Zobrazeno 1 - 10
of 296
pro vyhledávání: '"GT Tucker"'
Autor:
GT Tucker
Publikováno v:
Alimentary Pharmacology & Therapeutics. 8:33-38
An understanding of the role of human cytochromes (CYPs) P450 in the metabolism of proton pump inhibitors (PPIs) is important in assuring the safety of these drugs. Species' differences in the metabolism of PPIs tend to overestimate the risk of some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749358ec41743d1b96e9abbc9982e07f
https://doi.org/10.1111/j.1365-2036.1994.tb00233.x
https://doi.org/10.1111/j.1365-2036.1994.tb00233.x
Publikováno v:
British Journal of Clinical Pharmacology. 33:521-523
Paroxetine is a selective serotonin reuptake inhibitor possessing anti-depressant activity. Demethylenation of the methylenedioxy phenyl group is the initial step in its metabolism, the liberated carbon appearing in vitro as formate. A radioassay inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::992edaeb497b89071f848990d691e429
https://doi.org/10.1111/j.1365-2125.1992.tb04082.x
https://doi.org/10.1111/j.1365-2125.1992.tb04082.x
The frequency distributions of the 0-8 h urinary metabolic ratios of debrisoquine and mephenytoin were measured in 111 healthy, unrelated Sinhalese resident in Sri Lanka. Blood samples were taken from 77 of these subjects for CYP2D6 genotyping. Bimod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d4ee13fdaacd709826198a6e7d83a7
https://europepmc.org/articles/PMC1364882/
https://europepmc.org/articles/PMC1364882/
Publikováno v:
British Journal of Clinical Pharmacology. 10:237-244
1 The cardiac effects of disopyramide (D) and lignocaine (L) were measured and compared in normal volunteers (D n=4; L n=3) following the establishment of a series of three steady-state drug plasma concentrations spanning the therapeutic range (1.5-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbd74e7e4d72f827522a11131247884
https://doi.org/10.1111/j.1365-2125.1980.tb01750.x
https://doi.org/10.1111/j.1365-2125.1980.tb01750.x
Publikováno v:
British journal of clinical pharmacology. 24(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33d3746034a6edaa5f94c53acc36bf4
https://pubmed.ncbi.nlm.nih.gov/3620282
https://pubmed.ncbi.nlm.nih.gov/3620282
Autor:
GT Tucker
Publikováno v:
British journal of clinical pharmacology. 12(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e3700048c4115a4bad1b4c474127b5
https://pubmed.ncbi.nlm.nih.gov/7041933
https://pubmed.ncbi.nlm.nih.gov/7041933
Publikováno v:
British Journal of Clinical Pharmacology. 8:398P-399P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b6cc937c64e7640fab72b722a811cf
https://doi.org/10.1111/j.1365-2125.1979.tb04745.x
https://doi.org/10.1111/j.1365-2125.1979.tb04745.x
Autor:
Mather LE; Anaesthesia, The University of Sydney, Sydney, New South Wales, Australia lmather@med.usyd.edu.au., Tucker GT; Clinical Pharmaology, The University of Sheffield, Sheffield, South Yorkshire, UK.
Publikováno v:
Regional anesthesia and pain medicine [Reg Anesth Pain Med] 2024 Feb 05; Vol. 49 (2), pp. 151. Date of Electronic Publication: 2024 Feb 05.
Autor:
Cremers S; Departments of Pathology & Cell Biology and Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, USA., Tucker GT; School of Medicine and Population Health, University of Sheffield, Sheffield, UK., Aronson JK; Centre for Evidence Based Medicine, Nuffield Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Oxford, UK., Ritter JM; Department of Clinical Pharmacology, Clinical Research Facility, St Thomas' Hospital, London, UK., Cohen AF; Leiden University Medical Centre and Centre for Human Drug Research, Leiden, The Netherlands.
Publikováno v:
British journal of clinical pharmacology [Br J Clin Pharmacol] 2024 Jan; Vol. 90 (1), pp. 4-11.
Autor:
Wesolowski CA; College of Pharmacy and Nutrition, University of Saskatchewan, 104 Clinic Place, Saskatoon, SK, S7N 2Z4, Canada. carl.wesolowski@gmail.com.; Department of Medical Imaging, Royal University Hospital, College of Medicine, University of Saskatchewan, 103 Hospital Drive, Saskatoon, SK, S7N 0W8, Canada. carl.wesolowski@gmail.com., Alcorn J; College of Pharmacy and Nutrition, University of Saskatchewan, 104 Clinic Place, Saskatoon, SK, S7N 2Z4, Canada., Tucker GT; Department of Human Metabolism, Medical and Biological Sciences, University of Sheffield, Sheffield, UK.
Publikováno v:
Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2022 Apr; Vol. 49 (2), pp. 191-208. Date of Electronic Publication: 2021 Oct 24.