Zobrazeno 1 - 10
of 13
pro vyhledávání: '"GUANGXIN MIAO"'
Publikováno v:
Molecules, Vol 24, Iss 13, p 2394 (2019)
To explore the molecular mechanisms of BAY R3401, four types of novel photoaffinity probes bearing different secondary tags were synthesized. Their potency for glycogenolysis was evaluated in primary human liver HL-7702 cells and HepG2 cells. Probe 2
Externí odkaz:
https://doaj.org/article/94974a8fca7847e79c6ae1d3376b8a0c
Publikováno v:
Molecules, Vol 24, Iss 4, p 798 (2019)
A procedure to measure the serum concentration of glycogen phosphorylase during acute myocardial infarction is presented. This method was based on the synthesis of photoaffinity probes, and used the semiquantitative protein electrophoretic mobility s
Externí odkaz:
https://doaj.org/article/043dfaa0f518438b826b0331cc282e04
Autor:
Hongwei Wei, Jinhua Chang, Pei Liu, Zhongsi Li, Guangxin Miao, Xigang Liu, Cuizhe Liu, Xiangrong Zhang
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 55
Rhubarb is commonly used as a cathartic in Asian countries. However, researchers have devotedextensive concerns to the quality control and safety of rhubarb and traditional Chinese preparations composed of rhubarb due to the instable purgative effect
Externí odkaz:
https://doaj.org/article/ca693ad3fa7346a6b6d56e626e7f81c4
Autor:
Pei Liu, Liyan Liu, Xigang Liu, Li Zhongsi, Jinhua Chang, Xiaodong Gu, Qiang Fu, Guangxin Miao, Cuizhe Liu, Lin Zhang, Xue Hefei
Publikováno v:
Journal of Drug Delivery Science and Technology. 43:415-422
Objective This study aimed to compare pharmacokinetics of rhubarb total free anthraquinones (AQs) oral colon-specific delivery granules (RTFA-OCDD-GN) and rhubarb after oral administration to evaluate the colonic-target releasing characteristic of RT
Autor:
Cuizhe Liu, Liyan Liu, Guangxin Miao, Hongwei Wei, Li Zhongsi, Xiangrong Zhang, Jinhua Chang, Pei Liu, Xigang Liu
Publikováno v:
Experimental and Therapeutic Medicine
Rhubarb is commonly used to treat constipation in China and anthraquinones (AQs) are the active components present in rhubarb. However, an increasing number of studies have reported that AQs induce nephrotoxicity. In the present study, rhubarb total
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(14)
A small set of indole-2-carboxamide derivatives identified from a high-throughput screening campaign has been described as a novel, potent, and glucose-sensitive inhibitors of glycogen phosphorylase a (GPa). Among this series of compounds, compound 2
Publikováno v:
Molecules
Volume 24
Issue 13
Molecules, Vol 24, Iss 13, p 2394 (2019)
Volume 24
Issue 13
Molecules, Vol 24, Iss 13, p 2394 (2019)
To explore the molecular mechanisms of BAY R3401, four types of novel photoaffinity probes bearing different secondary tags were synthesized. Their potency for glycogenolysis was evaluated in primary human liver HL-7702 cells and HepG2 cells. Probe 2
Publikováno v:
Scientific Reports
PSN-357, an effective glycogen phosphorylase (GP) inhibitor for the treatment for type 2 diabetics, is hampered in its clinical use by the poor selectivity between the GP isoforms in liver and in skeletal muscle. In this study, by the introduction of
Autor:
PEI LIU, HONGWEI WEI, JINHUA CHANG, GUANGXIN MIAO, XIGANG LIU, ZHONGSI LI, LIYAN LIU, XIANGRONG ZHANG, CUIZHE LIU
Publikováno v:
Experimental & Therapeutic Medicine; Oct2017, Vol. 14 Issue 4, p3589-3601, 13p
Publikováno v:
Neural Regeneration Research
Previous experimental studies have shown that cerebral infarction can be effectively reduced following treatment with scutellaria baicalensis stem-leaf total flavonoid (SSTF). However, the mechanism of action of SSTF as a preventive drug to treat cer