Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gaëtane Macé"'
Publikováno v:
The Journal of Biological Chemistry
Previously, we have demonstrated that human oxidative DNA glycosylase NEIL1 excises photoactivated psoralen-induced monoadducts but not genuine interstrand cross-links (ICLs) in duplex DNA. It has been postulated that the repair of ICLs in mammalian
Autor:
Philippe Druet, E. Druet, Catherine Blanpied, Gilles Dietrich, Gaëtane Macé, Martial Jaume, Christophe Nguyen
Publikováno v:
Biochemical and Biophysical Research Communications. 280:1142-1147
We have previously reported the presence of IgG antibodies with a morphine-like activity in the serum of healthy individuals. The agonistic activity of IgG was dependent on their binding to the first and the third extracellular loops of the human mu
Publikováno v:
European Journal of Immunology. 29:997-1003
Although naturally occurring antibodies have been associated with numerous biological activities, their functional relevance is still a matter of debate. The presence of natural autoantibodies towards immune-related molecules such as cytokines and an
The Fanconi anemia pathway promotes DNA glycosylase-dependent excision of interstrand DNA crosslinks
Publikováno v:
Environmental and Molecular Mutagenesis.
Fanconi anemia (FA) is a recessive cancer prone syndrome featuring bone marrow failure and hypersensitivity to DNA interstrand crosslinks (ICLs) and, to a milder extension, to ionizing radiation and oxidative stress. Recently, we reported that human
Publikováno v:
Blood
Blood, American Society of Hematology, 2008, 111 (4), pp.1913-23. ⟨10.1182/blood-2007-07-099218⟩
Blood, American Society of Hematology, 2008, 111 (4), pp.1913-23. ⟨10.1182/blood-2007-07-099218⟩
Fanconi anemia (FA), an inherited syndrome that associates bone marrow failure, cancer predisposition, and genetic instability, is characterized by an overproduction of the myelosuppressive cytokine TNF-alpha through unknown mechanisms. We demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70fe7b032fc80c4f6e89fde52485aee
https://hal.archives-ouvertes.fr/hal-00282475
https://hal.archives-ouvertes.fr/hal-00282475
Publikováno v:
Nucleic Acids Research
Interstrand cross-link (ICL) is a covalent modification of both strands of DNA, which prevents DNA strand separation during transcription and replication. Upon photoactivation 8-methoxypsoralen (8-MOP+UVA) alkylates both strands of DNA duplex at the
Autor:
Filippo Rosselli, Jean-Hugues Guervilly, Massimo Bogliolo, Jean Antoine Dugas du Villard, Gaëtane Macé
Publikováno v:
Biochimie. 87(7)
Fanconi anemia (FA) is a recessive cancer prone syndrome featuring bone marrow failure and hypersensitivity to DNA crosslinks. Nine FA genes have been isolated so far. The biochemical function(s) of the FA proteins remain(s) poorly determined. Howeve
Autor:
Pierre Cavaillès, Sébastien Jacquet, Cécile Demur, P. Brousset, Gilles Dietrich, Lionel Stephan, Martial Jaume, Gaëtane Macé, Catherine Blanpied
Publikováno v:
Hepatology (Baltimore, Md.). 40(5)
Fas (CD95)-induced hepatocyte apoptosis and cytotoxic activity of neutrophils infiltrating the injured liver are two major events leading to hepatitis. Because it has been reported that opioids, via a direct interaction, sensitize splenocytes to Fas-
Publikováno v:
The Journal of biological chemistry. 274(29)
We have previously demonstrated that randomly selected healthy individuals express anti-human μ-opioid receptor antibodies which behave as agonist in vitro. In this study, we show that the activity of these antibodies was not affected by the deletio
Publikováno v:
Transplantation Proceedings. 30:3949