Zobrazeno 1 - 10
of 522
pro vyhledávání: '"GTEx"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background African cattle represent a unique resource of genetic diversity in response to adaptation to numerous environmental challenges. Characterising the genetic landscape of indigenous African cattle and identifying genomic regions and
Externí odkaz:
https://doaj.org/article/e86ece856d8448eeac98d17040f9b61b
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Housekeeping protein-coding genes are stably expressed genes in cells and tissues that are thought to be engaged in fundamental cellular biological functions. They are often utilized as normalization references in molecular biology research
Externí odkaz:
https://doaj.org/article/1a29d79cdde645c99f0fcc3a239932cc
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
IntroductionThe tumor microenvironment and IRGs are highly correlated with tumor occurrence, progression, and prognosis. However, their roles in grade II and III gliomas, termed LGGs in this study, remain to be fully elucidated. Our research aims to
Externí odkaz:
https://doaj.org/article/2f5f5a58c4d3455da480728d20e3c7df
Publikováno v:
Molecular and Cellular Probes, Vol 76, Iss , Pp 101971- (2024)
Objective: This study aimed to conclude the effect and mechanism of ZIC2 on immune infiltration in lung adenocarcinoma (LUAD). Methods: Expression of ZIC2 in several kinds of normal tissues of TCGA data was analyzed and its correlation with the basel
Externí odkaz:
https://doaj.org/article/3b85c54cb4504acc97275c432cb01ff0
Autor:
Michael Svensson, Alen Lovric, Torbjörn Åkerfeldt, David Hellsten, Tara Haas, Thomas Gustafsson, Eric Rullman
Publikováno v:
Physiological Reports, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Exercise has different effects on different tissues in the body, the sum of which may determine the response to exercise and the health benefits. In the present study, we aimed to investigate whether physical training regulates transcription
Externí odkaz:
https://doaj.org/article/64f0ff24627c4717a95d96aba1d65b3b
Autor:
Bo Sun, Liang Chen
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-26 (2023)
Abstract Background Nonsense-mediated mRNA decay (NMD) was originally conceived as an mRNA surveillance mechanism to prevent the production of potentially deleterious truncated proteins. Research also shows NMD is an important post-transcriptional ge
Externí odkaz:
https://doaj.org/article/971068b1c741483d87706ac94d8149a4
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that affects over 50 million elderly individuals worldwide. Although the pathogenesis of AD is not fully understood, based on current research, researchers are able to identify po
Externí odkaz:
https://doaj.org/article/addd213c8d7148d4a9424fc8ad4fcf50
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21283- (2023)
Human endogenous retroviruses (HERVs) are remnants of ancient retroviral infections in the human genome. RNA expression of individual HERVs has frequently been observed in various pathologic conditions, but some activity can also be seen in healthy i
Externí odkaz:
https://doaj.org/article/07c3de5a70664925b71904380378fdf5
Publikováno v:
HGG Advances, Vol 4, Iss 4, Pp 100223- (2023)
Summary: Accurate imputation of tissue-specific gene expression can be a powerful tool for understanding the biological mechanisms underlying human complex traits. Existing imputation methods can be grouped into two categories according to the types
Externí odkaz:
https://doaj.org/article/e34342f724d1456b971fb801483ef01d
Autor:
Jibril B. Hirbo, Francesca Pasutto, Eric R. Gamazon, Patrick Evans, Priyanka Pawar, Daniel Berner, Julia Sealock, Ran Tao, Peter S. Straub, Anuar I. Konkashbaev, Max A. Breyer, Ursula Schlötzer-Schrehardt, André Reis, Milam A. Brantley, Chiea C. Khor, Karen M. Joos, Nancy J. Cox
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Exfoliation syndrome (XFS) is an age-related systemic disorder characterized by excessive production and progressive accumulation of abnormal extracellular material, with pathognomonic ocular manifestations. It is the most common
Externí odkaz:
https://doaj.org/article/82d3f177781d42b589d0669591c932ac