Zobrazeno 1 - 10
of 107
pro vyhledávání: '"GSTA4"'
Autor:
Masahiro Adachi, Kota Yanagizono, Yasuhito Okano, Hitoshi Koizumi, Isao Uemaetomari, Keiji Tabuchi
Publikováno v:
Redox Report, Vol 28, Iss 1 (2023)
ABSTRACTCisplatin-induced ototoxicity is caused by reactive oxygen species. It has been recognized that estradiol (E2) regulates redox balance. However, little is known about the protective mechanisms of E2 against cisplatin-induced ototoxicity. In t
Externí odkaz:
https://doaj.org/article/4740cff77f354bd398f1334805e3e443
Akademický článek
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Autor:
Colin T. Shearn, Kristofer S. Fritz, Alisabeth H. Shearn, Laura M. Saba, Kelly E. Mercer, Bridgette Engi, James J. Galligan, Piotr Zimniak, David J. Orlicky, Martin J. Ronis, Dennis R. Petersen
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 68-77 (2016)
Chronic alcohol consumption induces hepatic oxidative stress resulting in production of highly reactive electrophilic α/β-unsaturated aldehydes that have the potential to modify proteins. A primary mechanism of reactive aldehyde detoxification by h
Externí odkaz:
https://doaj.org/article/a0c8a20508814e5c97a8857b03dd80be
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Aaron S. Gomez, Yong Hwan Kim, Thomas C. Foster, Mi-Jung Kim, Christina Rothenberger, Upal Bose, Richard Salvi, Isabela Caicedo, Karessa White, Senthilvelan Manohar, Hyo-Jin Park, Dalian Ding, Masaru Tanokura, Edith M. Sampson, Maria S. Ticsa, Paul J. Linser, Ashok V. Kumar, Shinichi Someya, Takuya Miyakawa, Chul Han, Kevin Boyd
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Cisplatin is one of the most widely used chemotherapeutic drugs for the treatment of cancer. Unfortunately, one of its major side effects is permanent hearing loss. Here, we show that glutathione transferase α4 (GSTA4), a member of the Phase II deto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef455fed7880214a94ab611dd2d6b78d
http://link.springer.com/article/10.1038/s41467-019-12073-0
http://link.springer.com/article/10.1038/s41467-019-12073-0
Publikováno v:
Journal of Dairy Science. 102:5530-5541
Enhancing the supply of rumen-protected Met (RPM) during the peripartum period alleviates inflammation and oxidative stress status in dairy cows. We tested the hypothesis that RPM could increase abundance of genes and proteins related to glutathione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e86f697fa39e8c45c9295760cf9f637
https://doi.org/10.3168/jds.2018-15687
https://doi.org/10.3168/jds.2018-15687
Publikováno v:
Brain Sciences, Vol 7, Iss 7, p 73 (2017)
Idiopathic Parkinson’s disease (PD) is a complex disease caused by multiple, mainly unknown, genetic and environmental factors. The Ventral root avulsion 1 (Vra1) locus on rat chromosome 8 includes the Glutathione S-transferase alpha 4 (Gsta4) gene
Externí odkaz:
https://doaj.org/article/c21570b959e845f0b712678cbfa5b771
Autor:
Rui Chen, Yuxin Zheng, Lianhua Cui, Qixiao Jiang, Daochuan Li, Menghui Jiang, Rong Zhang, Jingbo Pi, Jing Luo, Wen Chen, Mengyu Gao, Yuanyuan Ma
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Short-and long-term exposure to particulate matter (PM) has been associated with cardiovascular disease (CVD). It is well recognized that oxidative stress is a potential major mechanism in PM-induced vascular injuries, in which the nuclear factor E2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b5210b4bd699ea7bac5fb078c70b8d
https://doi.org/10.3389/fphar.2021.618023
https://doi.org/10.3389/fphar.2021.618023
Autor:
Se-Young Choung, Seo Yeon Jeong, Tong Ho Kang, Thu Nguyen Minh Pham, Kwang Won Jeong, Seung Hyun Kim, Yu Hwa Park, Do Hoon Kim, Kye Wan Lee, In Seok Moon, Jung Suk Lee
Publikováno v:
Nutrients
Volume 12
Issue 4
Nutrients, Vol 12, Iss 947, p 947 (2020)
Volume 12
Issue 4
Nutrients, Vol 12, Iss 947, p 947 (2020)
Despite the excellent antimicrobial activity of aminoglycoside antibiotics, permanent inner ear damage associated with the use of these drugs has resulted in the need to develop strategies to address the ototoxic risk given their widespread use. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af0b332177e167bf15f65cf96aa28fc
http://europepmc.org/articles/PMC7230542
http://europepmc.org/articles/PMC7230542
Autor:
David J. Orlicky, Kyle Meredith, Dennis R. Petersen, Kelly E. Mercer, Casey F. Pulliam, Martin J. J. Ronis, Colin T. Shearn, Laura Saba, Kim Brint Pedersen
Publikováno v:
Alcoholism: Clinical and Experimental Research. 42:1192-1205
BACKGROUND: Glutathione-S-transferase A4-4 (GSTA4) is a key enzyme for removal of toxic lipid peroxidation products such as 4-hydroxynonenal (4-HNE). In the current study, we examined the potential role of GSTA4 on protein carbonylation and progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77801c831ef2c26594593286cb93be6
https://doi.org/10.1111/acer.13766
https://doi.org/10.1111/acer.13766