Výsledky vyhledávání - "GUIDOTTI, M. T."

Akademický článek

L-368,899, a potent orally active oxytocin antagonist for potential use in preterm labor.

Publikováno v: Drug Development Research; Nov1993, Vol. 30 Issue 3, p129-142, 14p

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Periodical

Nonpeptide oxytocin antagonists: potent, orally bioavailable analogs of L-371,257 containing a 1-R-(pyridyl)ethyl ether terminus

Autor: Kuo, M. S., Bock, M. G., Freidinger, R. M., Guidotti, M. T., Lis, E. V., Pawluczyk, J. M., Perlow, D. S., Pettibone, D. J., Quigley, A. G., Reiss, D. R.

Publikováno v: Bioorganic & Medicinal Chemistry Letters; 1998, Vol. 8 Issue: 21 p3081-3086, 6p

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Periodical

Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines

Autor: Bell, I. M., Erb, J. M., Freidinger, R. M., Gallicchio, S. N., Guare, J. P., Guidotti, M. T., Halpin, R. A., Hobbs, D. W., Homnick, C. F., Kuo, M. S., Lis, E. V., Mathre, D. J., Michelson, S. R., Pawluczyk, J. M., Pettibone, D. J., Reiss, D. R., Vickers, S., Williams, P. D., Woyden, C. J.

Publikováno v: Journal of Medicinal Chemistry; June 4, 1998, Vol. 41 Issue: 12 p2146-2163, 18p

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Akademický článek

ChemInform Abstract: 1-(1-(4-((N-Acetyl-4-piperidinyl)oxy)-2-methoxybenzoyl)piperidin-4-yl)- 4H-3,1-benzoxazin-2(1H)-one (L-371,257): A New, Orally Bioavailable, Non-Peptide Oxytocin Antagonist.

Autor: WILLIAMS, P. D., CLINESCHMIDT, B. V., ERB, J. M., FREIDINGER, R. M., GUIDOTTI, M. T., LIS, E. V., PAWLUCZYK, J. M., PETTIBONE, D. J., REISS, D. R., VEBER, D. F., WOYDEN, C. J.

Publikováno v: ChemInform; Mar1996, Vol. 27 Issue 11, pno-no, 1p

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Akademický článek

Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency.

Autor: Williams PD; Department of Medicinal Chemistry, Merck Research Laboratories, West Point, PA 19486, USA., Bock MG, Evans BE, Freidinger RM, Gallicchio SN, Guidotti MT, Jacobson MA, Kuo MS, Levy MR, Lis EV, Michelson SR, Pawluczyk JM, Perlow DS, Pettibone DJ, Quigley AG, Reiss DR, Salvatore C, Stauffer KJ, Woyden CJ

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 1999 May 03; Vol. 9 (9), pp. 1311-6.

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Akademický článek

Cloning and expression of the rhesus monkey oxytocin receptor.

Autor: Salvatore CA; Merck Research Laboratories, Department of Pharmacology, West Point, PA 19486, USA., Woyden CJ, Guidotti MT, Pettibone DJ, Jacobson MA

Publikováno v: Journal of receptor and signal transduction research [J Recept Signal Transduct Res] 1998 Jan; Vol. 18 (1), pp. 15-24.

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Akademický článek

1-(1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4- yl)-4H-3,1-benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist.

Autor: Williams PD; Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA., Clineschmidt BV, Erb JM, Freidinger RM, Guidotti MT, Lis EV, Pawluczyk JM, Pettibone DJ, Reiss DR, Veber DF, et. al.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1995 Nov 10; Vol. 38 (23), pp. 4634-6.

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