Cell-assembled extracellular matrix (CAM): a human biopaper for the biofabrication of pre-vascularized tissues able to connect to the host circulation

Autor: Sylvain Catros, C. Handschin, Laure Magnan, Hugo Oliveira, Marie-Laure Stachowicz, Nathalie Dusserre, Gaëlle Labrunie, Jean-Christophe Fricain, Chantal Medina, Nicolas L'Heureux

Publikováno v: Biofabrication. 14(1)

When considering regenerative approaches, the efficient creation of a functional vasculature, that can support the metabolic needs of bioengineered tissues, is essential for their survival after implantation. However, it is widely recognized that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf4339f25528f081cdca4401a2edc79e
https://pubmed.ncbi.nlm.nih.gov/34695012

In vivo remodeling of human cell-assembled extracellular matrix yarns

Autor: Laure, Magnan, Fabien, Kawecki, Gaëlle, Labrunie, Maude, Gluais, Julien, Izotte, Sébastien, Marais, Marie-Pierre, Foulc, Mickaël, Lafourcade, Nicolas, L'Heureux

Publikováno v: Biomaterials. 273

Cell-assembled extracellular matrix (CAM) has been used to produce vascular grafts. While these completely biological vascular grafts performed well in clinical trials, the in vivo remodeling and inflammatory response of this truly "bio" material has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::927da3a4b73b97abf7f5ff3357e38946
https://pubmed.ncbi.nlm.nih.gov/33894404

Characterization of a Cell-Assembled extracellular Matrix and the effect of the devitalization process

Autor: Gaëlle Labrunie, Marc Bonneu, Nicolas L'Heureux, Sabrina Lacomme, Sylvie Rey, Sébastien Marais, Etienne Gontier, Laure Magnan, Nathalie Dusserre

Publikováno v: Acta Biomaterialia
Acta Biomaterialia, Elsevier, 2018, 82, pp.56-67. ⟨10.1016/j.actbio.2018.10.006⟩
Acta Biomaterialia, 2018, 82, pp.56-67. ⟨10.1016/j.actbio.2018.10.006⟩

International audience; We have previously shown that the Cell-Assembled extracellular Matrix (CAM) synthesized by normal, human, skin fibroblasts in vitro can be assembled in a completely biological vascular graft that was successfully tested in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b204fb0894d84eaf9b9fa221f3ff495b
https://www.hal.inserm.fr/inserm-02870985

p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells

Autor: J-M Pasquet, P Bensadoun, Evelyne Ségal-Bendirdjian, A. Trocoli, Josy Reiffers, Mario P. Tschan, Daniel Brigger, Gaëlle Labrunie, Faten Merhi, Elodie Richard, S. Souquère, Mojgan Djavaheri-Mergny, G. Pierron, Anna M. Schläfli, Pierre Soubeyran

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, Nature Publishing Group, 2014, 21 (12), pp.1852-1861. ⟨10.1038/cdd.2014.102⟩
CELL DEATH AND DIFFERENTIATION
Cell Death and Differentiation, 2014, 21 (12), pp.1852-1861. ⟨10.1038/cdd.2014.102⟩

International audience; The p62/SQSTM1 adapter protein has an important role in the regulation of several key signaling pathways and helps transport ubiquitinated proteins to the autophagosomes and proteasome for degradation. Here, we investigate the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf2a5b5e29005e7728e31ad268b9033
https://www.hal.inserm.fr/inserm-02627063