Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Gaëlle Charier"'
1
The Tudor Tandem of 53BP1
Autor: Bernard Gilquin, Eric Quéméneur, Sophie Zinn-Justin, Isabelle Callebaut, Gaëlle Charier, Raphael Guerois, Béatrice Alpha-Bazin, Joël Couprie, Vincent Meyer
Publikováno v: Structure. 12:1551-1562
53BP1 is a key transducer of the DNA damage checkpoint signal, which is required for phosphorylation of a subset of ATM substrates and p53 accumulation. After cell irradiation, the 53BP1 N-terminal region is phosphorylated. Its two C-terminal BRCT mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2aa5584c4323e68dedeb9c1c1844aaa
https://doi.org/10.1016/j.str.2004.06.014
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2
The checkpoint Saccharomyces cerevisiae Rad9 protein contains a tandem tudor domain that recognizes DNA
Autor: Béatrice Alpha-Bazin, Simona Miron, Nathalie Lancelot, Gaëlle Charier, Bernard Gilquin, Constantin T. Craescu, Isabelle Duband-Goulet, Joël Couprie, Marie-Claude Marsolier-Kergoat, Eric Quéméneur, Sophie Zinn-Justin, Isabelle Callebaut, Jean-Baptiste Charbonnier, Emilie Ma, Virginie Ropars
Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2007, pp.1-15. ⟨10.1093/nar/gkm607⟩
Nucleic Acids Research, Oxford University Press, 2007, pp.5898-5912
Nucleic Acids Research, 2007, 35 (17), pp.5898-912. ⟨10.1093/nar/gkm607⟩
Nucleic Acids Research, Oxford University Press, 2007, 35 (17), pp.5898-912. ⟨10.1093/nar/gkm607⟩
International audience; DNA damage checkpoints are signal transduction pathways that are activated after genotoxic insults to protect genomic integrity. At the site of DNA damage, ‘mediator' proteins are in charge of recruiting ‘signal transducer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea096c6ec373ab14cd258112a6577530
https://hal.archives-ouvertes.fr/hal-00173232
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3
Boundaries and physical characterization of a new domain shared between mammalian 53BP1 and yeast Rad9 checkpoint proteins
Autor: Eric Quéméneur, Sophie Zinn-Justin, Gaëlle Charier, Frédéric Bérenguer, Nathalie Nozerand, Alain Lorphelin, Bernard Gilquin, Joël Couprie, Béatrice Alpha-Bazin, Charles Marchetti
Publikováno v: Protein science : a publication of the Protein Society. 14(7)
Eukaryotic cells have evolved DNA damage checkpoints in response to genome damage. They delay the cell cycle and activate repair mechanisms. The kinases at the heart of these pathways and the accessory proteins, which localize to DNA lesions and regu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47edd9d44e783a619481be5e037e74d
https://pubmed.ncbi.nlm.nih.gov/15987907
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4
The Tudor tandem of 53BP1: a new structural motif involved in DNA and RG-rich peptide binding
Autor: Gaëlle, Charier, Joël, Couprie, Béatrice, Alpha-Bazin, Vincent, Meyer, Eric, Quéméneur, Raphaël, Guérois, Isabelle, Callebaut, Bernard, Gilquin, Sophie, Zinn-Justin
Publikováno v: Structure (London, England : 1993). 12(9)
53BP1 is a key transducer of the DNA damage checkpoint signal, which is required for phosphorylation of a subset of ATM substrates and p53 accumulation. After cell irradiation, the 53BP1 N-terminal region is phosphorylated. Its two C-terminal BRCT mo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4dd8d48f4398f79bcfde840220fe705f
https://pubmed.ncbi.nlm.nih.gov/15341721
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