Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Gaëlle, Tilly"'
Autor:
Nicolas Sailliet, Hoa-Le Mai, Amandine Dupuy, Gaëlle Tilly, Cynthia Fourgeux, Martin Braud, Magali Giral, Jean-Michel Robert, Nicolas Degauque, Richard Danger, Jeremie Poschmann, Sophie Brouard
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHuman Granzyme B (GZMB) regulatory B cells (Bregs) have suppressive properties on CD4+ effector T cells by a mechanism partially dependent on GZMB. Moreover, these cells may be easily induced in vitro making them interesting for cell ther
Externí odkaz:
https://doaj.org/article/fd8ac4765aaa4e34853bc71dad38a34f
Autor:
Gaëlle Tilly, Marion Cadoux, Alexandra Garcia, Jérémy Morille, Sandrine Wiertlewski, Claire Pecqueur, Sophie Brouard, David Laplaud, Nicolas Degauque
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Background and ObjectivesInhibition of de novo pyrimidine synthesis in proliferating T and B lymphocytes by teriflunomide, a pharmacological inhibitor of dihydroorotate dehydrogenase (DHODH), has been shown to be an effective therapy to treat patient
Externí odkaz:
https://doaj.org/article/a07d9ea562304e78906881830d7bc40a
Autor:
Tra-My Doan Ngoc, Gaëlle Tilly, Richard Danger, Orianne Bonizec, Christophe Masset, Pierrick Guérif, Sarah Bruneau, Alexandre Glemain, Jean Harb, Marion Cadoux, Anaïs Vivet, Hoa Le Mai, Alexandra Garcia, David Laplaud, Roland Liblau, Magali Giral, Stéphanie Blandin, Magalie Feyeux, Laurence Dubreuil, Claire Pecqueur, Matthew Cyr, Weiming Ni, Sophie Brouard, Nicolas Degauque
Publikováno v:
Journal of the American Society of Nephrology. 33:2211-2231
Autor:
Annick Le Dur, Thanh Lan Laï, Marie-George Stinnakre, Aude Laisné, Nathalie Chenais, Sabine Rakotobe, Bruno Passet, Fabienne Reine, Solange Soulier, Laetitia Herzog, Gaëlle Tilly, Human Rézaei, Vincent Béringue, Jean-Luc Vilotte, Hubert Laude
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
PrPC protein plays a key role in prion transmission across species. Here, the authors compare transmission of a representative scrapie isolate to transgenic mice expressing variable levels of the same Prnp allele as the donor sheep, and find divergen
Externí odkaz:
https://doaj.org/article/010dfaabcfa2495381f0b8a4b4e912ee
Autor:
Gaëlle Tilly, Tra-My Doan-Ngoc, Michelle Yap, Aurélie Caristan, Lola Jacquemont, Richard Danger, Marion Cadoux, Sarah Bruneau, Magali Giral, Pierrick Guerif, Bryan Nicol, Alexandra Garcia, David-Axel Laplaud, Sophie Brouard, Claire Pecqueur Hellman, Nicolas Degauque
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The involvement of TEMRA CD8 is evident in a large array of immunological conditions ranging from auto- to allo-immunity. Nevertheless, the factors leading to their accumulation and activation remain ill-defined and, efficient therapeutics to control
Externí odkaz:
https://doaj.org/article/3e5ec2a0a6b9412c97445fa95fb1fd17
Autor:
Yohann Foucher, Pierrick Guerif, Nicolas Degauque, Sophie Brouard, Richard Danger, Florent Delbos, Gaëlle Tilly, Lola Jacquemont, Magali Giral, Bernard Martinet, Michelle Yap, Tra-My Doan-Ngoc
Publikováno v:
Journal of the American Society of Nephrology. 31:876-891
Background Identifying biomarkers to predict kidney transplant failure and to define new therapeutic targets requires more comprehensive understanding of the immune response to chronic allogeneic stimulation. Methods We investigated the frequency and
Autor:
Aurélie Moreau, Céline Vandamme, Mercedes Segovia, Marie Devaux, Mickaël Guilbaud, Gaëlle Tilly, Nicolas Jaulin, Johanne Le Duff, Yan Cherel, Jack-Yves Deschamps, Ignacio Anegon, Philippe Moullier, Maria Cristina Cuturi, Oumeya Adjali
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Preventing untoward immune responses against a specific antigen is a major challenge in different clinical settings such as gene therapy, transplantation, or autoimmunity. Following intramuscular delivery of recombinant adeno-associated virus (rAAV)-
Externí odkaz:
https://doaj.org/article/6a2fa6a406d94ab892a87a5739bb4b38
Autor:
Marcelo Hill, Ala-Eddine Deghmane, Mercedes Segovia, Maria Leticia Zarantonelli, Gaëlle Tilly, Philippe Blancou, Gaëlle Bériou, Régis Josien, Ignacio Anegon, Eva Hong, Corinne Ruckly, Aude Antignac, Meriem El Ghachi, Ivo Gomperts Boneca, Muhamed-Kheir Taha, Maria Cristina Cuturi
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e23995 (2011)
Neisseria meningitidis is a human pathogen responsible for life-threatening inflammatory diseases. Meningococcal penicillin-binding proteins (PBPs) and particularly PBP2 are involved in bacterial resistance to β-lactams. Here we describe a novel fun
Externí odkaz:
https://doaj.org/article/61e725d987f74644a96064e4514e5ca7
Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy.
Autor:
Vincent Béringue, Anna Bencsik, Annick Le Dur, Fabienne Reine, Thanh Lan Laï, Nathalie Chenais, Gaëlle Tilly, Anne-Gaëlle Biacabé, Thierry Baron, Jean-Luc Vilotte, Hubert Laude
Publikováno v:
PLoS Pathogens, Vol 2, Iss 10, p e112 (2006)
To date, bovine spongiform encephalopathy (BSE) and its human counterpart, variant Creutzfeldt-Jakob disease, have been associated with a single prion strain. This strain is characterised by a unique and remarkably stable biochemical profile of abnor
Externí odkaz:
https://doaj.org/article/5eb332d89e1a4a798284ef530a20c8ff
Autor:
Lola, Jacquemont, Gaëlle, Tilly, Michelle, Yap, Tra-My, Doan-Ngoc, Richard, Danger, Pierrick, Guérif, Florent, Delbos, Bernard, Martinet, Magali, Giral, Yohann, Foucher, Sophie, Brouard, Nicolas, Degauque
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Identifying biomarkers to predict kidney transplant failure and to define new therapeutic targets requires more comprehensive understanding of the immune response to chronic allogeneic stimulation. METHODS: We investigated the frequency a