Zobrazeno 1 - 10
of 64
pro vyhledávání: '"GUSTAVO YANNARELLI"'
Autor:
Ricardo Malvicini, Diego Santa-Cruz, Anna Maria Tolomeo, Maurizio Muraca, Gustavo Yannarelli, Natalia Pacienza
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291589 (2023)
In the last few years, extracellular vesicles (EVs) have become of great interest due to their potential as biomarkers, drug delivery systems, and, in particular, therapeutic agents. However, there is no consensus on which is the best way to isolate
Externí odkaz:
https://doaj.org/article/bd4f2f6133864fb08a883baeec6cc035
Autor:
Andrea Papait, Antonietta Rosa Silini, Maria Gazouli, Ricardo Malvicini, Maurizio Muraca, Lorraine O’Driscoll, Natalia Pacienza, Wei Seong Toh, Gustavo Yannarelli, Peter Ponsaerts, Ornella Parolini, Günther Eissner, Michela Pozzobon, Sai Kiang Lim, Bernd Giebel
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Perinatal tissues, mainly the placenta and umbilical cord, contain a variety of different somatic stem and progenitor cell types, including those of the hematopoietic system, multipotent mesenchymal stromal cells (MSCs), epithelial cells and amnion e
Externí odkaz:
https://doaj.org/article/9cc59fafb0fc4698b80df76a66adc772
Autor:
María Cecilia Sanmartin, Francisco Raúl Borzone, María Belén Giorello, Gustavo Yannarelli, Norma Alejandra Chasseing
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Cancer is the second leading cause of death worldwide, with 10.0 million cancer deaths in 2020. Despite advances in targeted therapies, some pharmacological drawbacks associated with anticancer chemo and immunotherapeutic agents include high toxiciti
Externí odkaz:
https://doaj.org/article/2db53e3619dd42eea65cc683bf39e251
Autor:
Natalia Pacienza, Ryang Hwa Lee, Eun-Hye Bae, Dong-ki Kim, Qisong Liu, Darwin J. Prockop, Gustavo Yannarelli
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 67-76 (2019)
Extracellular vesicles (EVs) play key roles in cell biology and may provide new clinical diagnostics and therapies. However, it has proven difficult to develop protocols for their purification and characterization. One of the major barriers in the fi
Externí odkaz:
https://doaj.org/article/edf9fc30177047ae834b933eb1960fa5
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Early detection of cancer has great clinical importance and potentially improves cure, survival rate and treatment outcome. RNA editing technology can be used as targeted and precise molecular scissors to cut and replace disease-causing genes with he
Externí odkaz:
https://doaj.org/article/a0bc2d3af37a4d10b943077117848f11
Autor:
Anna Maria Tolomeo, Assunta Fabozzo, Ricardo Malvicini, Giada De Lazzari, Paola Bisaccia, Gianluca Gaburro, Diletta Arcidiacono, Denni Notarangelo, Federico Caicci, Fabio Zanella, Massimo Marchesan, Gustavo Yannarelli, Gianfranco Santovito, Maurizio Muraca, Gino Gerosa
Publikováno v:
Antioxidants, Vol 11, Iss 3, p 476 (2022)
Insufficient supply of cardiac grafts represents a severe obstacle in heart transplantation. Donation after circulatory death (DCD), in addition to conventional donation after brain death, is one promising option to overcome the organ shortage. Howev
Externí odkaz:
https://doaj.org/article/5fa89215e2ca49e1934c85159e5a0b42
Autor:
Diego Santa-Cruz, Natalia Pacienza, Carla Zilli, Eduardo Pagano, Karina Balestrasse, Gustavo Yannarelli
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 549-557 (2017)
Heme oxygenase-1 (HO-1) plays a protective role against oxidative stress in plants. The mechanisms regulating its expression, however, remain unclear. Here we studied the methylation state of a GC rich HO-1 promoter region and the expression of sever
Externí odkaz:
https://doaj.org/article/391617ec54fd403a91358f32da7504ae
Autor:
Natalia Pacienza, Diego Santa-Cruz, Ricardo Malvicini, Oscar Robledo, Gastón Lemus-Larralde, Alejandro Bertolotti, Martín Marcos, Gustavo Yannarelli
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Lung transplantation is a lifesaving therapy for people living with severe, life-threatening lung disease. The high mortality rate among patients awaiting transplantation is mainly due to the low percentage of lungs that are deemed acceptable for imp
Externí odkaz:
https://doaj.org/article/3fe9cd329040469bbe73f47d9e66badb
Autor:
Gustavo Yannarelli, Natalia Pacienza, Sonia Montanari, Diego Santa-Cruz, Sowmya Viswanathan, Armand Keating
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189131 (2017)
Mesenchymal stem/stromal cells (MSCs) are in numerous cell therapy clinical trials, including for injured myocardium. Acquisition of cardiomyocyte characteristics by MSCs may improve cardiac regeneration but the mechanisms regulating this process are
Externí odkaz:
https://doaj.org/article/ba43487a51c24e8c9bda1f92315f75b1
Autor:
Gustavo Yannarelli Ph.D., Victor Dayan, Natalia Pacienza, Chyan-Jang Lee, Jeffrey Medin, Armand Keating
Publikováno v:
Cell Transplantation, Vol 22 (2013)
We were interested in evaluating the ability of the mesenchymal stromal cell (MSC) population, human umbilical cord perivascular cells (HUCPVCs), to undergo cardiomyocyte reprogramming in an established coculture system with rat embryonic cardiomyocy
Externí odkaz:
https://doaj.org/article/2880ee48086b4dfe8581ada322c04296