Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Gaëlle Tachon"'
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6344-6353 (2020)
Abstract Background Epigenetic inactivation of O6‐methylguanine‐methyltransferase (MGMT) gene by methylation of its promoter is predictive of Temozolomid (TMZ) response in glioblastoma (GBM). MGMT is located on chromosome 10q26 and the loss of ch
Externí odkaz:
https://doaj.org/article/379d796c9efa44ef9e38e62e58184717
Autor:
Gaëlle Tachon, Ulrich Cortes, Sophie Richard, Sébastien Martin, Serge Milin, Camille Evrard, Corinne Lamour, Lucie Karayan‐Tapon
Publikováno v:
Cancer Medicine, Vol 8, Iss 18, Pp 7556-7566 (2019)
Abstract Introduction ALK and ROS1 rearrangements are molecular targets of several tyrosine kinase inhibitors. RNA‐sequencing approaches are regarded as the new standard for fusion gene detection, representing an alternative to standard immunohisto
Externí odkaz:
https://doaj.org/article/cd5db8b4c49e4ba0a0b2cd5c7144f997
Autor:
Camille Evrard, Stéphane Messina, David Sefrioui, Éric Frouin, Marie-Luce Auriault, Romain Chautard, Aziz Zaanan, Marion Jaffrelot, Christelle De La Fouchardière, Thomas Aparicio, Romain Coriat, Julie Godet, Christine Silvain, Violaine Randrian, Jean-Christophe Sabourin, Rosine Guimbaud, Elodie Miquelestorena-Standley, Thierry Lecomte, Valérie Moulin, Lucie Karayan-Tapon, Gaëlle Tachon, David Tougeron
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4427 (2022)
Deficient mismatch repair system (dMMR)/microsatellite instability (MSI) is found in about 5% of metastatic colorectal cancers (mCRCs) with a major therapeutic impact for immune checkpoint inhibitor (ICI) use. We conducted a multicentre study includi
Externí odkaz:
https://doaj.org/article/0026cfb6268f42bcba3d36cf3204f151
Autor:
Gaëlle Tachon, Konstantin Masliantsev, Pierre Rivet, Amandine Desette, Serge Milin, Elise Gueret, Michel Wager, Lucie Karayan-Tapon, Pierre-Olivier Guichet
Publikováno v:
Cancers, Vol 13, Iss 23, p 5943 (2021)
The high expression of MEOX2 transcription factor is closely associated with poor overall survival in glioma. MEOX2 has recently been described as an interesting prognostic biomarker, especially for lower grade glioma. MEOX2 has never been studied in
Externí odkaz:
https://doaj.org/article/5b4d49ffb4484d5cb963230a23273b83
Autor:
Audelaure Junca, Gaëlle Tachon, Camille Evrard, Claire Villalva, Eric Frouin, Lucie Karayan-Tapon, David Tougeron
Publikováno v:
Cancers, Vol 12, Iss 6, p 1482 (2020)
Background: In most countries, participation in colorectal cancer (CRC) screening programs with the immunological fecal occult blood test (iFOBT) is low. Mutations of RAS and BRAF occur early in colorectal carcinogenesis and “liquid biopsy” allow
Externí odkaz:
https://doaj.org/article/d503d611e4c14174a3986b85ad567593
Publikováno v:
Cancers, Vol 11, Iss 10, p 1567 (2019)
Tumor DNA mismatch repair (MMR) deficiency testing is important to the identification of Lynch syndrome and decision making regarding adjuvant chemotherapy in stage II colorectal cancer (CRC) and has become an indispensable test in metastatic tumors
Externí odkaz:
https://doaj.org/article/c293c0b7ebb64aa7837684a27d9dfe82
Autor:
Gaëlle Tachon, C. Cheze-Le-Rest, R. Perdrisot, M. Berraho, L. Karayan-Tapon, Olena Tankyevych, A. Dambrain
Publikováno v:
Médecine Nucléaire. 45:13-18
Resume Objectif Le traitement des adenocarcinomes pulmonaires est conditionne par la presence de certaines anomalies genetiques. Certains parametres quantitatifs en TEP-TDM au 18FDG permettant, a l’echelle des voxels, de caracteriser la forme et la
Publikováno v:
Cancer Medicine, Vol 9, Iss 17, Pp 6344-6353 (2020)
Cancer Medicine
Cancer Medicine
Background Epigenetic inactivation of O6‐methylguanine‐methyltransferase (MGMT) gene by methylation of its promoter is predictive of Temozolomid (TMZ) response in glioblastoma (GBM). MGMT is located on chromosome 10q26 and the loss of chromosome
Autor:
Laurent Miguet, Florence Coulet, Celine Guien, Lucie Karayan-Tapon, Isabelle Soubeyran, Anne Cayre, Laurent Mauvieux, Etienne Muller, Karen Leroy, Alexandre Harlé, Christophe Béroud, Olfa Trabelsi Grati, Pierre Sujobert, Etienne Rouleau, Alexandra Lespagnol, Gaëlle Tachon, Florence Koeppel, Claude Preudhomme, David Salgado, Olivier Kosmider
Publikováno v:
European Journal of Cancer
European Journal of Cancer, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
European Journal of Cancer, Elsevier, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
European Journal of Cancer, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
European Journal of Cancer, Elsevier, 2021, 159, pp.1-15. ⟨10.1016/j.ejca.2021.08.047⟩
International audience; Background: The difficulty in interpreting somatic alterations is correlated with the increase in sequencing panel size. To correctly guide the clinical management of patients with cancer, there needs to be accurate classifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0543125e44b1e51aec427352cd59511
https://hal.science/hal-03408473
https://hal.science/hal-03408473
Autor:
Christos Petropoulos, Konstantin Masliantsev, Michel Wager, Julie Godet, Pierre Rivet, Lucie Karayan-Tapon, Serge Milin, Gaëlle Tachon, Pierre-Olivier Guichet
Publikováno v:
Modern Pathology. 32:774-786
Gliomas are the most common malignant primary tumors in the central nervous system and have variable predictive clinical courses. Glioblastoma, the most aggressive form of glioma, is a complex disease with unsatisfactory therapeutic solutions and a v