not completely understood. In this study, we found that quercetin incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe09ebccdcf3819a4f863920a27e56f
https://pubmed.ncbi.nlm.nih.gov/20082303
https://pubmed.ncbi.nlm.nih.gov/20082303