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Autor:
Hegedűs, Csaba, Kovács, Katalin, Polgár, Zsuzsanna, Regdon, Zsolt, Szabó, Éva, Robaszkiewicz, Agnieszka, Forman, Henry Jay, Martner, Anna, Virág, László
Publikováno v:
Redox Biology, Vol 16, Iss, Pp 59-74 (2018)
Redox Biology
Redox Biology
Redox regulation has been proposed to control various aspects of carcinogenesis, cancer cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As cancer has many faces, the role of redox control in different cancers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::153be7bc8a9501b142b779dbaf4a96d6
http://www.sciencedirect.com/science/article/pii/S2213231717309424
http://www.sciencedirect.com/science/article/pii/S2213231717309424
Autor:
Claudia Moriconi, Valerio Licursi, Giuseppe Lupo, Emanuela D'Acunto, Emanuele Cacci, Elena Miranda, Nicoletta Carucci, Noemi Antonella Guadagno, Rodolfo Negri, Antonella De Jaco, Paola S. Nisi
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, Vol 103, Iss, Pp 32-44 (2017)
Neurobiology of Disease, Vol 103, Iss, Pp 32-44 (2017)
The serpinopathies are human pathologies caused by mutations that promote polymerisation and intracellular deposition of proteins of the serpin superfamily, leading to a poorly understood cell toxicity. The dementia FENIB is caused by polymerisation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80be70f0ed1b0fc6e7f713e96db2e01
http://europepmc.org/articles/PMC5439028
http://europepmc.org/articles/PMC5439028
Autor:
Wang, Qinqin1, Lu, Xuke1, Chen, Xiugui1, Malik, Waqar Afzal1, Wang, Delong1, Zhao, Lanjie1, Wang, Junjuan1, Wang, Shuai1, Guo, Lixue1, Cui, Ruifeng1, Han, Mingge1, Rui, Cun1, Zhang, Yuexin1, Fan, Yapeng1, Chen, Chao1, Ye, Wuwei1 yew158@163.com
Publikováno v:
Scientific Reports. 4/21/2021, Vol. 11 Issue 1, p1-15. 15p.
Autor:
Anna Zagórska, Alan R. Prescott, Maria Deak, Dario R. Alessi, David G. Campbell, Sourav Banerjee
Publikováno v:
Biochemical Journal
NUAK1 (NUAK family SnF1-like kinase-1) and NUAK2 protein kinases are activated by the LKB1 tumour suppressor and have been implicated in regulating multiple processes such as cell survival, senescence, adhesion and polarity. In the present paper we p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb065820cbf400858132f75eb94f908c
https://doi.org/10.1042/bj20140408
https://doi.org/10.1042/bj20140408
Autor:
Victoria H. Cowling, Michael Aregger
Publikováno v:
Biochemical Journal
Gene expression in eukaryotes is dependent on the mRNA methyl cap which mediates mRNA processing and translation initiation. Synthesis of the methyl cap initiates with the addition of 7-methylguanosine to the initiating nucleotide of RNA pol II (poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b73d26338571897e2cb923bc63e0095
http://europepmc.org/articles/PMC3778707
http://europepmc.org/articles/PMC3778707
Autor:
Julia Janzen, Elke Mühlberger, Steven C. Ley, Nicholas A. Morrice, Steven Howell, Thorsten Gantke, Sabrina Boussouf
Publikováno v:
Biochemical Journal
Activation of PKR (double-stranded-RNA-dependent protein kinase) by DNA plasmids decreases translation, and limits the amount of recombinant protein produced by transiently transfected HEK (human embryonic kidney)-293 cells. Co-expression with Ebola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c74292a5250f885ef51695960eb11d1
https://doi.org/10.1042/bj20121873
https://doi.org/10.1042/bj20121873
Autor:
Thomas Macartney, Youcef Mehellou, Frances-Rose Schumacher, Axel Knebel, Akihito Ohta, Dario R. Alessi, Nicola T. Wood, Clare Johnson, Thimo Kurz
Publikováno v:
Biochemical Journal
The WNK (with no lysine kinase)–SPAK (SPS1-related proline/alanine-rich kinase)/OSR1 (oxidative stress-responsive kinase 1) signalling pathway plays an important role in controlling mammalian blood pressure by modulating the activity of ion co-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070788786abe18caa6db90ba6b935486
https://doi.org/10.1042/bj20121903
https://doi.org/10.1042/bj20121903
Autor:
Zhenhua Shao, Fan Yang, Jihui Wu, Fudong Li, Dandan Qian, Minhao Wu, Yunyu Shi, Deshun Gong, Mian Wu
Publikováno v:
Biochemical Journal
Human RBM25 (RNA-binding motif protein 25) is a novel splicing factor that contains a PWI domain, a newly identified RNA/DNA-binding domain, and regulates Bcl-x pre-mRNA alternative splicing. The flanking basic region has been suggested to serve as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bc44ab74a1b2d42f5b0272b60bf061
https://doi.org/10.1042/bj20121382
https://doi.org/10.1042/bj20121382
Autor:
Philip M. Kubara, Aurélie Studeny, Sophie Kernéis-Golsteyn, Laurent Meijer, Roy M. Golsteyn, Brittany B. Lanser
Publikováno v:
Biochemical Journal
In the present paper, we report that mitosis is a key step in the cellular response to genotoxic agents in human cells. Cells with damaged DNA recruit γH2AX (phosphorylated histone H2AX), phosphorylate Chk1 (checkpoint kinase 1) and arrest in the G2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ce6f65b68f0615eee04df2d1069ff2
https://doi.org/10.1042/bj20120385
https://doi.org/10.1042/bj20120385