Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gaëlle Mariaule"'
Autor:
Gaëlle Mariaule, Philippe Belmont
Publikováno v:
Molecules, Vol 19, Iss 9, Pp 14366-14382 (2014)
In the early 2000s, the anticancer drug imatinib (Glivec®) appeared on the market, exhibiting a new mode of action by selective kinase inhibition. Consequently, kinases became a validated therapeutic target, paving the way for further developments.
Externí odkaz:
https://doaj.org/article/8b59261403354858befa7793447f714f
Autor:
Alexis Bontemps, Philippe Belmont, Philippe Helissey, Véronique Michelet, Stéphanie Desbène-Finck, Sylviane Giorgi-Renault, Gaëlle Mariaule
Publikováno v:
Synthesis. 48:2178-2190
A silver trifluoromethanesulfonate catalyzed efficient access to the indolylpyranoquinoline scaffold is reported. Starting from 2-alkynylquinoline-3-carbaldehyde units with various substitution patterns on the quinoline and alkynyl parts, the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea8645e2b9c6732d37d07f0f122677f
https://doi.org/10.1055/s-0035-1562234
https://doi.org/10.1055/s-0035-1562234
Autor:
Anthony Mittermaier, Igor Huskić, Stéphane De Cesco, Karine Auclair, Francesco Airaghi, Sylvain Rocheleau, Jerry Kurian, Nicolas Moitessier, Gaëlle Mariaule, Paolo Schiavini
Publikováno v:
Journal of Medicinal Chemistry. 59:4221-4234
Bicyclic chiral scaffolds are privileged motifs in medicinal chemistry. Over the years, we have reported covalent bicyclic prolyl oligopeptidase inhibitors that were highly selective for POP over a number of homologous proteins. Herein, we wish to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed6c9397484713b61e4c2579832a7c6
https://doi.org/10.1021/acs.jmedchem.5b01296
https://doi.org/10.1021/acs.jmedchem.5b01296
Autor:
Véronique Michelet, Patrick Y. Toullec, Gaëlle Mariaule, Gregory John Robert Newsome, Philippe Belmont
Publikováno v:
Organic Letters. 16:4570-4573
A Ag-catalyzed versatile and efficient access to 1H,1-arylisochromenes is reported. Starting from ortho-alkynylbenzaldehydes bearing various substitution patterns on the benzaldehyde and alkynyl units, the use of silver triflate (10 mol %) allowed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051631f28439665bcaaae6378aeae8bc
https://doi.org/10.1021/ol5021256
https://doi.org/10.1021/ol5021256
Autor:
Gaëlle Mariaule, Philippe Helissey, Véronique Michelet, Stéphanie Desbène-Finck, Philippe Belmont, Sylviane Giorgi-Renault, Alexis Bontemps
Publikováno v:
ChemInform. 47
A silver trifluoromethanesulfonate catalyzed efficient access to the indolylpyranoquinoline scaffold is reported. Starting from 2-alkynylquinoline-3-carbaldehyde units with various substitution patterns on the quinoline and alkynyl parts, the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f5066423cbbeb06d5d49fca2fd484d
https://doi.org/10.1002/chin.201649157
https://doi.org/10.1002/chin.201649157
Autor:
Patrick Y. Toullec, Véronique Michelet, Gregory John Robert Newsome, Philippe Belmont, Gaëlle Mariaule
Publikováno v:
ChemInform. 46
An unprecedented Ag(I)-catalyzed hydroarylation/cycloisomerization domino process of ortho-alkynyl benzaldehydes and electron rich arenes is developed to give isochromene derivatives.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a36af0b69a554b6f79f89b2a13a7aec5
https://doi.org/10.1002/chin.201510179
https://doi.org/10.1002/chin.201510179
Autor:
Philippe Belmont, Véronique Michelet, Alexis Bontemps, Gaëlle Mariaule, Stéphanie Desbène-Finck, Philippe Helissey, Sylviane Giorgi-Renault
Publikováno v:
Synthesis. 48:e5-e5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11b91db56783553bc29762be551f3ab9
https://doi.org/10.1055/s-0035-1562549
https://doi.org/10.1055/s-0035-1562549
Publikováno v:
Organic & Biomolecular Chemistry; 9/7/2023, Vol. 21 Issue 33, p6629-6635, 7p
Publikováno v:
Organic & Biomolecular Chemistry; 9/7/2023, Vol. 21 Issue 33, p6730-6737, 8p
Autor:
Mariaule, Gaëlle1,2 gaelle.mariaule@curie.fr, Belmont, Philippe1,2 philippe.belmont@parisdescartes.fr
Publikováno v:
Molecules. Sep2014, Vol. 19 Issue 9, p14366-14382. 17p.